MIA_02331_1

Protein

Length

1,163 amino acids

Protein function

EGGNOG:	0PGUP	SMC6	DNA repair protein
SGD closest match:	S000004375	SMC6	Structural maintenance of chromosomes protein 6
CGD closest match:	CAL0000185544	SMC6	DNA repair protein

Protein alignments

	%id	Aln length	E-value
MCA_03976_1	38.274%	1066	0.0	MCA_03976_1
A0A0J9XHA9_GEOCN	35.688%	1076	3.37e-174	Similar to Saccharomyces cerevisiae YLR383W SMC6 Protein involved in structural maintenance of chromosomes OS=Geotrichum candidum GN=BN980_GECA17s02419g PE=4 SV=1
UniRef50_A0A0J9XHA9	35.688%	1076	6.90e-171	Similar to Saccharomyces cerevisiae YLR383W SMC6 Protein involved in structural maintenance of chromosomes n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHA9_GEOCN
SMC6_YEAST	28.742%	1089	9.93e-95	Structural maintenance of chromosomes protein 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SMC6 PE=1 SV=1
Q5AGX1_CANAL	27.890%	1090	1.33e-92	DNA repair protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SMC6 PE=4 SV=1
A0A060T0P4_BLAAD	25.912%	1096	1.30e-88	ARAD1C09900p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09900g PE=4 SV=1
A0A161HGQ0_9ASCO	28.066%	791	9.13e-72	DNA repair protein SMC6 OS=Sugiyamaella lignohabitans GN=SMC6 PE=4 SV=1
A0A1E3PEY4_9ASCO	30.144%	627	6.57e-70	p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52937 PE=4 SV=1
Q6C360_YARLI	22.581%	1085	3.32e-36	YALI0F02365p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02365g PE=4 SV=1
A0A1E4TCA6_9ASCO	31.405%	121	1.12e-08	Structural maintenance of chromosomes protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_139250 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0034

Protein family membership

None predicted.

Domains and repeats

Domain
130 - 410
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
973 - 1,143
P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 200 400 600 800 1000 1163

Detailed signature matches

IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  130 - 410
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  130 - 178
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  973 - 1,143
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)

no IPR

Unintegrated signatures

Coil

363 - 407

COILS
Coil (Coil)

514 - 534

COILS
Coil (Coil)

830 - 871

COILS
Coil (Coil)

317 - 347

COILS
Coil (Coil)

904 - 934

COILS
Coil (Coil)

751 - 792

COILS
Coil (Coil)

451 - 478

COILS
Coil (Coil)

491 - 511

COILS
Coil (Coil)
G3DSA:1.20.12...

745 - 877

GENE3D
G3DSA:1.20.120.330 (G3DSA:1.20.120.330)

301 - 478

GENE3D
G3DSA:1.20.120.330 (G3DSA:1.20.120.330)
G3DSA:3.40.50...

129 - 300

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

896 - 1,157

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
PF13476 (AAA_23)

132 - 381

Pfam
PF13476 (AAA_23)
cd03276 (ABC_SMC6_euk)

1,059 - 1,163

CDD
cd03276 (ABC_SMC6_euk)

130 - 284

CDD
cd03276 (ABC_SMC6_euk)
mobidb-lite (disord...)

1 - 55

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Walker A/P-loop cd...

157G

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)

158H

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)

159N

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)

160G

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)

161S

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)

162G

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)

163K

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)

164S

Walker A/P-loop
157G, 158H, 159N, 160G, 161S, 162G, 163K, 164S
CDD
cd03276 (ABC_SMC6_euk)
ATP binding site c...

160G

ATP binding site
160G, 161S, 163K, 164S, 165A, 271Q
CDD
cd03276 (ABC_SMC6_euk)

161S

ATP binding site
160G, 161S, 163K, 164S, 165A, 271Q
CDD
cd03276 (ABC_SMC6_euk)

163K

ATP binding site
160G, 161S, 163K, 164S, 165A, 271Q
CDD
cd03276 (ABC_SMC6_euk)

164S

ATP binding site
160G, 161S, 163K, 164S, 165A, 271Q
CDD
cd03276 (ABC_SMC6_euk)

165A

ATP binding site
160G, 161S, 163K, 164S, 165A, 271Q
CDD
cd03276 (ABC_SMC6_euk)

271Q

ATP binding site
160G, 161S, 163K, 164S, 165A, 271Q
CDD
cd03276 (ABC_SMC6_euk)
Q-loop/lid cd03276

268I

Q-loop/lid
268I, 269L, 270S, 271Q
CDD
cd03276 (ABC_SMC6_euk)

269L

Q-loop/lid
268I, 269L, 270S, 271Q
CDD
cd03276 (ABC_SMC6_euk)

270S

Q-loop/lid
268I, 269L, 270S, 271Q
CDD
cd03276 (ABC_SMC6_euk)

271Q

Q-loop/lid
268I, 269L, 270S, 271Q
CDD
cd03276 (ABC_SMC6_euk)
ABC transporter si...

1,076L

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,077S

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,078G

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,079G

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,080E

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,081K

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,082S

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,083F

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,084S

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)

1,085Q

ABC transporter signature motif
1,076L, 1,077S, 1,078G, 1,079G, 1,080E, 1,081K, 1,082S, 1,083F, 1,084S, 1,085Q
CDD
cd03276 (ABC_SMC6_euk)
Walker B cd03276

1,100I

Walker B
1,100I, 1,101R, 1,102G, 1,103L, 1,104D, 1,105E
CDD
cd03276 (ABC_SMC6_euk)

1,101R

Walker B
1,100I, 1,101R, 1,102G, 1,103L, 1,104D, 1,105E
CDD
cd03276 (ABC_SMC6_euk)

1,102G

Walker B
1,100I, 1,101R, 1,102G, 1,103L, 1,104D, 1,105E
CDD
cd03276 (ABC_SMC6_euk)

1,103L

Walker B
1,100I, 1,101R, 1,102G, 1,103L, 1,104D, 1,105E
CDD
cd03276 (ABC_SMC6_euk)

1,104D

Walker B
1,100I, 1,101R, 1,102G, 1,103L, 1,104D, 1,105E
CDD
cd03276 (ABC_SMC6_euk)

1,105E

Walker B
1,100I, 1,101R, 1,102G, 1,103L, 1,104D, 1,105E
CDD
cd03276 (ABC_SMC6_euk)
ATP binding site c...

1,104D

ATP binding site
1,104D, 1,105E, 1,141P
CDD
cd03276 (ABC_SMC6_euk)

1,105E

ATP binding site
1,104D, 1,105E, 1,141P
CDD
cd03276 (ABC_SMC6_euk)

1,141P

ATP binding site
1,104D, 1,105E, 1,141P
CDD
cd03276 (ABC_SMC6_euk)
D-loop cd03276

1,108V

D-loop
1,108V, 1,109F, 1,110M, 1,111D
CDD
cd03276 (ABC_SMC6_euk)

1,109F

D-loop
1,108V, 1,109F, 1,110M, 1,111D
CDD
cd03276 (ABC_SMC6_euk)

1,110M

D-loop
1,108V, 1,109F, 1,110M, 1,111D
CDD
cd03276 (ABC_SMC6_euk)

1,111D

D-loop
1,108V, 1,109F, 1,110M, 1,111D
CDD
cd03276 (ABC_SMC6_euk)
H-loop/switch regi...

1,137I

H-loop/switch region
1,137I, 1,138F, 1,139I, 1,140T, 1,141P, 1,142N, 1,143P
CDD
cd03276 (ABC_SMC6_euk)

1,138F

H-loop/switch region
1,137I, 1,138F, 1,139I, 1,140T, 1,141P, 1,142N, 1,143P
CDD
cd03276 (ABC_SMC6_euk)

1,139I

H-loop/switch region
1,137I, 1,138F, 1,139I, 1,140T, 1,141P, 1,142N, 1,143P
CDD
cd03276 (ABC_SMC6_euk)

1,140T

H-loop/switch region
1,137I, 1,138F, 1,139I, 1,140T, 1,141P, 1,142N, 1,143P
CDD
cd03276 (ABC_SMC6_euk)

1,141P

H-loop/switch region
1,137I, 1,138F, 1,139I, 1,140T, 1,141P, 1,142N, 1,143P
CDD
cd03276 (ABC_SMC6_euk)

1,142N

H-loop/switch region
1,137I, 1,138F, 1,139I, 1,140T, 1,141P, 1,142N, 1,143P
CDD
cd03276 (ABC_SMC6_euk)

1,143P

H-loop/switch region
1,137I, 1,138F, 1,139I, 1,140T, 1,141P, 1,142N, 1,143P
CDD
cd03276 (ABC_SMC6_euk)

Protein sequence

>MIA_02331_1
MNMNSSDIHYYQGNTSQEYYHPAGSKRSREDADFPSDDYSELPENENYTSQDSAAYIKENDQQVIEEDQLDDDIDIDDQE
QEIAYDSTRGLSSQKIQEAKAVWNLKDPESIYYDEDVEAEDDNEPKSGAITKVHLQNFMCHENLEIELGRKVNFIVGHNG
SGKSAILTALAICLGGKASSTQRAGSLKGLIRNGTNKATITITIDNSSKNPYNPNVYGNKIVICRSFDHKSSNYKIKNQF
GETKFTTRDELNRILDYFQIIIDNPLAILSQDAARSFLTSSNPHSLYMFFSKGINHETWKKANGLTSSTVKETSQSYSTL
KESMNKIKDKEERLRKEFKDLKEQKEIGHRLAQLVKKIRWKAVENKEKEMEKYREKIAQYEARHDELERECKHNEEVLKE
LDKIEDDKNLELSAAMMKGKEADEDFNRQLRELDKFEAELGISSDNVRTAKKSINDSLARLNTLNAKLKREIERIEGGGL
RREQEEMRIKKQKYLEKLKSNNEQIEELGNTDSLEKELLNIDNESRRVQKLVQENRDNIASIKSDIESTEAASSRFENVF
GKKIEILLMAIDKNISRFSHPPLGPIGRYITIKEKEWAPIVASYLKRSLRAFVFQNHNDRAIFLEIVRRLKIDSFPTIVS
KPDLFKFENQMPDRSKYTTLYDILEFSNEHIKRVIIDQHGIEKIILVPNRAEAESIMFNNPRNVSKCFSIQNKLNGFSIG
GGTRGGSSSTPIFGQPPPYLMRIAENDSSQLDSLKVTLNDLYAKSRDLTKELGALTNQKRQKEKEISQVDDKISLLMNSS
KKLKQQINIIDDKLSEEIDMSQRGAIEKMIENTTNDFETYEKQLEKAKEEYENIKADVNDHKELLNTYQKKVNEVRDIQK
SIKLEMMETRDKKMSFKMESSRTVHDMQKMKLEAQNQQKSLESEAEVLKELTDQASESSPERLVVSQSLEDLQHEYTKTG
TALKASQLHNKSRSLEVVAEELLSCSKEFKRAKAEYKGAKFVNSSIDKMQARRDAKYHEFLKQITGTIQSKFRSILKQRD
FVGELQINHEEETMIVHSSRKSQDSKSVKDKDIKGLSGGEKSFSQIALLLAVWSAMSCLIRGLDEFDVFMDEVTRSVSMR
LMIDAINEGDLSKGQTIFITPNPMTELSNKEHVKIFRLADPKR

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_02331_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component