Protein
MIA_02301_1
Length
705 amino acids
Browser: contig03:392860-394978-
Protein function
| EGGNOG: | 0PHC0 | PGUG_00888 | resistance protein |
|---|---|---|---|
| SGD closest match: | S000001090 | YHK8 | Probable drug/proton antiporter YHK8 |
| CGD closest match: | CAL0000189339 | orf19.3395 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05037_1 | 40.319% | 439 | 5.02e-85 | MCA_05037_1 |
| A0A0J9XBN0_GEOCN | 38.326% | 454 | 5.72e-80 | Similar to Saccharomyces cerevisiae YHR048W YHK8 Presumed antiporter of the DHA1 family of multidrug resistance transporters OS=Geotrichum candidum GN=BN980_GECA08s01979g PE=4 SV=1 |
| UniRef50_A0A0F8CVP5 | 32.087% | 508 | 1.36e-61 | Putative drug/proton antiporter YHK8 n=35 Tax=leotiomyceta TaxID=716546 RepID=A0A0F8CVP5_CERFI |
| A0A167BZ56_9ASCO | 32.233% | 515 | 5.92e-54 | Yhk8p OS=Sugiyamaella lignohabitans GN=YHK8 PE=4 SV=1 |
| Q5A4P7_CANAL | 30.921% | 456 | 5.70e-54 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3395 PE=4 SV=1 |
| A0A1E4TE36_9ASCO | 31.868% | 455 | 6.51e-53 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_99540 PE=4 SV=1 |
| A0A060TG04_BLAAD | 30.631% | 444 | 4.78e-50 | ARAD1D27214p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27214g PE=4 SV=1 |
| YHK8_YEAST | 26.712% | 438 | 2.05e-49 | Probable drug/proton antiporter YHK8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHK8 PE=1 SV=1 |
| Q6CGJ0_YARLI | 30.470% | 489 | 2.34e-46 | YALI0A18920p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A18920g PE=4 SV=1 |
| A0A1E3PF73_9ASCO | 28.472% | 432 | 4.91e-46 | MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84082 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9234
Predicted cleavage: 32
Protein family membership
- Major facilitator superfamily (IPR011701)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
705
Detailed signature matches
-
-
PF07690 (MFS_1)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
Residue annotation
-
putative substrate...
Protein sequence
>MIA_02301_1 MPRHKIKHQTHNVYPRRVSRVVTDHTFRQRQKTYASPPAGGLAKLHQGIWQLDNSSTESLETVWSSDSEKSSLLFKERDQ YNNYRHTWIPGLTHSSTAVVYASSPTIPTMSYMVQNCGGTEMPPDPYLVEWTGDIFLDFENVKLTTSAGRKLVYTTVICL AVVVVTCLSSVYSMAMPAITREFLGQDGQPPAVVMLGLTLYLLGMAVGPLVFAPMSEVYGRRVMYAFSFFCALAFNFGCA FACSLGGLLACRFLTGLFASGFVGVAAGTIGDLYDTPQEMQVASMLFTSAPVIGPAIGPMFAGSLVSGKGNNDWRWCFHV MSMALTGIYLFVALVVPETCESILLERKAARVRQVTKNNGYYTTRNRIISQRRQHLAERVPLYMQWVVPMLDLTMLVCES VQKPVHMLLHEPMLALLCGYSGLLLAVMYMFFVSYPRVFSQTYGFNSHQVGLAFGGLLCGAVLAIPTVWVNGQWVRRQQQ ELKKKIERYGKEDGGDCDGVDAYYEPEMQLKQSMIGSLVVPVGMLVFSWCARPGVSWVVCVIGGGIVNWGSVLTSNGIYA YTLTAWGGSRVCKKSSKVSPPDIVAASEVAAAAVSPGRVSGLRATCKKVGSVSEAGEPCFGTVANSASAANSGQAASAAS AMACNGLVRSVMGSVAPLAGQQMYRGLGSAWAGTLVACFCVAYVPLPVLFYRYGRRLRAKSRYAV
GO term prediction
Biological Process
GO:0055085 transmembrane transport
Molecular Function
None predicted.
Cellular Component
GO:0016021 integral component of membrane