Protein

MIA_02068_1

Length
524 amino acids

Browser: contig02:2507310-2508939-

Protein function

EGGNOG:0PMCNISC1phospholipase C
SGD closest match:S000000821ISC1Inositol phosphosphingolipids phospholipase C
CGD closest match:CAL0000175369ISC1Inositol phosphosphingolipid phospholipase

Protein alignments

%idAln lengthE-value
MCA_03872_164.272%5150.0MCA_03872_1
A0A167FEM2_9ASCO50.685%5117.89e-152Inositol phosphosphingolipid phospholipase OS=Sugiyamaella lignohabitans GN=ISC1 PE=4 SV=1
A0A0J9XDQ1_GEOCN65.257%3312.53e-143Similar to Saccharomyces cerevisiae YER019W ISC1 Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide OS=Geotrichum candidum GN=BN980_GECA11s00494g PE=4 SV=1
UniRef50_A0A0J9XDQ165.257%3315.17e-140Similar to Saccharomyces cerevisiae YER019W ISC1 Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XDQ1_GEOCN
A0A1E3PNA9_9ASCO61.184%3044.43e-119DNase I-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_23006 PE=4 SV=1
Q6C8M5_YARLI55.629%3027.14e-110YALI0D18458p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D18458g PE=4 SV=1
A0A060T926_BLAAD52.978%3196.61e-103ARAD1C34628p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C34628g PE=4 SV=1
A0A1E4TBC1_9ASCO47.452%3141.13e-85Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_27014 PE=4 SV=1
ISC1_YEAST43.626%3534.23e-82Inositol phosphosphingolipids phospholipase C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ISC1 PE=1 SV=1
A0A1D8PT33_CANAL43.161%3296.43e-78Inositol phosphosphingolipid phospholipase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ISC1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0115

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 524

Detailed signature matches

  1. Domain IPR005135
    Endonuclease/exonuclease/phosphatase
    1. SSF56219 (DNase I-like)
    2. PF03372 (Exo_endo_phos)
    3. G3DSA:3.60.10.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MIA_02068_1
MSDYELSDIPVISPSSDASHVVARILSLNCWGLKYVSKFRAERLAAIAERIAAAGDRYDIVALQEIWVEADYELIRAVTA
PHFRYHKYFYSGILAGPGLLVLSKWPIESASLFRYPLNGRPSAFFRGDWYVGKSAASVVIRPIIQHSSSTAAASSTTTAV
QEVEARPIEILSTHLHAPYGPGDAAYTCHRTAQAWELARLARRASQLGHEVVVLGDLNSIPGSLSHRLFQHTAGLRDSWQ
DLHGEFEGGPEAMGQLTPEDQIALAGTTCDSQLNTWRADRQRHEAKRLDYIFYDPKYASPADCRVAFVEPIAGIGSVSDH
FAVEASLIISNIVNGAATASPNPFASNLNLRAAATAASSGANMAASPQSSISSLEPPPQLQQLSNRRSGLQHNLSYAPPG
NGAPGSIHKVQTTTSSATRDELRLLYSDILELIEEYKPTSIIQARLRNYHFIASVIVLIGILIAVWWGAAHNRAYVGFIF
ILVTIAVAVTGLLDGLIGFLFGRNEWRALLEFQSEVELELHFLG

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.