Protein
MCA_01693_1
Length
405 amino acids
Gene name: TPC1
Description: mitochondrial thiamine pyrophosphate transporter; solute carrier family 25 member 19
Browser: contigA:5203480-5204849-
RNA-seq: read pairs 235, FPKM 7.2, percentile rank 20.8% (100% = highest expression)
Protein function
| Annotation: | TPC1 | mitochondrial thiamine pyrophosphate transporter; solute carrier family 25 member 19 | |
|---|---|---|---|
| KEGG: | K15108 | SLC25A19 | solute carrier family 25 (mitochondrial thiamine pyrophosphate transporter), member 19 |
| EGGNOG: | 0PGGY | TPC1 | Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria (By similarity) |
| SGD closest match: | S000003328 | TPC1 | Mitochondrial thiamine pyrophosphate carrier 1 |
| CGD closest match: | CAL0000175641 | TPC1 | Mitochondrial thiamine pyrophosphate carrier 1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02397_1 | 57.45% | 376 | 4e-147 | MIA_02397_1 |
| A0A0J9X9K9_GEOCN | 42.82% | 418 | 2e-105 | Similar to Saccharomyces cerevisiae YBR192W RIM2 Mitochondrial pyrimidine nucleotide transporter OS=Geotrichum candidum GN=BN980_GECA05s02584g PE=3 SV=1 |
| UniRef50_A0A0J9X9K9 | 42.82% | 418 | 4e-102 | Similar to Saccharomyces cerevisiae YBR192W RIM2 Mitochondrial pyrimidine nucleotide transporter n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9K9_GEOCN |
| A0A1E3PLQ8_9ASCO | 41.10% | 382 | 1e-84 | Mitochondrial thiamine pyrophosphate carrier 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82205 PE=3 SV=1 |
| A0A167EG91_9ASCO | 36.98% | 384 | 1e-73 | Tpc1p OS=Sugiyamaella lignohabitans GN=TPC1 PE=3 SV=1 |
| A0A060TIJ7_BLAAD | 36.44% | 376 | 2e-73 | ARAD1D39006p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D39006g PE=3 SV=1 |
| TPC1_YARLI | 40.26% | 380 | 7e-71 | Mitochondrial thiamine pyrophosphate carrier 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TPC1 PE=3 SV=1 |
| A0A1E4TCW7_9ASCO | 33.25% | 379 | 1e-60 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_141233 PE=3 SV=1 |
| TPC1_CANAL | 30.87% | 366 | 2e-44 | Mitochondrial thiamine pyrophosphate carrier 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TPC1 PE=3 SV=1 |
| TPC1_YEAST | 25.07% | 383 | 2e-36 | Mitochondrial thiamine pyrophosphate carrier 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPC1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0381
Protein family membership
- Mitochondrial carrier protein (IPR002067)
Domains and repeats
-
Domain
-
Repeat
1
50
100
150
200
250
300
350
405
Detailed signature matches
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_01693_1 MSKQHQNASTETSPSSDLSVNDKQKKSLENVKPIESTIAGGIAGLLSRLVIAPLDVVKIRLQLDTNKALKSGGNRRILDK LISIARDEGYTALFKGNVPAEIMYIGYGVLQFNTYRWTCKFIDDISATSSPKTITLPFTSLKIHLPKAKLNDSTKSFIAG SSSACVATTLTYPFDLLRTRFAIQATPGNPKVYKSLFRAFSQIYQNEGFTGFYRGLTPAIVAMIPYMGVFFASYQQIKNV LYYINPITKPFPEANGSANDSSSTLYSSKKSGSSSSSSIEEDGDIGSRLKRSVIQWLSTSNEGIAGLLAGIFAKTLLFPL DVIRKRLQVQGPTRNQYLSGTIPKYPRNPILTAVMIIQNEGILGLYKGLFISIIKSAPASAVTMWTYENSLNLMRYLNKK GYILY
GO term prediction
Biological Process
GO:0055085 transmembrane transport
Molecular Function
None predicted.
Cellular Component
None predicted.