Protein

MIA_02397_1

Length
392 amino acids

Browser: contig03:687165-688506-

Protein function

EGGNOG:0PGGYTPC1Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria (By similarity)
SGD closest match:S000003328TPC1Mitochondrial thiamine pyrophosphate carrier 1
CGD closest match:CAL0000175641TPC1Mitochondrial thiamine pyrophosphate carrier 1

Protein alignments

%idAln lengthE-value
MCA_01693_157.713%3766.71e-150MCA_01693_1
A0A0J9X9K9_GEOCN53.153%3332.05e-115Similar to Saccharomyces cerevisiae YBR192W RIM2 Mitochondrial pyrimidine nucleotide transporter OS=Geotrichum candidum GN=BN980_GECA05s02584g PE=3 SV=1
UniRef50_A0A0J9X9K953.153%3334.20e-112Similar to Saccharomyces cerevisiae YBR192W RIM2 Mitochondrial pyrimidine nucleotide transporter n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9K9_GEOCN
A0A1E3PLQ8_9ASCO44.290%3599.66e-98Mitochondrial thiamine pyrophosphate carrier 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82205 PE=3 SV=1
A0A167EG91_9ASCO43.902%3281.38e-86Tpc1p OS=Sugiyamaella lignohabitans GN=TPC1 PE=3 SV=1
A0A060TIJ7_BLAAD44.242%3302.29e-86ARAD1D39006p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D39006g PE=3 SV=1
TPC1_YARLI44.940%3364.21e-76Mitochondrial thiamine pyrophosphate carrier 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TPC1 PE=3 SV=1
A0A1E4TCW7_9ASCO39.688%3205.75e-66Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_141233 PE=3 SV=1
TPC1_CANAL37.209%3442.55e-59Mitochondrial thiamine pyrophosphate carrier 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TPC1 PE=3 SV=1
TPC1_YEAST29.607%3311.20e-42Mitochondrial thiamine pyrophosphate carrier 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPC1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0461

Protein family membership

Domains and repeats

  1. Domain
  2. Repeat
1 50 100 150 200 250 300 350 392

Detailed signature matches

  1. Family IPR002067
    Mitochondrial carrier protein
    1. PR00926 (MITOCARRIER)
  2. Domain IPR023395
    Mitochondrial carrier domain
    1. G3DSA:1.50.40.10
    2. SSF103506 (Mitochon...)
  3. Repeat IPR018108
    Mitochondrial substrate/solute carrier
    1. PS50920 (SOLCAR)
    2. PF00153 (Mito_carr)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. mobidb-lite (disord...)

Protein sequence

>MIA_02397_1
MSSPSPQKINLPAISSKDLAAGLAVAANQSTAAGSSGSQDPPRITPRAKQDAQGSGGPDKNHVLPIESTVSGAVAGLVSR
LVIAPLDVVKIRLQLEVDSKPPHGTGRRIFNKLKSIAYQEGFTALFKGNVPAEILYIAYGAAQFTTYKWTSNMLATALPN
TSDSAKSFASGATSACVATTLTYPFDLLRTRFAVQATPGNPRIYTSLYQAIRQIYHLEGASGFYRGIAPAVLTMVPYMGL
FFMSYEKLTHGLTYVLPTTQSLAESSNDTPSIPKFTVASLKALLASSHEAIAGLLAGIFAKTALFPFDVVRKRLQVQGPT
REKYLSGSIPKYPRNPFITAVMILRQEGILGLYKGLFVSIIKSAPASAVTMWTYEHTLDYMRKLKQDGYITY

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

None predicted.