Protein
MCA_01149_1
Length
1,191 amino acids
Gene name: NAM7
Description: ATP-dependent helicase
Browser: contigA:3647011-3650587+
RNA-seq: read pairs 4811, FPKM 49.9, percentile rank 65.4% (100% = highest expression)
Protein function
| Annotation: | NAM7 | ATP-dependent helicase | |
|---|---|---|---|
| KEGG: | K14326 | UPF1 | regulator of nonsense transcripts 1 [EC:3.6.4.-] |
| EGGNOG: | 0PHFX | FG09930.1 | Regulator of nonsense transcripts |
| SGD closest match: | S000004685 | NAM7 | ATP-dependent helicase NAM7 |
| CGD closest match: | CAL0000189066 | NAM7 | ATP-dependent RNA helicase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02148_1 | 77.08% | 864 | 0.0 | MIA_02148_1 |
| A0A0J9X4W3_GEOCN | 63.75% | 927 | 0.0 | Similar to Saccharomyces cerevisiae YMR080C NAM7 ATP-dependent RNA helicase of the SFI superfamily involved in nonsense mediated mRNA decay OS=Geotrichum candidum GN=BN980_GECA02s06478g PE=4 SV=1 |
| A0A060T9U1_BLAAD | 64.69% | 827 | 0.0 | ARAD1D21626p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D21626g PE=4 SV=1 |
| UniRef50_G2XUQ9 | 56.21% | 886 | 0.0 | Similar to regulator of nonsense transcripts 1 n=7 Tax=Opisthokonta TaxID=33154 RepID=G2XUQ9_BOTF4 |
| A0A161HJP2_9ASCO | 61.49% | 805 | 0.0 | ATP-dependent RNA helicase NAM7 OS=Sugiyamaella lignohabitans GN=NAM7 PE=4 SV=1 |
| NAM7_YEAST | 56.90% | 833 | 0.0 | ATP-dependent helicase NAM7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAM7 PE=1 SV=1 |
| Q5A507_CANAL | 55.40% | 834 | 0.0 | ATP-dependent RNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NAM7 PE=4 SV=1 |
| Q6C803_YARLI | 52.13% | 846 | 0.0 | YALI0D23881p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D23881g PE=4 SV=1 |
| A0A1E3PP72_9ASCO | 50.91% | 827 | 0.0 | p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81704 PE=4 SV=1 |
| A0A1E4THA5_9ASCO | 30.88% | 544 | 3e-57 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12256 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0059
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
200
400
600
800
1000
1191
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
PF13086 (AAA_11)
-
PF13087 (AAA_12)
-
cd00046 (DEXDc)
-
mobidb-lite (disord...)
Residue annotation
-
ATP binding site c...
Protein sequence
>MCA_01149_1 MNRFNNINNSAQESDNVSVTSDVMYQGRYSSDTRQAYDNMENYHKSYDSSDEESISLVSEAGNYDSHHSNNRHLKSLADL LISDMQSAEEEEEMRNAKPMCAYCGIDNPACIVKCVTCNKWFCNTRGGSSSSHIINHLVRSRHKIVQLHPNSELGEYTLE CYNCGAQNVFVLGFIAAKADTVMVILCRYPCANAPAQKEMSWDTSKWTPLIVDRSFSSWLISAPSEEELRMARTITPVQM IKLEEMWRDNPKATIEDLNRPEMENQIPQVSLRYADGYEYQRCFAPLVMHEAEYDRRQKEAQTQSNVSVTWDMGLSRRHL VSFFLPDFETSGIRIMIGDEMAISYEGVDIGVGGTKKLKWESTGFVIKVPSSSSDDVTLELTPNSDPPTHITSGYSIDFV WSGVTYERIQKALKEFATEETSVSGYLYHKLLGHDVKNIVFSHEIPTDFSVPGISALNPSQSAAVSSVLRHPLSLIQGPP GTGKTVVSTTIVYHIQKMTKEAVLVCAPSNVAADQLAVRLSKTGLNVIRLVAKSRETTLRDGEAAGFSEYGQDNAEASLI KNISLGEIIMNDPKTPIELKKLQQLKDDVGELSVSDRKKYFDLLKKAEKRVLQQADVVCCTCAAAGDPRLKKIRFRTVLI DESTQATEPECLIPIVHGCKQLVLVGDHQQLGPVIGCKAVANAGLNRSLFERFIVLGYLPIRLTIQYRMHPCLSEFPSNM FYDGSLQNGITRQERMRPDLNFPWPVPETPMMFWSILGHEEISSSGTSYLNRSEATNCERVVTRLFKAGVKPSQIGIITP YEGQRAYLNQHMLNTGTMDRELYKGVEIESVDAFQGREKDYIIVSCVRSNEHQGIGFLSDPRRLNVALTRAKFGLILLGN PRVLSKNVMWLHLLTHFREKGCLVEGVLSRLQPSSIQLSKPRQPRKRFMNESGDVSQQGYDGYGQQVQQQHHQQSLSRFQ PSNSGKQPPNFQYMNDILPHDETASEHETNLESDFFHESDVSTDAGSDLESQLGDMLDVNGIPSHISNFASLSLNGRGPV GGYAGDDEDSSSDESITSSGTIKSINQHYENHNNFLHGGESNNNNNNNNPIDENLIASATKAFEHNAHVGNNSQGGVTNK NSFITNMKDSKSKKKNNTVVPAGQETRVQDRRIGNSFGDTLNFLLQKREDEDEDSTDEEYESLFTFANQNK
GO term prediction
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
Cellular Component
GO:0005737 cytoplasm