Protein

MIA_02391_1

Length
615 amino acids

Browser: contig03:675532-677380-

Protein function

EGGNOG:0PGPYPGUG_05494Lariat debranching enzyme
SGD closest match:S000001632DBR1Lariat debranching enzyme
CGD closest match:CAL0000191567DBR1RNA lariat debranching enzyme

Protein alignments

%idAln lengthE-value
MCA_01795_150.760%3294.20e-109MCA_01795_1
A0A0J9X6B0_GEOCN47.386%3063.64e-93Similar to Saccharomyces cerevisiae YKL149C DBR1 RNA lariat debranching enzyme OS=Geotrichum candidum GN=BN980_GECA04s02529g PE=4 SV=1
UniRef50_M7NVJ440.351%3994.25e-93Uncharacterized protein n=4 Tax=Fungi TaxID=4751 RepID=M7NVJ4_PNEMU
A0A167E851_9ASCO35.729%4874.65e-89Dbr1p OS=Sugiyamaella lignohabitans GN=DBR1 PE=4 SV=1
A0A060TCU5_BLAAD42.627%3731.53e-86ARAD1D38720p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D38720g PE=4 SV=1
A0A1E3PMA9_9ASCO34.702%4871.97e-83Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46612 PE=4 SV=1
DBR1_YEAST39.130%3452.59e-80Lariat debranching enzyme OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBR1 PE=1 SV=1
Q6C9G7_YARLI41.642%3413.45e-78YALI0D11352p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D11352g PE=4 SV=1
A0A1E4T9U9_9ASCO36.496%4116.81e-75Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_33026 PE=4 SV=1
A0A1D8PPT8_CANAL38.904%3652.85e-74RNA lariat debranching enzyme OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DBR1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1881
Predicted cleavage: 35

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 615

Detailed signature matches

  1. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
  2. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
  3. Domain IPR007708
    Lariat debranching enzyme, C-terminal
    1. SM01124 (DBR1_2)
    2. PF05011 (DBR1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00844 (MPP_Dbr1_N)
  2. mobidb-lite (disord...)

Residue annotation

  1. active site cd00844
  2. metal binding site...

Protein sequence

>MIA_02391_1
MAILHVYFEGCCHGNLSAIYTAVQRLAKTQHPRDRVDLLLIGGDFQALRTASDLNCLAVPAKYKREAARGSFAAYFRGEL
AAPVLTVFVGGNHEASNYLQELPHGGWVAPNIYYLGRAGCVVYKNAVRIAGVSGIYDDRDYTRPYGERVPYSPRDLRSVY
HVRNYDVARLGLLASAQAWPRVSSVSAEALVGGGEPQPIDVFMSHDWPAGIEQHGDVRGLLRKKPFFAKDIAQGELGSPA
GMRLLRTLRPKTWVAAHLHVGFEATVEHGGAEAVGSKSVVNEDEIELDLDSDAEDGATDKAPDQPPEKTHFVALDKCLPR
RHFLQHIPIEVPGPASGARSPRTPSPGARKKKQKLASGAPVEAADARAAQFALDPRDRSLLSYDAAWLAVTRAMAPHVPV
PATEGFAPTPLARDAATGDLDTTPVTARVEGSPEGLSPLEQAAAWVDANVAAPGYLVIPTYEYFFGRPGGGPQSPRGSQS
PRGSREARHAWFRPELGDAGSAAVRGADRTAIVDNPQTARFCALVGIASWIAQLEQVPREPRESAGTRGGPRGAKTGQRG
ARDQRGGGWRGGQSGEQHYNLGGGGAPTSDARAESGHSSAGTPRYVSDSEEEGGV

GO term prediction

Biological Process

GO:0006397 mRNA processing

Molecular Function

GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds

Cellular Component

None predicted.