Protein

MIA_02187_1

Length
640 amino acids


Browser: contig03:75445-77368+

Protein function

EGGNOG:0PFXBFG06173.1MATE efflux family protein
SGD closest match:S000002746YDR338CUncharacterized transporter YDR338C
CGD closest match:CAL0000200953orf19.6023Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_06485_170.370%5130.0MCA_06485_1
A0A0J9XE15_GEOCN56.982%6230.0Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily OS=Geotrichum candidum GN=BN980_GECA11s03761g PE=4 SV=1
UniRef50_A0A0J9XE1556.982%6230.0Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XE15_GEOCN
A0A1E3PD01_9ASCO43.678%6091.33e-178MATE efflux family protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_72032 PE=4 SV=1
A0A167D1V8_9ASCO45.359%5711.36e-168Erc1p OS=Sugiyamaella lignohabitans GN=ERC1 PE=4 SV=1
Q6C4J1_YARLI49.251%4671.73e-168YALI0E26345p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26345g PE=4 SV=1
A0A060TAR5_BLAAD48.874%4444.74e-160ARAD1D22022p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22022g PE=4 SV=1
A0A1E4TGI6_9ASCO46.362%4812.20e-154Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44452 PE=4 SV=1
A0A1D8PCB5_CANAL49.558%4521.33e-152Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6023 PE=4 SV=1
YD338_YEAST41.228%4567.63e-124Uncharacterized transporter YDR338C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDR338C PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3100
Predicted cleavage: 58

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF01554 (MatE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. cd13132 (MATE_eukar...)
  3. mobidb-lite (disord...)

Residue annotation

  1. putative cation bi...

Protein sequence

>MIA_02187_1
MSTSNNENSLPVPSARPRRPSETNMSAQFARSPQRDYISFGSVGRPGVFLPTSLPRRSSLIDSMTMEERDELLTQEQELL
ADNKLFQRPPQRKPSLTSVITGRRSSAVGPTYGAFRTKSNTLRVGGEVYGAAGTTSPVPPTESAPLLYPPREEDEEADLN
LGRQMTREESEEIVRETWKEATATGEITTSYKRETAVLLHSSIPVSLAFLLQYSLVVASVFCVGHIGKNELSAVSVAAMV
ANICGYGIFQGLATSLDTLATQAFGRKDYEMVGIHTQQCTLIMLIVAIPIAFVWIFSEPIFEVLVPEKELAVLASQYLQV
LIIGVPGYIVFEVSKHYLQAQGIFHASTYVLIICAPFNLVLNYVLVWNRHIGLGFLGAPIAVITTDYVMAIMSVLYVIYV
DGLQCWHGLSKDSLRNWGHMAKLGLAGVLTLETEWLAFEILTFAAARLGTTELATQTVIATLAVLAYQIPLSMGIAASTR
VGNLVGAQLEQAAVLASNTYIYASVIFGLLNCFLLYFTRHSVGKLFSSDKDVIEMVAYVMPVTALYQVNDCISAVTGGIL
RGQGRQKISGYINLILYYVFALPLGLYLAFNRGYGLRGIWGGIVFALFFVSALQIYFVLTADWKEVIRIAQEDDEEEEED

GO term prediction

Biological Process

GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport

Molecular Function

GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity

Cellular Component

GO:0016020 membrane