Protein

MIA_02081_1

Length
883 amino acids


Browser: contig02:2540531-2543183+

Protein function

EGGNOG:0PHSNFG01789.1Ferric-chelate reductase
SGD closest match:S000001703FRE2Ferric/cupric reductase transmembrane component 2
CGD closest match:CAL0000201731CFL5Ferric-chelate reductase

Protein alignments

%idAln lengthE-value
MCA_04711_158.501%8940.0MCA_04711_1
A0A060T7K7_BLAAD41.802%6770.0ARAD1C28952p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C28952g PE=4 SV=1
UniRef50_A0A060T7K741.802%6770.0ARAD1C28952p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T7K7_BLAAD
Q6C208_YARLI33.222%5992.56e-106YALI0F11825p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F11825g PE=4 SV=1
A0A1E3PKS3_9ASCO32.285%6041.61e-105Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51285 PE=4 SV=1
A0A0J9XIC4_GEOCN28.547%5928.00e-67Similar to Saccharomyces cerevisiae YOR381W FRE3 Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters OS=Geotrichum candidum GN=BN980_GECA19s01132g PE=4 SV=1
A0A1D8PN52_CANAL27.649%6043.61e-64Ferric-chelate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFL5 PE=4 SV=1
A0A167FY66_9ASCO26.861%6189.90e-63Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1
A0A1E4TJY1_9ASCO25.680%5882.41e-55Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_81144 PE=4 SV=1
FRE2_YEAST26.087%5753.95e-50Ferric/cupric reductase transmembrane component 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3391

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 700 800 883

Detailed signature matches

    1. PF01794 (Ferric_reduct)
    1. SSF63380 (Riboflavi...)
    1. PS51384 (FAD_FR)
    1. PF08022 (FAD_binding_8)
    1. PF08030 (NAD_binding_6)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG01168 (Ferric_...)
  2. SFLDS00052 (Ferric_...)
  3. SSF52343 (Ferredoxi...)
  4. TRANSMEMBRANE (Tran...)
  5. cd06186 (NOX_Duox_l...)

Residue annotation

  1. FAD binding pocket...
  2. FAD binding motif ...
  3. beta-alpha-beta st...
  4. NAD pyrophosphate ...
  5. NAD binding pocket...
  6. NADP ribose bindin...

Protein sequence

>MIA_02081_1
MKIQLALVGFLASPALAMWPNSWIVGNTCEVIAGRNFDNCTSQEHECLCTNQNFLSSVVQCLNDNLSKTSQIDKAWDFVL
NKRCHAPEHASSDEIYKRSLAYLSQKTAVQLNASTKYGDVFTQPIVADRNAIRETYTSIYLNLHNRDVGTWQGSVLVMIW
VVVIGFSGLYRFLRYISVTFAPKSQSMGRPGWITRNYHKHVSIPAAFGHRHIDRYYLFDFIPIFIPTRFESVVISFYTLM
TLIFMCTGYKFQHNNPLWATHYSELVLNVSNRAGIFASIQIPLLTLFALRNSFLIWISGWSFATFNAYHRAISRVTVLLA
IIHAASKHEMMLSFHAPLRLIYYPTMLFRLGVTALVLWSLMILLGFFRVKYYELFLFVHVVGAVASYICILFHLNHVGYK
QTIYVSLAMILGDIVLRVGRILFSNTSLFLKPIEGSKRLTKATLSLLPSDVINVRVRTPIHWPFAPGQYVYIHFNRMNIF
ESHPFSAIGPSSDGESFQLLCKARGGITKRLYDHMLELGANSGEKIEMSVLIEGPYGVHCPVERFDSVILVAGGIGITGI
IPYAEYLALSPQYHEIVLLWTVSSVDELTWIDERLQWLSETGKAKIKLYVTRGGTAPQTKEETRTVMDDGIAMTELDKPV
IVEHPSSFRRHSYETDQMYLVGEGNTKRYSQTGEPGMRRKMSFRKHIKSLSQNSIRVDLDQRMENIDGNEMVDWTDYSTH
HHLRHHSKNGSVFYAQTPISEEDRSTKHNTASTNTAINTAAQTPVESSTPQPYQPGYRYSYTPGKRTSAILAQTATADQK
AGPHSINIQEVIPAQSWMSHVIEGARPNLMETVQEFFRNSTGSVCVVGCGPARMMDTLRRATCVHYDLVVNGRLEYYEEA
FTW

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.