Protein

MIA_02399_1

Length
1,056 amino acids


Browser: contig03:689941-693112-

Protein function

EGGNOG:0PI3FFG06850.1Valyl-trna synthetase
SGD closest match:S000003326VAS1Valine--tRNA ligase, mitochondrial
CGD closest match:CAL0000181624VAS1Valine--tRNA ligase

Protein alignments

%idAln lengthE-value
MCA_01695_188.505%9830.0MCA_01695_1
A0A0J9X8G0_GEOCN77.127%10580.0Similar to Saccharomyces cerevisiae YGR094W VAS1 Mitochondrial and cytoplasmic valyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA05s01759g PE=3 SV=1
A0A167EK94_9ASCO76.041%9850.0Valine--tRNA ligase OS=Sugiyamaella lignohabitans GN=VAS1 PE=3 SV=1
A0A060TC23_BLAAD75.635%9850.0ARAD1D38962p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D38962g PE=3 SV=1
A0A1E3PJB7_9ASCO72.764%9840.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83077 PE=3 SV=1
Q6C109_YARLI71.122%9800.0YALI0F20218p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F20218g PE=3 SV=1
A0A1E4TM71_9ASCO68.896%9870.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1342 PE=3 SV=1
UniRef50_A0A1X7QYT769.176%9830.0Similar to Saccharomyces cerevisiae YGR094W VAS1 Mitochondrial and cytoplasmic valyl-tRNA synthetase n=3 Tax=Opisthokonta TaxID=33154 RepID=A0A1X7QYT7_9SACH
SYV_YEAST67.854%9830.0Valine--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VAS1 PE=1 SV=2
A0A1D8PHR0_CANAL63.800%10580.0Valine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VAS1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0020

Protein family membership

Domains and repeats

Detailed signature matches

    1. PR00986 (TRNASYNTHVAL)
    2. MF_02004 (Val_tRNA_...)
    1. PF00133 (tRNA-synt_1)
    1. SSF50677 (ValRS/Ile...)
    1. SSF47323 (Anticodon...)
    1. PF08264 (Anticodon_1)
    1. cd07962 (Anticodon_...)
    1. PS00178 (AA_TRNA_LI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52374 (Nucleotid...)
  2. cd00817 (ValRS_core)
  3. mobidb-lite (disord...)

Residue annotation

  1. active site cd00817
  2. HIGH motif cd00817
  3. KMSKS motif cd00817
  4. tRNA binding surfa...
  5. anticodon binding ...

Protein sequence

>MIA_02399_1
MSEKEQLPTDQQPSGEQPKVKTAKQLENERKKAEKLAKFEAKKAKQAQAKAQASADSKPKKAEKKPAAEPAPEFVDKTVP
GEKKILVSLDDPALKAYSPKNVESSWERWWASQGFFKPALTESGDIKPQGKFVIPAPPPNVTGALHIGHALTIAIQDSLI
RFNRMKGKTTLFVPGFDHAGISTQSVVEKMLWNREKKTRHDLGREKFVDLVWEWKEDYHARIKKQLHSLGASYDWDYEAF
TLDDTRSKAVVEAFVRLHDDGTIYRASRLVNWCVALNTTLSNLEVENKEITGRTLLKVPGYAEPVEFGVITSFAYPIENS
DEKLIVATTRPETMFGDSGIAVHPNDPRYKHLHGKFAIHPFLNRRIPIITDSEAVDMEFGTGAVKITPAHDPNDYATGKR
HNLEMINILNDDGTFNENAGPYAGMKRFDARKKVIEELKEKGLLIGSEDNPMTIPFCAKSNDVIEPLLKPQWWVAQKPQA
EASIKAVKEGKITIFPKTSENEFFSWLENIQDWCISRQLWWGHRCPVYFVKAVDESIEQDPADNQWWIAGRTLEEAQEKA
AKKFPDLKYTLEQDEDVLDTWFSSGLWPFSTLGWPENTEEMKKYYPMSLLETGWDILFFWVARMIMLGIKLTGQVPFTEV
FCHSLVRDAQGRKMSKSLGNVIDPLDVIYGTPLQTLHDKLKLGNLDPREIAKAEAGQKLSFPNGIPECGTDALRFALCAY
TTGGRDINLDILRVEGYRKFCNKIYQATKFALMRLGDDYKPPASLQPSGKESLVEKWILHKYTNAAQTIAKALDERDFLT
ATTAVYSYWLYELCDVYIENSKYLIVEGTPEEKKSAQDTLYIALEGALRLIHPFMPFITEELWQRIPKHADAPASISISS
YPEFDEKANNPDAEAAYNLILDVVKGARSILAQYNILKNATILVQASTADIQQTIAQQEASILSLVKAATKLEILGADAA
VPSGSVVSVISPEVSVFAIVKGHVDFDAEIEKAKNKISKAEKSKAQLEKQVNVKDYETKVRPEVREANQKRLENFAAEIS
GLQAVVDTFEKLKLDN

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006438 valyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004832 valine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm