Protein

MIA_01913_1

Length
450 amino acids


Browser: contig02:2056409-2057762-

Protein function

EGGNOG:0PH6DPGUG_00255Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate (By similarity)
SGD closest match:S000004666ARG7Arginine biosynthesis bifunctional protein ArgJ, mitochondrial
CGD closest match:CAL0000177240ECM42Arginine biosynthesis bifunctional protein ArgJ, mitochondrial

Protein alignments

%idAln lengthE-value
MCA_02554_182.110%4360.0MCA_02554_1
A0A0J9X3T5_GEOCN77.376%4420.0Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Geotrichum candidum GN=BN980_GECA02s00604g PE=3 SV=1
A0A161HGT5_9ASCO70.023%4370.0Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Sugiyamaella lignohabitans GN=ARG7 PE=3 SV=1
ARGJ_YARLI63.864%4400.0Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0E13057g PE=3 SV=1
A0A1E3PKI2_9ASCO65.402%4480.0Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51206 PE=3 SV=1
A0A060T1A3_BLAAD66.268%4180.0Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18590g PE=3 SV=1
A0A1E4TKL9_9ASCO62.945%4210.0Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_23508 PE=3 SV=1
ARGJ_CANAL63.551%4280.0Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ECM42 PE=3 SV=1
UniRef50_A0A0F8BSE358.057%4531.63e-173Arginine biosynthesis bifunctional protein ArgJ, mitochondrial n=2 Tax=leotiomyceta TaxID=716546 RepID=A0A0F8BSE3_CERFI
ARGJ_YEAST55.581%4301.63e-157Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARG7 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9850
Predicted cleavage: 48

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 450

Detailed signature matches

    1. MF_01106 (ArgJ)
    2. PF01960 (ArgJ)
    3. cd02152 (OAT)
    1. SSF56266 (DmpA/ArgJ...)
Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. heterotetramer int...
  2. active site pocket...
  3. cleavage site cd02...

Protein sequence

>MIA_01913_1
MLSSSFKQASRALQATRFFSSSSARLTAPDKSRFVPKSGVYPKGFRVGGYYSGVKKRPELLDLAAIVSDIPAAASAVFTT
NVFRAAPVQISKKVLDETHGEGINAIIINSGCANAVTGEGGLQDATTMVQLVDKTLEKPAPSGIIAKSLVMSTGVIGQHL
KMDKIEAGIPELLTKHLGSDHESWLRGAKAICTTDTFPKLVSKEFSIGSNTYRIAGLAKGAGMIHPNMATLLGFFVTDAA
VEPAALKSILKYAADRSFNSISVDGDTSTNDTIAALANGAAGGPVITEGSEGYQILRDAITSFAISLAQLVVRDGEGATK
FITIKIEDAKTFEDAKKVASTIATSPLVKTAMFGKDANWGRILCATGYAGVEVDPAKTNVSFIPNDGSAELKLLVNGEPE
NVDEARASQLLDEEDVNIRVSLGTGGGHSTEYWTCDFSHEYVTINGDYRT

GO term prediction

Biological Process

GO:0006526 arginine biosynthetic process

Molecular Function

GO:0004358 glutamate N-acetyltransferase activity

Cellular Component

None predicted.