Protein

MCA_03976_1

Length
1,065 amino acids

Gene name: SMC6A

Description: Structural maintenance of chromosomes protein 6

Browser: contigC:1676777-1680302-

RNA-seq: read pairs 978, FPKM 11.3, percentile rank 28.1% (100% = highest expression)

Protein function

Annotation:SMC6AStructural maintenance of chromosomes protein 6
EGGNOG:0PGUPSMC6DNA repair protein
SGD closest match:S000004375SMC6Structural maintenance of chromosomes protein 6
CGD closest match:CAL0000185544SMC6DNA repair protein

Protein alignments

%idAln lengthE-value
MIA_02331_138.43%10670.0MIA_02331_1
A0A0J9XHA9_GEOCN33.18%10913e-178Similar to Saccharomyces cerevisiae YLR383W SMC6 Protein involved in structural maintenance of chromosomes OS=Geotrichum candidum GN=BN980_GECA17s02419g PE=4 SV=1
UniRef50_A0A0J9XHA933.18%10917e-175Similar to Saccharomyces cerevisiae YLR383W SMC6 Protein involved in structural maintenance of chromosomes n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHA9_GEOCN
A0A1E3PEY4_9ASCO29.07%11251e-112p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52937 PE=4 SV=1
Q5AGX1_CANAL28.36%10932e-98DNA repair protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SMC6 PE=4 SV=1
A0A060T0P4_BLAAD27.03%11063e-89ARAD1C09900p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09900g PE=4 SV=1
SMC6_YEAST26.83%11071e-85Structural maintenance of chromosomes protein 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SMC6 PE=1 SV=1
A0A161HGQ0_9ASCO30.97%6202e-76DNA repair protein SMC6 OS=Sugiyamaella lignohabitans GN=SMC6 PE=4 SV=1
Q6C360_YARLI25.70%11096e-51YALI0F02365p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02365g PE=4 SV=1
A0A1E4TDV6_9ASCO31.13%1515e-13Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1669 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0726

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1065

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR003395
    RecF/RecN/SMC, N-terminal
    1. PF02463 (SMC_N)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.28...
  3. G3DSA:3.40.50...
  4. cd03276 (ABC_SMC6_euk)

Residue annotation

  1. Walker A/P-loop cd...
  2. ATP binding site c...
  3. Q-loop/lid cd03276
  4. ABC transporter si...
  5. Walker B cd03276
  6. ATP binding site c...
  7. D-loop cd03276
  8. H-loop/switch regi...

Protein sequence

>MCA_03976_1
MTGDLLTAMDQRYDTFFQPSVEARVSQKRKAPPPRTAGAIVKIQLQNFMCHENLIVELGPKINFIVGHNGSGKSAILTAL
SICLGGKASGTQRAASLKQFIREGTSRALISVTLNNTGEEAYNPEQYGDAIIIERVIERAGTSHYKAKSAAGKIIGHTKD
ALLDILDHFEIIVDNPLAILSQDMARSFLNGVDTNQLYKFLSNGIQHEVWKKLYTSTVTNVDEATKAIPVLKEQVAIRSA
RVGELQREHTLLENQKIEAQRLGRIAAQIQWKNVELKEFEIQDQETLLEELQSESNAIENQINIQHKAITESKLNIEAIV
KQRPELLLVKDTKAQELQRAKAEFMDVRDQLRQHDATLDELKLAIRTRDSKIKDLQIRLQKEKHQMEGGYEQDRVKWEKS
KTEKMKTIQDLELKIAEWKSERNNLEDSLSQLRNEIKDHENDFREARTEVEQYMEALENMDGSEAKFMNRFGPSIGRVLK
EIEEEKRFTAKPIGPIGAFITLKKSEWTSILTRVFDNTLESFVVQNSQDMNLLRHIMNRNHMDSPIIISAPDLYDIELPD
RQYTTIYDILEFSNDHLKRVMIDRHKINAIIIETNRQMGEKIMLSRPRNVISCFAMTGRNECTSITNTKGSSSTTPVYGR
LRPYYLMREESKTGQKDNITSLLEEAKAKYQLANKQYRKIKEQLTSNERGINFLKNKINEAQITIDRLKRDVDKLDDKLS
QEIDDSVITTLNDNIVSLQEEQNTDLNQLRDAETARVELKNNVDDYNSLMEAISQQLKSAESELHRNVRAENDLNSKFIH
LESKIKKLQHDLDSQHQRVDAQKQHIANLNAELNDLIRAAKEKSEERLRTLDTLQTLESKYMELRNSIEAAKEMSKHRDI
TQVIRELKEATEAYKIAKEQFSVAHRTVQKLQKMQKERKAHYDILLAATTSNIIQTFNQILDERDFEGKLEIDHVNQTMS
IGAAPRARGEGSSKNTKSLSGGEKSFSQIALLLAVWSAMSCRLRGLDEFDVFMDEVNRKFSMKLMIEAIYSLDQGQTIFI
TPNNMADIKVNKNDVTILRLADPKR

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.