Protein

MIA_01994_1

Length
1,097 amino acids

Browser: contig02:2296475-2299769-

Protein function

EGGNOG:0PRE9IPPc
SGD closest match:S000005050INP52Polyphosphatidylinositol phosphatase INP52
CGD closest match:CAL0000196862orf19.7052Phosphatidylinositol-3-/phosphoinositide 5-phosphatase

Protein alignments

%idAln lengthE-value
A0A161HFS7_9ASCO35.77%7522e-135Phosphoinositide 5-phosphatase INP51 OS=Sugiyamaella lignohabitans GN=INP51 PE=4 SV=1
UniRef50_A0A161HFS735.77%7527e-132Phosphoinositide 5-phosphatase INP51 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HFS7_9ASCO
MCA_02503_148.75%4806e-136MCA_02503_1
A0A0J9XHK1_GEOCN47.30%4631e-114Similar to Saccharomyces cerevisiae YIL002C INP51 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase OS=Geotrichum candidum GN=BN980_GECA17s01638g PE=4 SV=1
A0A060T5E8_BLAAD38.63%4539e-84ARAD1C11594p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11594g PE=4 SV=1
A0A1E3PM36_9ASCO32.73%4432e-59DNase I-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_65059 PE=4 SV=1
Q6CGP2_YARLI30.38%4971e-49YALI0A17578p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A17578g PE=4 SV=1
A0A1D8PQN8_CANAL31.79%1516e-19Phosphatidylinositol-3-/phosphoinositide 5-phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7052 PE=4 SV=1
A0A1E4TLY1_9ASCO34.42%1544e-16Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_92605 PE=4 SV=1
INP52_YEAST33.33%1711e-13Polyphosphatidylinositol phosphatase INP52 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=INP52 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0026

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1097

Detailed signature matches

  1. Domain IPR005135
    Endonuclease/exonuclease/phosphatase
    1. SSF56219 (DNase I-like)
    2. G3DSA:3.60.10.10
  2. Domain IPR000300
    Inositol polyphosphate-related phosphatase
    1. SM00128 (i5p_5)
  3. Domain IPR013783
    Immunoglobulin-like fold
    1. G3DSA:2.60.40.10
  4. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.55...
  2. mobidb-lite (disord...)

Protein sequence

>MIA_01994_1
MHTLETSSHILQLFPVPREPYYALVDRARPTDYSIVPLTANTVLAAQPTSATTTTSGTSVDDSDIHLVLDGLPIGDVPAT
SPAALADFMLYWKEAISSLSVNSSKAGITPQSQVTLESPQSQAAPPAEAMKTSLIRNIEPLKTTFLEDRKLKIRAISWNI
HAEPLTKADIHSLLGLPEPFDLYILAIQESDQLGPKNLYANQTTLSATQEYLVQTLGGPKKYQIVAANQLLGIMLLVVAA
TPLIPHLSAFSQNTTGTGIFGIWGNKGAAVVSFYVGQDLAVGLEGTHISILNCHLAHGEGIQGIERRRWELSEIQKKLNI
NGLIGKRAPMLIFSGSHDKEEKESNPKETKAETAEESKENPKEEEEKKDDSTKEKKEEDNDSIIVKGDEDSIIAKDNDSI
SDEDLESLPPVPIAAPMIDSLPEPEPESTPSVTIVLGDLNYRVALDPVVVQDLVEQEDYETILTHDRLIVEHESKRLLPR
FSEAPIKFPPTYKYVVGTDDFDDTKQPASATASGIKRARAPSYTDRIFFASEHTSEPCTATKYESLMEYTMSDHKPVAAN
LEVVVKTVDPEKRRVAVSKILKESDDRENLSKPTVTVTPREVAVDDALVLRPAEATVALKYQPNEKAPNKVLHWQISLAP
DAPPGDAYGAEAAFVSGAVSASTPVSIWPLKGVLPPGATQYIKFGCTLPIAKGTSTVSRVAVLNIIDTQDIFVPVEFRAL
PTSLGTSLDVLSRLPKGARSGTATMSTDDAGANMPKEIWSCVDYLWQNVDLLFAEPHKKLMWEDALANAEPSLQLQVQEW
LDLGEDFDTVVLAAANAIVKPGMPLTSQSNLGLYSVAAQFLLLLENLDGGVVPVEYYPLVLHGREGALQALERVPRVNVN
VLLYLASFLKLLLDKEQQANEARAQKKVVVNAAPDATSTTPPTVANTASLSAPVTETPAAAVAQETDKKKEPQTRPKSRS
VSERFASSLGDFGHNALGAVTAVGTAVGNGVVEAGHGVVDAGKGVGTAVTSGLSNLKLPLTSTAGASSGVGEVSDATAEI
KLVDNSDKEEPVRIDAGRARAMLSFFEEYVIARPAGLKDTKAAKNARVDFLAELVGV

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0046856 phosphatidylinositol dephosphorylation

Molecular Function

None predicted.

Cellular Component

None predicted.