MIA_02352_1

Protein

Length

1,635 amino acids

Protein function

EGGNOG:	0PHC3	FG07940.1	UDP-glucose glycoprotein glucosyltransferase
SGD closest match:	S000005863	KRE5	Killer toxin-resistance protein 5
CGD closest match:	CAL0000179466	KRE5	Kre5p

Protein alignments

	%id	Aln length	E-value
MCA_01810_1	51.41%	1626	0.0	MCA_01810_1
A0A0J9XG24_GEOCN	43.55%	1582	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA12s03376g PE=4 SV=1
UniRef50_A0A0J9XG24	43.55%	1582	0.0	Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XG24_GEOCN
A0A060TAK0_BLAAD	39.06%	1567	0.0	ARAD1D20196p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D20196g PE=4 SV=1
A0A1E3PFF7_9ASCO	37.20%	1567	0.0	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28763 PE=4 SV=1
A0A167DST0_9ASCO	62.53%	483	0.0	Kre5p OS=Sugiyamaella lignohabitans GN=KRE5 PE=4 SV=1
Q6CC41_YARLI	53.94%	597	0.0	YALI0C12661p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C12661g PE=4 SV=1
A0A1E4THD5_9ASCO	52.79%	591	0.0	Glycosyltransferase family 24 protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17832 PE=4 SV=1
A0A1D8PJN6_CANAL	41.94%	577	1e-136	Kre5p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KRE5 PE=4 SV=1
KRE5_YEAST	35.45%	220	8e-25	Killer toxin-resistance protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KRE5 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5542

Protein family membership

UDP-glucose:Glycoprotein Glucosyltransferase (IPR009448)

Domains and repeats

Domain
1,301 - 1,579
Nucleotide-diphospho-sugar transferases (IPR029044)

1 200 400 600 800 1000 1200 1400 1635

Detailed signature matches

IPR009448

UDP-glucose:Glycoprotein Glucosyltransferase
1. PF06427 (UDP-g_GGTase)
  
  32 - 1,243
  
  Pfam
  PF06427 (UDP-g_GGTase)
IPR029044

Nucleotide-diphospho-sugar transferases
1. G3DSA:3.90.55...
  
  1,301 - 1,579
  
  GENE3D
  G3DSA:3.90.550.10 (G3DSA:3.90.550.10)
2. SSF53448 (Nucleotid...)
  
  1,301 - 1,569
  
  SUPERFAMILY
  SSF53448 (Nucleotide-diphospho-sugar transferases)

no IPR

Unintegrated signatures

Coil

1,632 - 1,635

COILS
Coil (Coil)

420 - 446

COILS
Coil (Coil)
NON_CYTOPLASM... (N...)

23 - 1,635

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 22

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

19 - 22

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

8 - 18

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 7

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
SignalP-noTM

1 - 22

SignalP euk
SignalP-noTM (SignalP-noTM)
cd06432 (GT8_HUGT1_...)

1,301 - 1,548

CDD
cd06432 (GT8_HUGT1_C_like)
mobidb-lite (disord...)

1,238 - 1,258

MobiDB Lite
mobidb-lite (disorder_prediction)

417 - 450

MobiDB Lite
mobidb-lite (disorder_prediction)

1,586 - 1,635

MobiDB Lite
mobidb-lite (disorder_prediction)

264 - 283

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative ligand bi...

1,306V

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,307A

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,308S

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,311L

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,312Y

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,385I

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,401F

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,403D

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,404A

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,405D

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,430M

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,459I

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,460S

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,461A

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,497D

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,498Q

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,521E

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,522T

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,536D

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,538C

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,539N

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)

1,544K

putative ligand binding site
1,306V, 1,307A, 1,308S, 1,311L, 1,312Y, 1,385I, 1,401F, 1,403D, 1,404A, 1,405D, 1,430M, 1,459I, 1,460S, 1,461A, 1,497D, 1,498Q, 1,521E, 1,522T, 1,536D, 1,538C, 1,539N, 1,544K
CDD
cd06432 (GT8_HUGT1_C_like)
metal binding site...

1,403D

metal binding site
1,403D, 1,405D, 1,536D
CDD
cd06432 (GT8_HUGT1_C_like)

1,405D

metal binding site
1,403D, 1,405D, 1,536D
CDD
cd06432 (GT8_HUGT1_C_like)

1,536D

metal binding site
1,403D, 1,405D, 1,536D
CDD
cd06432 (GT8_HUGT1_C_like)

Protein sequence

>MIA_02352_1
MRGVFKPLLAAASAAWSVCASAADTSGLDLPKDINIDLKAEWDAVPFQLELVEAIASENSTIYHPLLLELSTNEQIEDTA
NPSDKLLYDTAIKFALDNGYISESAVPFIDLALGLHKHSAKIQAFYQYHDSVASSPSSEKCPVWISYNKKTSCDSDTVFA
LETKSNGISDNSLILPHDRVFGSRRDAPVAILYADITHKSFPVFHKHLYHSAENGKIRYILRYRKSVFDENDPQTSAPEK
QPLAGYGVELYVKRTDYLVIDDRDVKTENNENEDTTSNDHESKKIELKAADEGATIKKQNIPLIGVKAVGFIMNNENKFD
SLVNVSLDFPRYSHSISELPVDRDLKLELAKTRITPGANIIYINGAPVTQPNDDIFTITNAIQRERGFFSLFNELGIKSE
DAIKLITFADSPEQDILKSNDNFEKKNDAEKEEDDEEEEEDGDEEEKEYSKLKDSEYTRFDYRSSSLLWINDIVKDSQYR
RWSPSISQFRNTGQSHFLPIRHNAHTLIYAFDPSNEHHMRSLYDIMLIWQRNVPIQVALLPLPHDRLGEQITYEMYAIYE
NGKNRRGLTQYLSKLLSGVNHITAANSFYNTKKYESYRSIFDDKKIATALEEAKATARRLDIQVFDTHLPTIIVNGVFIT
PDPNWFYEMSQIVKSDSFIIKGLIEEGEIDDDDSDIVLKDILLQESFTRRNRIISSDASNIVYNSVDELYDTLWPNHQQN
SLSDNVASFVRERIAENTEDPDFVSTYWIFGKSHTKSFLNQVIQGLTFLSQSKDTFRLNVVPIIDPQASRSKQQTANIVN
TILYLLTSQKADLAYSKEAIENIYTALYGTYSEKRESPSLEEIKNKITPEDSFSTTQTHYDLTYHLISQLKTPEYKNIVN
SDLTIVSAGRVITLPDGVFLEHEDLGLLQEYEFKTRIKGLINISKILNLFDSIKASSKETGNYRHVSFAFVDKLVSLVSK
VKFNYVAKSSIYNVQYTRLDVEHWNLPKTSFEVGNKETALIHLTAVIDPLSEKGQVYISYLQSLSQIPNISIKVILNPKA
KIDSIPLKRFYRASLPIAPKFDSDGAIIKTSGDVVLSNMPQSTLLYIDLDVPPAWIVMPKKSIYDLDNIILDKVEPEGDG
NTALKGTYELKHVLIEGHASDVTRMEAPRGVALNLSPLDGPFFTDTIIMENLGYLQLKATPGLWQISLKEGPSAEIFEIE
STALTDGSELANPDQIWVTEFTGITIIPRLRRKRGMEGKDVLEQDTETTSDEQETGDSMKKAFEDAGKKLARSFSGLFKK
DTATQHKAQTALSAPKKNAEINIFSVASGHLYERFLSIMTYSVTAHTNHTVKFWIIENFLSPKFKDFLPYLAKERGFEYE
LVTYKWPHWLRHQTEKQRTIWGYKILFLDVLFPQSLDKIIFVDADQIVRTDMHDLVELDLHGAPYGFTPMCDSREEIEGF
RFWKQGYWKRYLGELKYHISALYVVDLVRFRELAAGDMLRQHYQMLSADPGSLSNLDQDLPNHLQRQLPIFSLPQDWLWC
ETWCSDESLLTAKTIDLCNNPMTKEPKLDRARRQVPEWTKYDDQVAALDKKVTKYLQEAEAIQDVPDLIPDLGDSDDESD
DDEEILKGAQKAKEEDHEIDYEAQLGEEENPHDEL

GO term prediction

Biological Process

GO:0006486 protein glycosylation

Molecular Function

GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features