Protein

MIA_02030_1

Length
645 amino acids


Browser: contig02:2395742-2397680+

Protein function

EGGNOG:0PJ6RFG06174.1disulfide isomerase
SGD closest match:S000001267EPS1ER-retained PMA1-suppressing protein 1
CGD closest match:CAL0000180758orf19.1392Protein disulfide isomerase

Protein alignments

%idAln lengthE-value
MCA_00860_154.893%6540.0MCA_00860_1
A0A0J9XIP9_GEOCN44.822%6761.76e-179Similar to Saccharomyces cerevisiae YIL005W EPS1 ER protein with chaperone and co-chaperone activity,involved in retention of resident ER proteins OS=Geotrichum candidum GN=BN980_GECA20s00560g PE=4 SV=1
UniRef50_A0A0J9XIP944.822%6763.60e-176Similar to Saccharomyces cerevisiae YIL005W EPS1 ER protein with chaperone and co-chaperone activity,involved in retention of resident ER proteins n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIP9_GEOCN
A0A167FWW9_9ASCO36.076%6326.54e-112Protein disulfide isomerase EPS1 OS=Sugiyamaella lignohabitans GN=EPS1 PE=4 SV=1
A0A060T8M7_BLAAD27.814%6221.51e-71ARAD1D08382p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D08382g PE=4 SV=1
Q6C7A3_YARLI27.949%5511.31e-64YALI0E02420p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E02420g PE=4 SV=1
A0A1E4TBH3_9ASCO31.887%4617.91e-50Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32396 PE=4 SV=1
A0A1E3PFI4_9ASCO26.246%6824.33e-45Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83739 PE=4 SV=1
EPS1_YEAST26.882%2792.47e-16ER-retained PMA1-suppressing protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EPS1 PE=1 SV=1
A0A1D8PII5_CANAL27.193%2287.35e-16Protein disulfide isomerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1392 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4832

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 645

Detailed signature matches

    1. SSF52833 (Thioredox...)
    1. PF00085 (Thioredoxin)
    2. PS51352 (THIOREDOXIN_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF13848 (Thioredoxin_6)
  2. SFLDG00345 (PDI-like)
  3. TRANSMEMBRANE (Tran...)
  4. cd02961 (PDI_a_family)
  5. mobidb-lite (disord...)

Residue annotation

  1. catalytic residues...

Protein sequence

>MIA_02030_1
MKSLIRIHSALATLLFMLVTFAVAAPSKGVDVSKTPQELVLEDIPDKISQGFWWIKFYSPYCHHCKAFAPTWDRVYKKLN
SSYEELHFASVNCVTQGDLCQKMDIGVYPTINLYKNGNVVKNMKGIQEEDFLESFIDKEILKARDEAQNPEKPSESTAEP
TKSRDSKFPAYPDSSDVVNSEYPESIDPELLEDTADPSLPNPNGISVNLDLSDFSRLVTAKRDGWFIQFYSTDSKYTRNI
QPAWDLMAAEAKGKVNIGQVNCKLERRLCKEAGITQFPTLKYFASSMQSEYKGLRGTGDLLQFLKRAYDSHRPKNISFKE
YSVIRKDAEDVTLLYLFNHNTATEDFQAFEKLAVSVIGTVDVAISNDTNIIKDLKEDNLPALYAISKEKKVRFPEKTSYG
LRDHNQLVRWAEKNRQPLVPQLTPSNVKDIFGNSMVILAILDPREEEITTSSIKELKAAAMEIQEIMAKNEREELEELRK
KKQLKIDEAKDKDDKGAEERANEIRVEVADREPISVAWIDAIFWERWLKGRYGPYAEARVIINDERGGKYWDRTVGGDIL
KPSRSSILETLEDITSPNSKIKPVSLHNSVLVYISETKDNVIANKGFYLTVVAIILFAVWYTRHYSSPSRKYNSLPSEGL
LGKQD

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis

Molecular Function

None predicted.

Cellular Component

None predicted.