Protein
MCA_04218_1
Length
1,072 amino acids
Gene name: ATG13
Description: Autophagy-related protein 13
Browser: contigC:2381840-2385152-
RNA-seq: read pairs 816, FPKM 9.4, percentile rank 25.1% (100% = highest expression)
Protein function
| Annotation: | ATG13 | Autophagy-related protein 13 | |
|---|---|---|---|
| KEGG: | K08331 | ATG13 | autophagy-related protein 13 |
| EGGNOG: | 0PK7X | ATG13 | Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also invoved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity) |
| SGD closest match: | S000006389 | ATG13 | Autophagy-related protein 13 |
| CGD closest match: | CAL0000176796 | ATG13 | Autophagy-related protein 13 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02313_1 | 48.66% | 857 | 3e-173 | MIA_02313_1 |
| A0A060T6L4_BLAAD | 47.60% | 250 | 1e-69 | Autophagy-related protein 13 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C21120g PE=3 SV=1 |
| UniRef50_A0A060T6L4 | 47.60% | 250 | 3e-66 | Autophagy-related protein 13 n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T6L4_BLAAD |
| ATG13_YARLI | 42.91% | 247 | 1e-60 | Autophagy-related protein 13 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ATG13 PE=3 SV=1 |
| A0A0J9XKQ2_GEOCN | 40.61% | 261 | 1e-57 | Autophagy-related protein 13 OS=Geotrichum candidum GN=BN980_GECA24s00494g PE=3 SV=1 |
| A0A1E3PFQ7_9ASCO | 33.66% | 303 | 9e-50 | Autophagy-related protein 13 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83787 PE=3 SV=1 |
| ATG13_CANAL | 40.32% | 253 | 7e-49 | Autophagy-related protein 13 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ATG13 PE=3 SV=2 |
| A0A167FAS6_9ASCO | 42.70% | 185 | 4e-38 | Autophagy-related protein 13 OS=Sugiyamaella lignohabitans GN=ATG13 PE=3 SV=1 |
| A0A1E4TL46_9ASCO | 34.54% | 249 | 4e-38 | Autophagy-related protein 13 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30622 PE=3 SV=1 |
| ATG13_YEAST | 32.26% | 279 | 4e-27 | Autophagy-related protein 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG13 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0558
Protein family membership
- Autophagy-related protein 13 (IPR018731)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MCA_04218_1 MSMKKSEKGSESNRVHQIIQQFFCKSAQVITQSRISSTSFTDNSNSKTSRWFNLELEETDAFKDELRLWKNVDPESEHGI PPLVVETFLNLRDLTPDQSLVLLGPEGKQWIVTKGTKRNEVVLERWIIEFITSDNQKSDQLELPTIYKHVIILMRSLYTY ARLMPSMNLKRRLSSSKLNIPPISIGCRVINGSNTISSKGRVGLNKPIKGKGIVETDCISFDEIATPLGNLQVSVTYRLD HEFIVEDNPASALSHNSQNLFGKYANKGYNPSFSSSPTNPVSTNSTTNPALIPSFGNSRRSSVSSNNQLSNASPSRSSID GNSYLIGRSNAYRSHNRHNSIDFSSDNDSSSNLPGSFNGPYIGDQAYRDRRLSSISVRDQHPFQHHGSSPSGNTPISPTA TKPSVSFTQPFKTPSLSASPYSNEIGFPANSSNSRPSSFSRTTSNSSLAALRIPNKSTPMASAGSLVGSSSVKNSSGSSH PFAGVLDPNNMSNPNAIVSSASSSRSGSVSRYSSSFGSRTGQWTRAGSISGTRPKRASFGDPSSLGSAIASSTSSSLGDN LSGMLSSDKDDLSSFIKHLDAISLGKVPNSSSSILLGSGSNTNLSSGGGNGSSLLLPQLGSNTIQQNPTTGSIGDSDDDK LSKFRHLKESHMALSDSMHSSHKLDNNSPTSGGSTASPSQGLFSFAMSPPPVVQKTVSSHTPTVPSRLSEEFTADETYKA KKYYSHPRKQGSRSSLPIDEEMFIPDDKSEQDVSESAKTHALDIPQTHVTRLQQRESLSISNRHTSGYKDMQDGLDLSNN AYHQSLNGVGHIIPGKELSSFRSNNPNDNDSNSNTMASNHITTLRGHRFSFSGNSSSSNKNSTKNMHVSSSPGSGNGAHD IQEDKGRYTRSNSNLMMTSSSASPRSGGIVNNPAAAASSSNVSSSLNDRRNSSNGLHHVRNHTIEGSSNVMMSMGNHHHH SHSRQTSTSLRSRRLSAYYLPDDEEDADDEDGQEELEDDDKDKDIMAPLDDDDVFFFALNDEEEDSAGVSVSTSNNDDNE SSSTNNTNNNNNGLFHHSNLNSSNRYDALRWE
GO term prediction
Biological Process
GO:0006914 autophagy
Molecular Function
None predicted.
Cellular Component
GO:1990316 ATG1/ULK1 kinase complex