MIA_02076_1

Protein

Length

178 amino acids

Protein function

EGGNOG:	0PPKX	FG01164.1	6,7-dimethyl-8-ribityllumazine synthase
SGD closest match:	S000005503	RIB4	6,7-dimethyl-8-ribityllumazine synthase
CGD closest match:	CAL0000184983	RIB4	6,7-dimethyl-8-ribityllumazine synthase

Protein alignments

	%id	Aln length	E-value
MCA_01027_1	72.94%	170	3e-80	MCA_01027_1
A0A0J9XGY4_GEOCN	68.67%	166	2e-68	6,7-dimethyl-8-ribityllumazine synthase OS=Geotrichum candidum GN=BN980_GECA16s01297g PE=3 SV=1
A0A1E3PIB3_9ASCO	63.79%	174	5e-67	6,7-dimethyl-8-ribityllumazine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46901 PE=3 SV=1
A0A1D8PDK6_CANAL	61.21%	165	1e-62	6,7-dimethyl-8-ribityllumazine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIB4 PE=3 SV=1
A0A060THW1_BLAAD	60.00%	165	2e-61	6,7-dimethyl-8-ribityllumazine synthase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D41206g PE=3 SV=1
RIB4_YEAST	60.00%	165	7e-60	6,7-dimethyl-8-ribityllumazine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIB4 PE=1 SV=2
UniRef50_P50861	60.00%	165	2e-56	6,7-dimethyl-8-ribityllumazine synthase n=80 Tax=Fungi TaxID=4751 RepID=RIB4_YEAST
Q6CH62_YARLI	54.02%	174	1e-56	6,7-dimethyl-8-ribityllumazine synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A12045g PE=3 SV=1
A0A167E1H6_9ASCO	65.75%	73	1e-28	Lumazine synthase RIB4 OS=Sugiyamaella lignohabitans GN=RIB4 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0126

Protein family membership

Lumazine/riboflavin synthase (IPR002180)
- Lumazine synthase (IPR034964)

Domains and repeats

None predicted.

Detailed signature matches

IPR002180

Lumazine/riboflavin synthase
1. G3DSA:3.40.50...
  
  83 - 176
  
  GENE3D
  G3DSA:3.40.50.960 (G3DSA:3.40.50.960)
  
  8 - 82
  
  GENE3D
  G3DSA:3.40.50.960 (G3DSA:3.40.50.960)
2. PF00885 (DMRL_synthase)
  
  22 - 171
  
  Pfam
  PF00885 (DMRL_synthase)
3. SSF52121 (Lumazine ...)
  
  16 - 173
  
  SUPERFAMILY
  SSF52121 (Lumazine synthase)
IPR034964

Lumazine synthase
1. MF_00178 (Lumazine_...)
  
  18 - 176
  
  HAMAP
  MF_00178 (Lumazine_synth)
2. cd09209 (Lumazine_s...)
  
  25 - 170
  
  CDD
  cd09209 (Lumazine_synthase-I)
3. TIGR00114
  
  23 - 171
  
  TIGRFAMs
  TIGR00114 (TIGR00114)

Residue annotation

homopentamer inter...

26G

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

32W

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

61T

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

62T

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

63V

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

64P

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

67Y

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

68E

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

70P

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

71F

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

72G

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

74K

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

75V

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

76L

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

78D

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

87L

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

98K

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

100H

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

101T

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

103H

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

105E

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

106Y

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

108S

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

109D

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

110A

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

112S

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

113H

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

114G

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

116M

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

117R

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

118T

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

119Q

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

120F

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

123G

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

124I

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

128F

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

130L

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

132T

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

134L

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

138Q

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

142R

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

158H

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

161D

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

165A

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

168E

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)

169M

homopentamer interface
26G, 32W, 61T, 62T, 63V, 64P, 67Y, 68E, 70P, 71F, 72G, 74K, 75V, 76L, 78D, 87L, 98K, 100H, 101T, 103H, 105E, 106Y, 108S, 109D, 110A, 112S, 113H, 114G, 116M, 117R, 118T, 119Q, 120F, 123G, 124I, 128F, 130L, 132T, 134L, 138Q, 142R, 158H, 161D, 165A, 168E, 169M
CDD
cd09209 (Lumazine_synthase-I)
active site cd09209

32W

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

33N

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

65G

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

66S

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

67Y

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

68E

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

94G

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

95V

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

96L

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

97I

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

98K

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

99G

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

101T

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

103H

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

104F

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

127V

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

128F

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

129G

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

130L

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

131L

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

142R

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

158H

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

161D

active site
32W, 33N, 65G, 66S, 67Y, 68E, 94G, 95V, 96L, 97I, 98K, 99G, 101T, 103H, 104F, 127V, 128F, 129G, 130L, 131L, 142R, 158H, 161D
CDD
cd09209 (Lumazine_synthase-I)

Protein sequence

>MIA_02076_1
MAETTTQIKGLGDLDKSYDGSKLRVGIVHARWNDKVIAALVAGAKAKLAAMGVPESNVVVTTVPGSYELPFGTKVLYDAH
KGKETELDVIISIGVLIKGHTMHFEYISDAVSHGLMRTQFDLGIPVVFGLLTCLSEEQALERSGLVVNEEGASHSHNHGE
DWGAAAVEMAYKNKYHVL

GO term prediction

Biological Process

GO:0009231 riboflavin biosynthetic process

Molecular Function

GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity

Cellular Component

GO:0009349 riboflavin synthase complex

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Entry type

Status

Per-residue features