MIA_01903_1

Protein

Length

1,579 amino acids

Browser: contig02:2027689-2032429+

Protein function

EGGNOG:	0PH07	FG07466.1	P-type ATPase
SGD closest match:	S000005817	YPK9	Vacuolar cation-transporting ATPase YPK9
CGD closest match:	CAL0000199066	orf19.1573	Cation-transporting ATPase

Protein alignments

	%id	Aln length
MCA_00962_1	66.710%	1538	MCA_00962_1
A0A0J9XDC9_GEOCN	59.789%	1425	Cation-transporting ATPase OS=Geotrichum candidum GN=BN980_GECA11s02639g PE=3 SV=1
UniRef50_A0A0J9XDC9	59.789%	1425	Cation-transporting ATPase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDC9_GEOCN
A0A060TCR2_BLAAD	51.640%	1555	Cation-transporting ATPase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D44946g PE=3 SV=1
A0A167ELY3_9ASCO	52.591%	1428	Cation-transporting ATPase OS=Sugiyamaella lignohabitans GN=YPK9 PE=3 SV=1
Q6C829_YARLI	50.585%	1453	Cation-transporting ATPase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D23265g PE=3 SV=1
A0A1E3PRX7_9ASCO	47.328%	1572	Cation-transporting ATPase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_72594 PE=3 SV=1
A0A1E4TJW5_9ASCO	45.075%	1391	Cation-transporting ATPase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30324 PE=3 SV=1
A0A1D8PGL4_CANAL	43.882%	1463	Cation-transporting ATPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1573 PE=3 SV=1
YPK9_YEAST	48.099%	1289	Vacuolar cation-transporting ATPase YPK9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPK9 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0053

Protein family membership

P-type ATPase (IPR001757)
- P-type ATPase, subfamily V (IPR006544)

Domains and repeats

Domain
519 - 612
P-type ATPase, transmembrane domain (IPR023298)
751 - 848
P-type ATPase, transmembrane domain (IPR023298)
1,324 - 1,533
P-type ATPase, transmembrane domain (IPR023298)
Domain
613 - 753
P-type ATPase, A domain (IPR008250)
794 - 1,145
HAD-like domain (IPR023214)
P-type ATPase, cytoplasmic domain N (IPR023299)
1,250 - 1,327
HAD-like domain (IPR023214)

1 200 400 600 800 1000 1200 1400 1579

Detailed signature matches

IPR001757

P-type ATPase
1. TIGR01494
  
  1,250 - 1,355
  
  TIGRFAMs
  TIGR01494 (TIGR01494)
  
  768 - 879
  
  TIGRFAMs
  TIGR01494 (TIGR01494)
IPR006544

P-type ATPase, subfamily V
1. PF12409 (P5-ATPase)
  
  340 - 495
  
  Pfam
  PF12409 (P5-ATPase)
2. TIGR01657
  
  343 - 1,523
  
  TIGRFAMs
  TIGR01657 (TIGR01657)
IPR023298

P-type ATPase, transmembrane domain
1. SSF81665 (Calcium A...)
  
  1,324 - 1,533
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  
  519 - 612
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  
  751 - 848
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
IPR008250

P-type ATPase, A domain
1. SSF81653 (Calcium A...)
  
  613 - 753
  
  SUPERFAMILY
  SSF81653 (Calcium ATPase, transduction domain A)
IPR023214

HAD-like domain
1. SSF56784 (HAD-like)
  
  1,250 - 1,327
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  
  850 - 865
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  
  1,057 - 1,145
  
  SUPERFAMILY
  SSF56784 (HAD-like)
IPR023299

P-type ATPase, cytoplasmic domain N
1. G3DSA:3.40.11...
  
  794 - 1,105
  
  GENE3D
  G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
IPR018303

P-type ATPase, phosphorylation site
1. PS00154 (ATPASE_E1_E2)
  
  856 - 862
  
  PROSITE patterns
  PS00154 (ATPASE_E1_E2)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

1,469 - 1,479

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,536 - 1,579

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

595 - 767

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

378 - 548

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

827 - 1,337

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1,382 - 1,401

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
Coil

246 - 273

COILS
Coil (Coil)
G3DSA:1.20.11...

1,235 - 1,539

GENE3D
G3DSA:1.20.1110.10 (G3DSA:1.20.1110.10)
G3DSA:2.70.15...

514 - 755

GENE3D
G3DSA:2.70.150.10 (G3DSA:2.70.150.10)
NON_CYTOPLASM... (N...)

1 - 356

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,498 - 1,516

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

789 - 799

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,425 - 1,448

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

1,357 - 1,361

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

569 - 573

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
PF00122 (E1-E2_ATPase)

613 - 834

Pfam
PF00122 (E1-E2_ATPase)
PF00702 (Hydrolase)

1,024 - 1,144

Pfam
PF00702 (Hydrolase)
PR00119 (CATATPASE)

1,277 - 1,296

PRINTS
PR00119 (CATATPASE)

659 - 673

PRINTS
PR00119 (CATATPASE)

854 - 868

PRINTS
PR00119 (CATATPASE)
PS01229 (COF_2)

1,277 - 1,299

PROSITE patterns
PS01229 (COF_2)
TMhelix

1,481 - 1,498

TMHMM
TMhelix (TMhelix)

356 - 378

TMHMM
TMhelix (TMhelix)

807 - 829

TMHMM
TMhelix (TMhelix)

549 - 571

TMHMM
TMhelix (TMhelix)

1,364 - 1,381

TMHMM
TMhelix (TMhelix)

575 - 594

TMHMM
TMhelix (TMhelix)

1,402 - 1,424

TMHMM
TMhelix (TMhelix)

1,337 - 1,359

TMHMM
TMhelix (TMhelix)

768 - 787

TMHMM
TMhelix (TMhelix)

1,449 - 1,468

TMHMM
TMhelix (TMhelix)

1,513 - 1,532

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

1,362 - 1,381

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,449 - 1,468

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

768 - 788

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

549 - 568

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,517 - 1,535

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,338 - 1,356

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,480 - 1,497

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

1,402 - 1,424

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

800 - 826

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

357 - 377

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

574 - 594

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
cd07542 (P-type_ATP...)

525 - 1,447

CDD
cd07542 (P-type_ATPase_cation)
mobidb-lite (disord...)

263 - 285

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 171

MobiDB Lite
mobidb-lite (disorder_prediction)

430 - 472

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

phosphorylation si...

856D

phosphorylation site
856D
CDD
cd07542 (P-type_ATPase_cation)
P-type ATPase sign...

856D

P-type ATPase signature motif
856D, 857K, 858T, 859G, 860T, 861L, 862T
CDD
cd07542 (P-type_ATPase_cation)

857K

P-type ATPase signature motif
856D, 857K, 858T, 859G, 860T, 861L, 862T
CDD
cd07542 (P-type_ATPase_cation)

858T

P-type ATPase signature motif
856D, 857K, 858T, 859G, 860T, 861L, 862T
CDD
cd07542 (P-type_ATPase_cation)

859G

P-type ATPase signature motif
856D, 857K, 858T, 859G, 860T, 861L, 862T
CDD
cd07542 (P-type_ATPase_cation)

860T

P-type ATPase signature motif
856D, 857K, 858T, 859G, 860T, 861L, 862T
CDD
cd07542 (P-type_ATPase_cation)

861L

P-type ATPase signature motif
856D, 857K, 858T, 859G, 860T, 861L, 862T
CDD
cd07542 (P-type_ATPase_cation)

862T

P-type ATPase signature motif
856D, 857K, 858T, 859G, 860T, 861L, 862T
CDD
cd07542 (P-type_ATPase_cation)
putative ATP bindi...

856D

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

857K

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

858T

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,004F

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,034K

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,035G

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,036A

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,068I

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,129T

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,130G

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,131D

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,254R

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,257P

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,260K

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,279D

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)

1,282N

putative ATP binding site
856D, 857K, 858T, 1,004F, 1,034K, 1,035G, 1,036A, 1,068I, 1,129T, 1,130G, 1,131D, 1,254R, 1,257P, 1,260K, 1,279D, 1,282N
CDD
cd07542 (P-type_ATPase_cation)
putative cation bi...

1,336K

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

1,340L

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

1,341Y

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

1,343A

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

1,344I

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

1,360G

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

1,363Q

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

1,364F

putative cation binding site
1,336K, 1,340L, 1,341Y, 1,343A, 1,344I, 1,360G, 1,363Q, 1,364F
CDD
cd07542 (P-type_ATPase_cation)

Protein sequence

>MIA_01903_1
MSPSGSQNYPLGRDENPAPYSPRISHHGHHTSRRRSTSVATNRSEAIDTDWDEEDEYLAEPASEEIFSGPVSESVPSAYS
SFHHRRYSSRQPSISRRDSSVDRHAPPSADNVEGEMASSMGSRHSFSFFRAGSVTSQSNLPPPDSAIGETEGSLDNRRDS
MASLSSEISFRHRSEPNNASFRFFSQDEIEHAESASTVPNEVDPVEYEILRRENEEYNPEDDVSDYITRTPHQHPSRYAY
EDTSVLLRHEAEIELARDELEFAEENEQEESAIENGDAAATRSVYSRRRSSDNHLNRWTTHDSNEPLLLSRINSQISPQP
TPKKYSSSSNSQQRFYISEEDMVIVIAGYSSSKMRAALYYALCICTLGMAYLILRWIPRWHIACLGKPVPLGQCDWVVVE
NQWGELSIINVNSFYFNRPMSHVFRLKNPEKEPERTAEVSNGSSTAGSGNIQASQGLNTPANRNYDTDGEDEYQEDPILH
TLRSIEYRYIKFYYNPQEDIFLTNYDWVDPSWTGTERVREGIEPETQAERKLIFGPNLIDIKEKTTVELLVDEILHPFYV
FQVFSMLLWAFDEYYYYATCILFISVISVGNTLIETKQTMRRLREISRYVSDIRVLRSGYWITILSSELMPGDIYEVSDP
SISIFPCDSLLLSGDCVVNESMLTGESVPVSKYPITENALKSFVNGPSQGSSVPADVTKHFLFSGTKVVQVRRPVAQNTD
SRNGNSSFDQLDVAVAMVVRTGFMTTKGSLVRSMLFPKPSGFKFYQDSFKYIGVMAFVAVLGFSYSIFDFIKMHMATKLI
IFRALDLITIVVPPALPATLTIGTNISLSRLRKKKIFCISPSRVNVGGKLDIVCFDKTGTLTEDGLDVLGLHVQENGRFS
DLLQSIEDVFPFSDLDFEEPIPGKTNGGIMKNSKLSKHQRSSFVAALTTCHLLRKIDGEMLGDPLDFKMFSFTGWDFEEE
GGAKLFAADYTHEYPVPISCPPTTNEAKFSLPSNTLGTILSFDFVPRLRRMSVLVKSLGSSGANDTTNIYAYVKGAPEIM
PEVCDPSTFPEDYDDLLYQYTHRGYRVIACATKTYTDLSTADARKLKREEVESGLKFLGFIVFENRLKPTTTRAIEQLNE
AHIRTVMCTGDNVLTAISVAKECHMVSENTKIFVPRFEQLPDGVSPDEFNPISWEYIDDRQLQLDPVTFQPFFVPENGEI
NAQTERNFQQVHHYQEFGFDYALAVTGDAFRYIVQFGRDRQLEFVLMKGAIFARMSPDEKHELVEKLQSLDYTTGFCGDG
ANDVGALKAADVGISLSEAEASVAAPFTSQVFEISCVLDVISEGRSALVTSFSCFKYMSLYSAIQFITVSILYSLGSNLG
DFQFLWIDLFLILPIAIVMAWSEPYPTLSIKRPTANLVSPKILVPLLGQIVILALFQLGIWHAVRKEPYYVPPVMGGDDE
DVDSTDNTALFFFSSYQYIFVSILLTVGPPYHEPIIKNRPFVITIIATCMLTGSFMLVPADTGLGQFMNLTDISTNFKLI
ILITVLINFFVCKFFEDRVFLPLAVFLRRLCVMLKLPAKTVSNKLYKRIVKAMEHHKQA

GO term prediction

Biological Process

GO:0006812 cation transport

Molecular Function

GO:0000166 nucleotide binding
GO:0016887 ATPase activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features