Protein
MIA_02140_1
Length
1,108 amino acids
Browser: contig02:2732274-2735729+
Protein function
| EGGNOG: | 0PGGF | CDC60 | Leucyl-tRNA synthetase |
|---|---|---|---|
| SGD closest match: | S000006081 | CDC60 | Leucine--tRNA ligase, cytoplasmic |
| CGD closest match: | CAL0000201312 | CDC60 | Leucine--tRNA ligase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05555_1 | 79.689% | 1093 | 0.0 | MCA_05555_1 |
| A0A0J9XGU8_GEOCN | 72.536% | 1096 | 0.0 | Similar to Saccharomyces cerevisiae YPL160W CDC60 Cytosolic leucyl tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA15s03090g PE=4 SV=1 |
| A0A060T503_BLAAD | 70.529% | 1096 | 0.0 | ARAD1B04004p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B04004g PE=4 SV=1 |
| A0A1E3PP14_9ASCO | 68.522% | 1096 | 0.0 | Leucyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49613 PE=4 SV=1 |
| Q6C4Q2_YARLI | 67.486% | 1098 | 0.0 | YALI0E24607p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E24607g PE=4 SV=1 |
| A0A167DYF8_9ASCO | 68.631% | 1052 | 0.0 | Leucine--tRNA ligase CDC60 OS=Sugiyamaella lignohabitans GN=CDC60 PE=4 SV=1 |
| A0A1D8PS12_CANAL | 63.579% | 1101 | 0.0 | Leucine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC60 PE=4 SV=1 |
| UniRef50_A0A1X7R4G8 | 62.704% | 1102 | 0.0 | Similar to Saccharomyces cerevisiae YPL160W CDC60 Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7R4G8_9SACH |
| SYLC_YEAST | 62.613% | 1102 | 0.0 | Leucine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC60 PE=1 SV=1 |
| A0A1E4TA44_9ASCO | 59.176% | 1117 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_125746 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0442
Protein family membership
Domains and repeats
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Domain
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Domain
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Domain
1
200
400
600
800
1000
1108
Detailed signature matches
no IPR
Unintegrated signatures
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SSF52374 (Nucleotid...)
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cd00812 (LeuRS_core)
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cd07959 (Anticodon_...)
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mobidb-lite (disord...)
Residue annotation
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active site cd00812
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KMSKS motif cd00812
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tRNA binding surfa...
Protein sequence
>MIA_02140_1 MSAPAAPAPAAKPEAKTIVLENTARRDALIDIEKKYQKIWADEKIFEIDAPQESTLTAAELRAKYPKFMGTMAYPYMNGV LHAGHSFTLSKVEFATGYERLIGKNALFPLGFHCTGMPIKASSDKLIREIELFGENFENAPKDTELDPEPVAAEKKPKED VEKFASKKSKAVAKTGRAKYQFEIMQQLGIPLDEVKKFADPNFWLTYFPPLCQEDCTNFGARVDWRRSFITTDVNPYYDA FVRWQMNRLHESGKIKFGERYTIYSAKDGQPCMDHDRASGEGVGPQEYTGIKIEVKEFPEAAKEALKEVDLSNKKVYLVA ATLRPETMYGQTCCFVSPKITYGLFDAGNNEYFITTERAFKNMCFQKLTPKRGDWSAVTQIPGSSLIGALIDAPLAILKD LRVLPMETVLANKGTGVVTCVPSDSPDDYITTLDLSNKPEYYKIDKDWVKTEPVAIMNTPSYGDLTAKTLVEQLKIRSPK DKDLLTKAKELAYKEGFYQGVMIIGPYKGEKVEVAKPKVKADLIAAGQAFVYNEPEGVVMSRSGDECIVSLEDQWFTDYG EESWKADAAKCLANMNTYSTETRHAFQKVLDWLNNWALSRSYGLGTRIPWDPKFLVESLSDSTIYMAFQAVAHLLQGDFY GKVPGTLGIQPEQMTDEVWDYVLLHKDDIKSDIPKEKLDKLRNEFEYFYPLDVNISGKDLIGNHLTFFIYCHCAIFPEEY WPAGIRANGHLLLNNEKMSKSTGNFMTLKQIVEKFGADASRIALADAGDSLEDANFDETNANAAILRLYNLKEWASEVVK DSDKLRTGPKDSFFDKAFENEINELIAETRKAYDEAFYKVALKYGLFDLQSARDYYRDSTATSGIGMHKDLVLRYIEVQA LLLSPIAPHFCDYLWREVLGHKESIQNARFPEISAPLDKSLTAALEYVRSTQRAIREAEGASMKKKKGKATATTFDPKKP SKLSLYVALSFPEWQEAYIDLVKDAFENLSLDFTPDFRQKVSKLGDVKRGMQFVNYLKMRLTGGGESPDVVFNRKLEFDE SETLKGVVPVLKRAPAATNVEKIELIALDSKDATKGTDILTGEAVVVPTLKAIQDAIPGQPGITLVNL
GO term prediction
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006429 leucyl-tRNA aminoacylation
Molecular Function
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004823 leucine-tRNA ligase activity
GO:0005524 ATP binding
Cellular Component
GO:0005737 cytoplasm