Protein

MIA_02269_1

Length
213 amino acids

Browser: contig03:320941-321711-

Protein function

EGGNOG:0PPNMGAR1Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ( psi ) residues may serve to stabilize the conformation of rRNAs
SGD closest match:S000001131GAR1H/ACA ribonucleoprotein complex subunit 1
CGD closest match:CAL0000187800GAR1H/ACA ribonucleoprotein complex subunit

Protein alignments

%idAln lengthE-value
MCA_06498_191.579%952.14e-59MCA_06498_1
Q6CAV4_YARLI81.443%971.63e-54H/ACA ribonucleoprotein complex subunit OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C24057g PE=3 SV=1
A0A161HN04_9ASCO84.946%932.91e-54H/ACA ribonucleoprotein complex subunit OS=Sugiyamaella lignohabitans GN=GAR1 PE=3 SV=1
A0A060TGS1_BLAAD83.871%932.79e-54H/ACA ribonucleoprotein complex subunit OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32956g PE=3 SV=1
UniRef50_H2AUT480.208%967.35e-50H/ACA ribonucleoprotein complex subunit n=7 Tax=Opisthokonta TaxID=33154 RepID=H2AUT4_KAZAF
GAR1_YEAST79.787%948.54e-53H/ACA ribonucleoprotein complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAR1 PE=1 SV=1
A0A1D8PF56_CANAL78.125%963.58e-51H/ACA ribonucleoprotein complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GAR1 PE=3 SV=1
A0A0J9X7X6_GEOCN79.570%933.41e-49H/ACA ribonucleoprotein complex subunit OS=Geotrichum candidum GN=BN980_GECA04s07105g PE=3 SV=1
A0A1E4TC63_9ASCO79.570%939.61e-50H/ACA ribonucleoprotein complex subunit OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138713 PE=3 SV=1
A0A1E3PR47_9ASCO76.596%947.45e-49H/ACA ribonucleoprotein complex subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80954 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3478
Predicted cleavage: 25

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 180 200 213

Detailed signature matches

  1. Family IPR007504
    H/ACA ribonucleoprotein complex, subunit Gar1/Naf1
    1. PF04410 (Gar1)
  2. Family IPR021154
    H/ACA ribonucleoprotein complex, subunit Gar1
    1. PD020235
  3. Domain IPR009000
    Translation protein, beta-barrel domain
    1. SSF50447 (Translati...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.10...
  2. mobidb-lite (disord...)

Protein sequence

>MIA_02269_1
MSFRGGRGGGRGGFGGRGGFGGRGAPQQQGPPDRVLEMGTFVHPCEGDIVCKSINTKVPYFNAPIYLENKSVVGKVDEIL
GPINDVYFTIKPAEGIQASSFKTGDKFYIGSDKLLPLERFLPKPKAPAGPKPKRAPGAGGAARGGFGGRGGARGGFGGRG
GARGGFGGSRGGFGGGRGGARGGFGGGRGGARGGFGGSRGGRGGSRGGFGGRR

GO term prediction

Biological Process

GO:0001522 pseudouridine synthesis
GO:0042254 ribosome biogenesis

Molecular Function

None predicted.

Cellular Component

GO:0031429 box H/ACA snoRNP complex