Protein
MIA_02263_1
Length
1,003 amino acids
Browser: contig03:309669-312752-
Protein function
| EGGNOG: | 0PGE8 | SPT16 | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II |
|---|---|---|---|
| SGD closest match: | S000003175 | SPT16 | FACT complex subunit SPT16 |
| CGD closest match: | CAL0000198046 | CDC68 | FACT complex subunit SPT16 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01906_1 | 74.30% | 922 | 0.0 | MCA_01906_1 |
| A0A0J9X9F6_GEOCN | 68.98% | 922 | 0.0 | Similar to Saccharomyces cerevisiae YGL207W SPT16 Subunit of the heterodimeric FACT complex, which associates with chromatin via interaction with Nhp6Ap and Nhp6Bp OS=Geotrichum candidum GN=BN980_GECA05s01676g PE=4 SV=1 |
| A0A060T472_BLAAD | 58.06% | 937 | 0.0 | ARAD1B00792p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B00792g PE=4 SV=1 |
| A0A1E3PEE3_9ASCO | 55.26% | 950 | 0.0 | SPT16-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_72043 PE=4 SV=1 |
| A0A1E4TG07_9ASCO | 53.80% | 922 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_109297 PE=4 SV=1 |
| UniRef50_A0A1E4TG07 | 53.80% | 922 | 0.0 | Uncharacterized protein n=1 Tax=Tortispora caseinolytica NRRL Y-17796 TaxID=767744 RepID=A0A1E4TG07_9ASCO |
| A0A161HNK7_9ASCO | 60.41% | 773 | 0.0 | Chromatin-remodeling protein SPT16 OS=Sugiyamaella lignohabitans GN=SPT16 PE=4 SV=1 |
| SPT16_YARLI | 53.58% | 935 | 0.0 | FACT complex subunit SPT16 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SPT16 PE=3 SV=1 |
| SPT16_CANAL | 46.28% | 981 | 0.0 | FACT complex subunit SPT16 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC68 PE=3 SV=2 |
| SPT16_YEAST | 46.20% | 961 | 0.0 | FACT complex subunit SPT16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPT16 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0572
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
800
900
1003
Detailed signature matches
-
-
cd01091 (CDC68-like)
-
no IPR
Unintegrated signatures
-
-
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mobidb-lite (disord...)
Residue annotation
-
active site cd01091
Protein sequence
>MIA_02263_1 MSEIKIDRALYNKRIDMIHNALATHRPSLNGADSIFILIGKTDEDNPYHKSAVLHTWLLGYEFPSTALLITKTETIIITS AAKAKYLKDLQSSTLVWTRSKDAEHNNKLFQDLIAKIDEAGNNLGVIQKDKYEGPLVKSWNEIYDASGKKFNEVDVSVAI AELLQLKDEDELRSIRSASKASTGVMTKFLSEEISTIIDEDRKVKHSALSETVESKIEDDNFFKKTLKLNDSLDPSQLDW CYSPNIQSGGKFDLKPSAIPDDNVLYGGVIVTFLGLRYKSYCSNVGRTYLINPTKAQEQNYSFTVALQKKVLETITNGVK ARDVYKAAQDFIKEKNPKLLSHFLKNVGWGTGIEFRDTSLLLNEKNQHVLKDGMTLNLVIGFQDIPNDDAQDGKSKVYSI LLIDTIKVTNGAPEVFTESPKSRGDVSYYFKEEEEAKPVKKEVKKPVKSAILKSKLRGENKSQEDDPEAMRKISQRLFHE KLQKSGLEKYASESSGNSEGTKTTFKRYESYKHLSQLPKDMKDLRIRVDAKNLTILIPINGRLVPFHIAYYKNGSSNEEG EYAYLRLNFNSPGQGVSKKDDIPSEVADAQFIRSITLRSRDGEHIAGVFKKITDLKKEVLKREAEKKEMEDVAPQGKLIE AKNRRPIRLDAVYIRPAPEGKRVNGLIEIHQNGLRYQSPIKSEFNIEILFSNIKHLYFQPCDHELIVIIHAHLKSPIMVG KKKTKDIQIYREATDLAFDETGNRRRRYRYGDEDEVEQEQMERQRRIQLNKEFLKFAEAISDATNGTIDVEIPFRDLGFQ GVPFRSDVLCQPTTESLIQLIDPPFLVITLREIEVVHLERVQFGLRQFDMVVIYKDFSRPVTHINSIPMTQLDAVKDWLN NVEVPYYEGPVNLNWPTIMKTVASDPHQFFKDGGWSFLRLENDGSGQESQESSDEESEFHVSDEDPEDESDIYSEEDSDM SEEDSEGSFGSEEESGEDWDEMDNKAKKLDAKSRGGDDRKRKR
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.