Protein

MIA_02389_1

Length
198 amino acids

Browser: contig03:671507-672316-

Protein function

EGGNOG:0PNFCRPC25DNA-directed RNA polymerase III
SGD closest match:S000001627RPC25DNA-directed RNA polymerase III subunit RPC8
CGD closest match:CAL0000199486orf19.443DNA-directed RNA polymerase III subunit

Protein alignments

%idAln lengthE-value
MCA_01797_178.000%2003.81e-119MCA_01797_1
A0A0J9XGA0_GEOCN70.202%1983.18e-104Similar to Saccharomyces cerevisiae YKL144C RPC25 RNA polymerase III subunit C25 OS=Geotrichum candidum GN=BN980_GECA15s01088g PE=4 SV=1
A0A060TCC8_BLAAD63.861%2021.58e-96ARAD1D35266p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35266g PE=4 SV=1
A0A1E3PMM4_9ASCO59.701%2012.15e-89Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45986 PE=4 SV=1
A0A1E4TEG9_9ASCO56.061%1982.15e-85Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_101697 PE=4 SV=1
Q6C9G5_YARLI56.436%2025.75e-81YALI0D11396p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D11396g PE=4 SV=1
UniRef50_B9W7U351.741%2012.06e-70DNA-directed RNA polymerase III 25 kDa subunit, putative n=12 Tax=Saccharomycetales TaxID=4892 RepID=B9W7U3_CANDC
Q5A298_CANAL51.741%2011.63e-73DNA-directed RNA polymerase III subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.443 PE=4 SV=1
RPC8_YEAST44.811%2128.34e-68DNA-directed RNA polymerase III subunit RPC8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPC25 PE=1 SV=1
A0A167E815_9ASCO72.656%1287.87e-64DNA-directed RNA polymerase III subunit RPC25 OS=Sugiyamaella lignohabitans GN=RPC25 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0957

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 20 40 60 80 100 120 140 160 180 198

Detailed signature matches

  1. Family IPR004519
    DNA-directed RNA polymerase, subunit E/RPC8
    1. TIGR00448
  2. Domain IPR005576
    RNA polymerase Rpb7, N-terminal
    1. PF03876 (SHS2_Rpb7-N)
    2. G3DSA:3.30.14...
    3. SSF88798 (N-termina...)
  3. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  4. Domain IPR013238
    RNA polymerase III, subunit Rpc25
    1. PF08292 (RNA_pol_Rbc25)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.50...
  2. cd04330 (RNAP_III_R...)

Residue annotation

  1. Rpc17 interaction ...

Protein sequence

>MIA_02389_1
MFVLTKISDLIRLDPQNFNTPLAEGLEDEVNKKFANKVIHNVGLCICLYDIEDFNDGMTKNGDGGVFIKCTFRLIVFRPF
VGEILVGWVSSCTEEGINIKMEFFDDIHIPKDLLFETCQFVPREQAWVWKNGEYDYFIDTNEKIRFRVEQEIFTQQQPRK
PSSLQMSDDPANQEIVHPPYSIIGSCQADGMGLVSWWD

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity

Cellular Component

None predicted.