Protein

MIA_02303_1

Length
369 amino acids

Browser: contig03:408571-409740-

Protein function

EGGNOG:0PHJ3CPR6Peptidyl-prolyl cis-trans isomerase
SGD closest match:S000004206CPR6Peptidyl-prolyl cis-trans isomerase CPR6
CGD closest match:CAL0000193303CPR6Peptidyl-prolyl cis-trans isomerase D

Protein alignments

%idAln lengthE-value
MCA_04236_169.482%3675.99e-166MCA_04236_1
A0A0J9XE02_GEOCN62.363%3643.66e-161Similar to Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (Cyclophilin) OS=Geotrichum candidum GN=BN980_GECA11s02353g PE=4 SV=1
UniRef50_Q6BXZ759.401%3675.04e-144Peptidyl-prolyl cis-trans isomerase D n=62 Tax=Eukaryota TaxID=2759 RepID=PPID_DEBHA
PPID_CANAL58.445%3731.20e-145Peptidyl-prolyl cis-trans isomerase D OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CPR6 PE=3 SV=2
A0A1E3PM41_9ASCO60.822%3654.11e-138Peptidyl-prolyl cis-trans isomerase D OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82306 PE=4 SV=1
PPID_YARLI54.670%3645.15e-133Peptidyl-prolyl cis-trans isomerase D OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CPR6 PE=3 SV=1
A0A060TAR1_BLAAD55.526%3719.24e-125ARAD1B02706p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02706g PE=4 SV=1
A0A1E4TKY2_9ASCO52.446%3682.32e-120Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_86310 PE=4 SV=1
A0A167EPM2_9ASCO49.211%3807.66e-117Peptidylprolyl isomerase CPR6 OS=Sugiyamaella lignohabitans GN=CPR6 PE=4 SV=1
PPID_YEAST49.866%3733.71e-112Peptidyl-prolyl cis-trans isomerase CPR6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CPR6 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0240

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Repeat
  3. Repeat
1 50 100 150 200 250 300 369

Detailed signature matches

  1. Domain IPR029000
    Cyclophilin-like domain
    1. SSF50891 (Cyclophil...)
    2. G3DSA:2.40.10...
  2. Domain IPR002130
    Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
    1. PF00160 (Pro_isomerase)
    2. PS50072 (CSA_PPIASE_2)
    3. PR00153 (CSAPPISMRASE)
  3. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
    2. SSF48452 (TPR-like)
  4. Domain IPR013026
    Tetratricopeptide repeat-containing domain
    1. PS50293 (TPR_REGION)
  5. Repeat IPR019734
    Tetratricopeptide repeat
    1. PS50005 (TPR)
    2. SM00028 (tpr_5)
  6. Repeat IPR013105
    Tetratricopeptide repeat 2
    1. PF07719 (TPR_2)
  7. SITE IPR020892
    Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    1. PS00170 (CSA_PPIASE_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd01926 (cyclophili...)

Residue annotation

  1. active site cd01926

Protein sequence

>MIA_02303_1
MTARPRVFFDITIGGELKGKVVFELFNDVVPKTAENFRALCTGEKGIGKLGKPLCYKGSTFHRVIKGFMIQGGDFTAGNG
TGGESIYGEKFEDENLDTSTLKHDRPFLLSMANAGPNTNGSQFFVTTVPTQHLDGKHVIFGQVLSGKSVIRAVEKTKTGP
NDRPEEDVVIANCGEYPADEPLPPKIDDGTGDKYEESIADDESIDINKPASVFAAVQDLKSIGTRLYKEGNLSKAFEKYT
KASRFLEEYFPEDLSDADLKTDQDLKVSLYLNIAIVALRLNKNLDALDAAKNAMEVGEIGNQEKAKALYRMGSAYLGLKN
HEESIAKYQEALKYAPNDSAILQGLNNAKTKLKERNQKERAVFSKFFSQ

GO term prediction

Biological Process

GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

Molecular Function

GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding

Cellular Component

None predicted.