Protein

MCA_04236_1

Length
381 amino acids

Gene name: CPR6A

Description: Peptidyl-prolyl cis-trans isomerase D

Browser: contigC:2442264-2443515+

RNA-seq: read pairs 4416, FPKM 142.8, percentile rank 84.3% (100% = highest expression)

Protein function

Annotation:CPR6APeptidyl-prolyl cis-trans isomerase D
KEGG:K05864PPID peptidyl-prolyl isomerase D [EC:5.2.1.8]
EGGNOG:0PHJ3CPR6Peptidyl-prolyl cis-trans isomerase
SGD closest match:S000004206CPR6Peptidyl-prolyl cis-trans isomerase CPR6
CGD closest match:CAL0000193303CPR6Peptidyl-prolyl cis-trans isomerase D

Protein alignments

%idAln lengthE-value
MIA_02303_169.52%3519e-149MIA_02303_1
A0A0J9XE02_GEOCN64.18%3496e-135Similar to Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (Cyclophilin) OS=Geotrichum candidum GN=BN980_GECA11s02353g PE=4 SV=1
PPID_YARLI61.45%3457e-121Peptidyl-prolyl cis-trans isomerase D OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CPR6 PE=3 SV=1
UniRef50_Q6BXZ759.20%3482e-114Peptidyl-prolyl cis-trans isomerase D n=62 Tax=Eukaryota TaxID=2759 RepID=PPID_DEBHA
A0A1E3PM41_9ASCO60.92%3486e-117Peptidyl-prolyl cis-trans isomerase D OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82306 PE=4 SV=1
PPID_CANAL57.39%3456e-112Peptidyl-prolyl cis-trans isomerase D OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CPR6 PE=3 SV=2
A0A060TAR1_BLAAD56.21%3543e-110ARAD1B02706p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02706g PE=4 SV=1
A0A1E4TKY2_9ASCO55.59%3403e-106Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_86310 PE=4 SV=1
A0A167EPM2_9ASCO51.00%3494e-97Peptidylprolyl isomerase CPR6 OS=Sugiyamaella lignohabitans GN=CPR6 PE=4 SV=1
PPID_YEAST53.43%3501e-94Peptidyl-prolyl cis-trans isomerase CPR6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CPR6 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1774

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Repeat
  3. Repeat
1 50 100 150 200 250 300 350 381

Detailed signature matches

  1. Domain IPR029000
    Cyclophilin-like domain
    1. SSF50891 (Cyclophil...)
    2. G3DSA:2.40.10...
  2. Domain IPR002130
    Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
    1. PF00160 (Pro_isomerase)
    2. PS50072 (CSA_PPIASE_2)
    3. PR00153 (CSAPPISMRASE)
  3. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
    2. SSF48452 (TPR-like)
  4. Domain IPR013026
    Tetratricopeptide repeat-containing domain
    1. PS50293 (TPR_REGION)
  5. Repeat IPR019734
    Tetratricopeptide repeat
    1. PS50005 (TPR)
    2. SM00028 (tpr_5)
  6. Repeat IPR013105
    Tetratricopeptide repeat 2
    1. PF07719 (TPR_2)
  7. SITE IPR020892
    Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    1. PS00170 (CSA_PPIASE_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd01926 (cyclophili...)

Residue annotation

  1. active site cd01926

Protein sequence

>MCA_04236_1
MSSQRPRVFFDIAIGGVPKGKIVFELFNDVVPKTAENFRALCTGEKGMGKLGKPLSYKGSTFHRVIKKFMIQGGDFTQGN
GTGGESIYGEKFEDENFNLKHDKPFLLSMANAGPDTNGSQFFITTVETPHLDQKHVVFGQVLAGKNVVREIENTPTGPND
KPDLDVVITDCGEYPLDADLPSKPDDGTGDIYEDFLADEPKVDTKDPASVFKVVEEIKSIGTKLFKEKNYEKAYEKYSKA
SRYLEDYFPDNLNDDDLKKDTDLKVSLYLNVSLLASKINKYKEAVSAAENALEVGELGPKEKAKAYYRMGNGYLGLKNPE
DAIKNYVEAAKYAPADAAISAGIKHAREVLEERKKKEKAAFSKFFSSTKKEEKSNNEEKKN

GO term prediction

Biological Process

GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

Molecular Function

GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding

Cellular Component

None predicted.