Protein
MCA_06485_1
Length
508 amino acids
Browser: contigD:4371971-4373498-
RNA-seq: read pairs 757, FPKM 18.4, percentile rank 39.2% (100% = highest expression)
Protein function
| KEGG: | K03327 | TC.MATE | multidrug resistance protein, MATE family |
|---|---|---|---|
| EGGNOG: | 0PFXB | FG06173.1 | MATE efflux family protein |
| SGD closest match: | S000001074 | ERC1 | Ethionine resistance-conferring protein 1 |
| CGD closest match: | CAL0000200953 | orf19.6023 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02187_1 | 70.10% | 495 | 0.0 | MIA_02187_1 |
| A0A0J9XE15_GEOCN | 53.80% | 487 | 1e-163 | Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily OS=Geotrichum candidum GN=BN980_GECA11s03761g PE=4 SV=1 |
| UniRef50_A0A0J9XE15 | 53.80% | 487 | 2e-160 | Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XE15_GEOCN |
| A0A1E3PD01_9ASCO | 52.59% | 348 | 5e-123 | MATE efflux family protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_72032 PE=4 SV=1 |
| A0A167D1V8_9ASCO | 50.86% | 348 | 7e-120 | Erc1p OS=Sugiyamaella lignohabitans GN=ERC1 PE=4 SV=1 |
| Q6C4J1_YARLI | 51.76% | 340 | 1e-117 | YALI0E26345p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26345g PE=4 SV=1 |
| A0A060T8Q2_BLAAD | 49.72% | 356 | 2e-108 | ARAD1D09042p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09042g PE=4 SV=1 |
| A0A1E4TGI6_9ASCO | 48.50% | 334 | 3e-107 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44452 PE=4 SV=1 |
| A0A1D8PCB5_CANAL | 48.35% | 333 | 1e-104 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6023 PE=4 SV=1 |
| ERC1_YEAST | 43.19% | 345 | 4e-99 | Ethionine resistance-conferring protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERC1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3734
Predicted cleavage: 18
Protein family membership
- Multi antimicrobial extrusion protein (IPR002528)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
cd13132 (MATE_eukar...)
-
mobidb-lite (disord...)
Residue annotation
-
putative cation bi...
Protein sequence
>MCA_06485_1 MSSNNSNNLPIPNRNRNSSENGLSSTIQFARSPQRDYISFGSVGKPGVLLSSASFPKKKTAKLLTQEEREELINQEQELL ADNNLMPPPPKRRASLTSVITGRRSSTSGLTYGAFRSPTTPKPLGPPKRQPSDPTQAHAVNERSALLPPLEAEELSESDE PTTEILTRQRTVEEAWVEATSKGAEINTSYKRETIVLLHSSVPVSLAFLLQYSLVVASVFCVGHLGKTQLSAVSVAAMVA NIIGYGVFQGLATSLDTLATQAYGRKDYAMVGVHTQQCTILMFIVLIPIGLVWIYSRPIFELLVPEKQLALMASQYLQIL IIGAPGYIIFEVSKHFLQAQGIFHASTYILLICAPLNLFLNYILVWNKHIGIGFLGAPVAVITTDYLMALMSILYVVYVD GSQCWTGLSINSLKNWGHMAKLGLAGVLTLETEWLAFEVLTFSAARLGTTELATQTILATVAVLAYQIPLSIGIAASTRV GNLVGAQLEKAAIVASKTYIYASVILDL
GO term prediction
Biological Process
GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport
Molecular Function
GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity
Cellular Component
GO:0016020 membrane