Protein

MCA_02503_1

Length
1,010 amino acids

Description: inositol polyphosphate 5-phosphatase

Browser: contigB:1491529-1494562-

RNA-seq: read pairs 1829, FPKM 22.4, percentile rank 44.3% (100% = highest expression)

Protein function

Annotation:inositol polyphosphate 5-phosphatase
KEGG:K01099INPP5B_F inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
EGGNOG:0PRE9IPPc
SGD closest match:S000005050INP52Polyphosphatidylinositol phosphatase INP52
CGD closest match:CAL0000196862orf19.7052Phosphatidylinositol-3-/phosphoinositide 5-phosphatase

Protein alignments

%idAln lengthE-value
MIA_01994_148.36%5192e-148MIA_01994_1
A0A0J9XHK1_GEOCN44.32%5282e-124Similar to Saccharomyces cerevisiae YIL002C INP51 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase OS=Geotrichum candidum GN=BN980_GECA17s01638g PE=4 SV=1
UniRef50_A0A0J9XHK144.32%5284e-121Similar to Saccharomyces cerevisiae YIL002C INP51 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHK1_GEOCN
A0A060T5E8_BLAAD35.37%5237e-90ARAD1C11594p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C11594g PE=4 SV=1
A0A161HFS7_9ASCO35.26%5536e-85Phosphoinositide 5-phosphatase INP51 OS=Sugiyamaella lignohabitans GN=INP51 PE=4 SV=1
Q6CGP2_YARLI30.52%5576e-57YALI0A17578p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A17578g PE=4 SV=1
A0A1E3PM36_9ASCO28.73%5436e-58DNase I-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_65059 PE=4 SV=1
A0A1D8PQN8_CANAL32.90%1558e-19Phosphatidylinositol-3-/phosphoinositide 5-phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7052 PE=4 SV=1
A0A1E4TLY1_9ASCO33.99%1539e-17Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_92605 PE=4 SV=1
INP52_YEAST33.99%1532e-15Polyphosphatidylinositol phosphatase INP52 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=INP52 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0038

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1010

Detailed signature matches

  1. Domain IPR005135
    Endonuclease/exonuclease/phosphatase
    1. SSF56219 (DNase I-like)
    2. PF03372 (Exo_endo_phos)
    3. G3DSA:3.60.10.10
  2. Domain IPR000300
    Inositol polyphosphate-related phosphatase
    1. SM00128 (i5p_5)
  3. Domain IPR013783
    Immunoglobulin-like fold
    1. G3DSA:2.60.40.10
  4. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  5. Domain IPR000198
    Rho GTPase-activating protein domain
    1. SM00324 (RhoGAP_3)
    2. PS50238 (RHOGAP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.55...
  3. mobidb-lite (disord...)

Protein sequence

>MCA_02503_1
MYSLETSSHILQLFAVPGDPYYALIDRSRPTDYSINPLSSTSCFITTEANDNEISIFLNNIPIGQISTTNPSPLADFLTF
WRQAISTLPNVSTSVITNKNQLRHLIPSSLTSLNNTILNTLDPSSYVSSEESPASKVEALKTNLVTNIAPLIPTFVNKCP
LTFRFITWNIHAEPISKTNISSLLGLPDKRYDMYVLALQESDELGPKNLYANHTTLESTKEYLVQTLGGPKDYEVVAWNQ
LLGIMMIVVVNTKLSPHLSNFSMATTATGLLGLWGNKGAAMVSFYIGQDLTLGISGTKISILNCHLTHGESFQSTDRRRW
ELSEIQRKLNIPGLVGSPQTVVLFNNNKDDDALSLSTKNDSKPDLSATSSVDDLGTTKHVSMESLSLKSEKIDEESEDDD
NIIFHSDDESSDSGKTEREPSEEKKDEQKKDESTNNSKDEKKDEKDEKDDEKKEDKQEEKKEEDMTISVLPSRTPIASAI
KSPKPDDRLIFVVGDFNYRVNLDPDVVVNLAEHNDFETIVAQDRLLLERAQQSVLSDYEEGEINFPPTYKYSIGTDDYDD
TKLPAEDKKMKARTPSYTDRIFFSRNEGLKLEKYTSLMEYTLSDHKPVVADFVYDASLIDEEKRKDAISKVLKESDDKEN
MSKPNIIVSPRDVVVKDAIVMKESEAVISIEHVPSATNPDQEKVLYWELSLAPATNNNSTTSLVSNEEEEGTEKHSEVQD
SNLLFKDIQKNVQDDSSLTIYPTRGALPPVAKQYIHIKCTLPIQRGISRLSRVAVLRIVDTQDIFIPIEFVSLPTCLGTS
LEVLSRFKGGARKGAQAMLDDASNNMPKEIWSCVDYVWQHIDLLPHRSQYKRGKEDGLFTENTPKYAEASLKFQIQEWLD
NDEEFDTVVLDTANQLMSGIPVGVYSVLDQFLLFLRHLDGKIIPYEYYSTIVLKGRMGANLILERIPRANVNVLLYLMSF
LKLLIDEEKIYPDPLLAFFDPLIIQQPTVVRDSRANKYARMEFLKELVGI

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0046856 phosphatidylinositol dephosphorylation

Molecular Function

None predicted.

Cellular Component

None predicted.