Protein

MIA_02148_1

Length
1,259 amino acids

Browser: contig02:2759601-2763381-

Protein function

EGGNOG:0PHFXFG09930.1Regulator of nonsense transcripts
SGD closest match:S000004685NAM7ATP-dependent helicase NAM7
CGD closest match:CAL0000189066NAM7ATP-dependent RNA helicase

Protein alignments

%idAln lengthE-value
MCA_01149_170.322%9940.0MCA_01149_1
A0A0J9X4W3_GEOCN70.911%8010.0Similar to Saccharomyces cerevisiae YMR080C NAM7 ATP-dependent RNA helicase of the SFI superfamily involved in nonsense mediated mRNA decay OS=Geotrichum candidum GN=BN980_GECA02s06478g PE=4 SV=1
A0A060T9U1_BLAAD66.584%8050.0ARAD1D21626p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D21626g PE=4 SV=1
UniRef50_V5G1X959.585%8190.0Regulator of nonsense transcripts, putative n=1 Tax=Byssochlamys spectabilis (strain No. 5 / NBRC 109023) TaxID=1356009 RepID=V5G1X9_BYSSN
A0A161HJP2_9ASCO63.943%7710.0ATP-dependent RNA helicase NAM7 OS=Sugiyamaella lignohabitans GN=NAM7 PE=4 SV=1
Q5A507_CANAL58.140%8170.0ATP-dependent RNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NAM7 PE=4 SV=1
NAM7_YEAST56.115%8340.0ATP-dependent helicase NAM7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAM7 PE=1 SV=1
Q6C803_YARLI54.890%8180.0YALI0D23881p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D23881g PE=4 SV=1
A0A1E3PP72_9ASCO51.169%8130.0p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81704 PE=4 SV=1
A0A1E4THA5_9ASCO31.540%5392.65e-52Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12256 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0033

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1259

Detailed signature matches

  1. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  2. Domain IPR018999
    RNA helicase UPF1, UPF2-interacting domain
    1. PF09416 (UPF1_Zn_bind)
  3. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. SM00487 (ultradead3)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. PF13086 (AAA_11)
  3. PF13087 (AAA_12)
  4. SSF57850 (RING/U-box)
  5. cd00046 (DEXDc)
  6. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...

Protein sequence

>MIA_02148_1
MITSAPNYYDGDHRVPPPSSTSPSALDLDDSDSDSSVSLVSDPGHHDNHGHSSHSHQLKSLADLLITDFDPPTDEDDLSN
KPACAYCGIDSPSSIVRCVTCNKWFCNARGSSSSSHIINHLVRSRHKVVALHQDSELGETTLECYNCGNQNVFVLGFISA
KAESVIVILCRYPCANTPINKDMNWDSSKWDPLISDRSFTNWLVSVPSQEEVARARKISPVQMTKLEEMWRDSPKATVDD
LDKPDLEQNIPHVVLRYEDGYEYQRCFSPLVMYEADYDRRQKEAQTQSNVSVTWDIGLSRRHLVSFFLQDVDTTGTRVMI
GDVMAIRLDSSVPGVPKWSSTGFVIKIPDSSSEEITLELLIGADPPTNITQDFIINFVWSGVTYERIQSSLKEFATEETS
VSGYLYHKLLGHEVKKIVFNTQLPADFSVPGIAELNPSQSAAVASVLRHPLSLIQGPPGTGKTVVSTTIVYHILKMTKEA
VLVCAPSNVAADQLADRLQRTGLRVVRLVAKSRETILQDADIKSMTLGDIIMNDSDTPEDLRKLQQLKNDVGELSQSDRN
KYFKLLRDAEHRILQHADVVCCTCAAAGDPRLRRVRFRTVLIDESTQATEPECLIPIVHGCKQLVLVGDHQQLGPVVGCK
AAAKAGLAKSLFERLIVLGHTPIRLTVQYRMHPCLSEFPSNIFYDGSLQNGITQQERMRPEINFPWPVPETPMMFWSVLG
KEEISSSGTSYLNRSEASNCERVVTRLFKAGVKPDQIGIITPYEGQRTYLNQHMIINGTMDRELYREVEIESVDAFQGRE
KDYIIVSCVRSNEYQGIGFLSDPRRLNVALTRAKYGLVLLGNPRVLSKNLLWLHLLTHFREKGCLVEGLLSRLQPSNVQL
SKPRQLNTQVFTKFSAAVGTPSNNQSPVAAIDPLLPPQPPNSLIQQISDNRFGESFGPTLQQQYGGSNNALGPIHGSSGS
SSRGGPPPGQRYYNDMLPHDETSSEKDSTLDSDYLHDTESDSGMESSSELESQIGDPLDMGGMPVALSRVAAAAAAATVT
GGSGPTGSLPSSYMLHKHADEIIDDGEETVREYESGPDSDDDDDVISNIRSSRLGPSPNTQPIGSGIPTSVTTNNNSAEV
ERAAKAAAQIFNANAQRAAVINNKRKLKASASSASSVAAQAVEEQRQIGSSFGDRLNQLINKTDSLSVTGSNTNSKSSNG
TLSKSATNSALDLGSSKRGLNIGGGTGIRGQRVLVDDDDDDTDDELESIASFSSQAHLY

GO term prediction

Biological Process

GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Molecular Function

GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding

Cellular Component

GO:0005737 cytoplasm