Protein
MIA_02313_1
Length
1,065 amino acids
Browser: contig03:445395-448647+
Protein function
| EGGNOG: | 0PK7X | ATG13 | Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also invoved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity) |
|---|---|---|---|
| SGD closest match: | S000006389 | ATG13 | Autophagy-related protein 13 |
| CGD closest match: | CAL0000176796 | ATG13 | Autophagy-related protein 13 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_04218_1 | 50.292% | 342 | 3.93e-90 | MCA_04218_1 |
| A0A060T6L4_BLAAD | 49.200% | 250 | 5.81e-71 | Autophagy-related protein 13 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C21120g PE=3 SV=1 |
| UniRef50_A0A060T6L4 | 49.200% | 250 | 1.44e-67 | Autophagy-related protein 13 n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T6L4_BLAAD |
| A0A0J9XKQ2_GEOCN | 40.822% | 365 | 1.51e-64 | Autophagy-related protein 13 OS=Geotrichum candidum GN=BN980_GECA24s00494g PE=3 SV=1 |
| ATG13_YARLI | 46.964% | 247 | 3.24e-64 | Autophagy-related protein 13 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ATG13 PE=3 SV=1 |
| A0A1E3PFQ7_9ASCO | 35.674% | 356 | 2.08e-59 | Autophagy-related protein 13 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83787 PE=3 SV=1 |
| ATG13_CANAL | 43.388% | 242 | 1.12e-51 | Autophagy-related protein 13 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ATG13 PE=3 SV=2 |
| A0A1E4TL46_9ASCO | 38.889% | 252 | 7.70e-48 | Autophagy-related protein 13 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30622 PE=3 SV=1 |
| A0A167FAS6_9ASCO | 39.791% | 191 | 9.35e-36 | Autophagy-related protein 13 OS=Sugiyamaella lignohabitans GN=ATG13 PE=3 SV=1 |
| ATG13_YEAST | 31.818% | 264 | 4.78e-25 | Autophagy-related protein 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG13 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.5421
Predicted cleavage: 42
Protein family membership
- Autophagy-related protein 13 (IPR018731)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MIA_02313_1 MSIQRDSYNKTKLNQIVQQFFSKAAQIVIQSRILVTPLYVKGTATPKLNRWFNLELEETETFREDLRLWKSADPQEAVIP PLVVETYLDLRDLSANQTLILIDSKGKSWTVTKGTKRTEIVLERWIIENTEGLKSDQNQELPTIYKYVIILMRSLYTYTR LMPVWNLKNKLSAKPQNTLLNVGCRILNGSHGISSKGRIGLNRRIKDVDSIEVNCFSFDEIPTPLGTLKVTVSYRTECDF FIKNSSIQSLPSNISTSQTDVNSGLNINTNFHLESDSILNMEPSTSYASKNDSKPTIIKRSSVSSLTQGSLPSPSRSSIE GNSYMISRHNVYKNHTKNYSADFTDNVQNFSTQYNTSGDQYLARDRRLSSVSLRDGLISSGGTGSTTIQQNVSGTSPSAN VSSQSVSSPIATKPSVSFVQPFKTPSLSASPSSGDITFQSSSTPSSRPQSFSRTTSNSSLAALAALRNPNRTSSNASNTS VGSYIKNAANMHQTYLNENAISSSASSSRSGSVSRYSSSFGSRTGQWNRTGSISGNRPKPLFSGDPSSFGSSTSSVTEPG SGFLMTDDDDLGAFLKTIDAMAYARNNNSSVILQGSGSNNSSLLMSQPRYDANLPGASTNTENSSIGEINLAAGENSDDP LSRFRHLKESHTALSDSMHSSQISRSDVSPLGGSSGQNVAPGSAGSSSASPSQAVFTFAMSPPSIQKTSSSYTPSIPSRL SEQYTPDDSYKVRYNIHPRKHGSRSGSLAIDEEMYIHGDHGNSMSSSKDEQNVSSSARTGALDIPRTHVSRVQRRESLSF SNRHTSGYKDMQDALVLNNSNTHHQSLNTFGQELPGATSTDFRANTTANSPAFSSHRRYSTDVLGSEGHISSFNRPQSHT NSGGSSFANNGNRKISSFISTNSNSNNTSGNDDSSNSTNAGNLHHQLESLPGNFRQQVSLAGGESHIHSHHLGQHHHHIA PSSSSVRSRRFSYYLPDDGDDDDDDGDGDDREQKTSPNAHAAESLPPMDEDVFFFALNDDEENVKGSSSGGITGSGTGGV NTGSGAGSPSGGGRFNHSYDSLAWE
GO term prediction
Biological Process
GO:0006914 autophagy
Molecular Function
None predicted.
Cellular Component
GO:1990316 ATG1/ULK1 kinase complex