Protein
MCA_06498_1
Length
214 amino acids
Gene name: GAR1
Description: H/ACA ribonucleoprotein complex subunit 1
Browser: contigD:4401567-4402333+
RNA-seq: read pairs 2624, FPKM 150.8, percentile rank 84.9% (100% = highest expression)
Protein function
Annotation: | GAR1 | H/ACA ribonucleoprotein complex subunit 1 | |
---|---|---|---|
KEGG: | K11128 | GAR1 | H/ACA ribonucleoprotein complex subunit 1 |
EGGNOG: | 0PPNM | GAR1 | Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ( psi ) residues may serve to stabilize the conformation of rRNAs |
SGD closest match: | S000001131 | GAR1 | H/ACA ribonucleoprotein complex subunit 1 |
CGD closest match: | CAL0000187800 | GAR1 | H/ACA ribonucleoprotein complex subunit |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_02269_1 | 91.58% | 95 | 9e-58 | MIA_02269_1 |
A0A161HN04_9ASCO | 84.04% | 94 | 6e-53 | H/ACA ribonucleoprotein complex subunit OS=Sugiyamaella lignohabitans GN=GAR1 PE=3 SV=1 |
A0A060TGS1_BLAAD | 81.25% | 96 | 1e-52 | H/ACA ribonucleoprotein complex subunit OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32956g PE=3 SV=1 |
UniRef50_K2QKY0 | 85.87% | 92 | 1e-49 | H/ACA ribonucleoprotein complex subunit n=8 Tax=Eukaryota TaxID=2759 RepID=K2QKY0_MACPH |
A0A0J9X7X6_GEOCN | 82.29% | 96 | 2e-50 | H/ACA ribonucleoprotein complex subunit OS=Geotrichum candidum GN=BN980_GECA04s07105g PE=3 SV=1 |
Q6CAV4_YARLI | 81.52% | 92 | 2e-50 | H/ACA ribonucleoprotein complex subunit OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C24057g PE=3 SV=1 |
GAR1_YEAST | 78.49% | 93 | 2e-49 | H/ACA ribonucleoprotein complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAR1 PE=1 SV=1 |
A0A1E4TC63_9ASCO | 78.72% | 94 | 6e-49 | H/ACA ribonucleoprotein complex subunit OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_138713 PE=3 SV=1 |
A0A1D8PF56_CANAL | 78.26% | 92 | 2e-47 | H/ACA ribonucleoprotein complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GAR1 PE=3 SV=1 |
A0A1E3PR47_9ASCO | 75.27% | 93 | 1e-45 | H/ACA ribonucleoprotein complex subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80954 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8437
Protein family membership
- H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 (IPR007504)
- H/ACA ribonucleoprotein complex, subunit Gar1 (IPR021154)
Domains and repeats
-
Domain
1
20
40
60
80
100
120
140
160
180
200
214
Detailed signature matches
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_06498_1 MSFRGGRGGSRGGRGGFGGGFGNRSAQPQGPPDRVLEMGSFVHPCEGEIVCKSTNTKVPYFNAPIYLENKSLVGKVDEIL GPINDVYFTIKPTEGIQATSFKTGDKFYIGGDKLLPLERFLPKPKAPAGSKPKKSGVNKGGAGRGGFGGRGGARGGSRGG FGGARGGSRGGFGGARGGSRGGFGGGRGGSRGGFSGGRGGSRGGSRGGFGGGRF
GO term prediction
Biological Process
GO:0001522 pseudouridine synthesis
GO:0042254 ribosome biogenesis
Molecular Function
None predicted.
Cellular Component
GO:0031429 box H/ACA snoRNP complex