Protein
MIA_01901_1
Length
1,286 amino acids
Browser: contig02:2019855-2023770+
Protein function
EGGNOG: | 0PGUQ | MYO1 | Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2 3 complex |
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SGD closest match: | S000004715 | MYO5 | Myosin-5 |
CGD closest match: | CAL0000199209 | MYO5 | Myosin-5 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_00965_1 | 83.562% | 949 | 0.0 | MCA_00965_1 |
A0A0J9XDY1_GEOCN | 80.084% | 949 | 0.0 | Similar to Saccharomyces cerevisiae YMR109W MYO5 One of two type I myosins OS=Geotrichum candidum GN=BN980_GECA11s01836g PE=3 SV=1 |
A0A060TBS7_BLAAD | 72.679% | 948 | 0.0 | ARAD1D37268p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37268g PE=3 SV=1 |
A0A1E3PEV4_9ASCO | 70.032% | 951 | 0.0 | Myosin-1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84010 PE=3 SV=1 |
MYO1_YARLI | 70.662% | 951 | 0.0 | Myosin-1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MYO1 PE=3 SV=1 |
A0A1E4TL20_9ASCO | 69.118% | 952 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56105 PE=3 SV=1 |
MYO5_YEAST | 66.947% | 950 | 0.0 | Myosin-5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MYO5 PE=1 SV=1 |
UniRef50_P36006 | 66.175% | 949 | 0.0 | Myosin-3 n=39 Tax=Dikarya TaxID=451864 RepID=MYO3_YEAST |
MYO5_CANAL | 66.008% | 962 | 0.0 | Myosin-5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MYO5 PE=1 SV=2 |
A0A167EFC6_9ASCO | 70.960% | 854 | 0.0 | Myosin 5 OS=Sugiyamaella lignohabitans GN=MYO5 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9230
Predicted cleavage: 22
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1286
Detailed signature matches
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SSF52540 (P-loop co...)
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no IPR
Unintegrated signatures
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-
-
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cd01378 (MYSc_Myo1)
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mobidb-lite (disord...)
Residue annotation
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purine-binding loo...
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ATP binding site c...
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P-loop cd01378
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switch I region cd...
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switch II region c...
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relay loop cd01378
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SH1 helix cd01378
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converter subdomai...
Protein sequence
>MIA_01901_1 MAKTQRAGRKDAKRAPPPKRAAASGGIQKAAFDITKKKEVGVSDLTLLSKVSDEAINDNLQKRFENGIIYTYIGHVLISV NPFRDLGIYTDAVLESYRGKNRLEVPPHVFAVAEAMYYNMKSYSESQCVIISGESGAGKTEAAKRIMQYIASVSGQSSTN IQKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLQIQFNRQAEPIGASITNYLLEKARVVGQIQNERNFHIFYQLTKG ATDSQRQTLGIQTPEAYAYTSASKCVSVQGIDDIKDFKETIRAMEIIGLHQTEQDQIFRMLSAILWIGNIDFAENEEGNA KIRDESVPNFVAYLLEVNAADIEKALTERIIETFRGTGRRGSVYESPLNLVQARAVRDALAKAIYNNLFDWIVDRLNQSL EAKEGLDKTIGILDIYGFEIFENNSFEQLCINYVNEKLQQIFIQLTLKTEQDEYVREQIKWTPIDYFNNKIVCDLIEEKR PPGIFSALNDSCATAHADSNAADQNFAQRLSMLTSNPHFETRQTKFLIKHYAGDVYYDIKGMTDKNKDQLLKDLLILVSK TANPFLHSIFPNHVDTESKRRPPTAGDKIKSSANALTSTLSQSQPSYIRTIKPNQTKNPSDYDTKMVLHQIKYLGLHENV RIRRAGFAYRQTYEKFTERFYLLSGKTSYAGDYIWKGDARTATTEILRDAGVPAGEFQMGTTKVFIKTPETLFSLEHMRD MYWHNMAARIQRAWRKYQQKKINAAIKIQRAWRKEKDGDIYLVLRDKGHKILNNRKERRRLSLNGYRRFMGDYLYCNSPK SSGGFTARAVGLNENAIFSMTGETLVHKFGRSSMRVPRTFILTKTKLLIIANQVVNHQLTVVVERNIPVPSIKYLAMSSL RDDWLVISVQSPSEPDPFISCLFKTELVTHLKQLRPNLDLRIGPTVQYFKKPGKVATVKFQTDSTAGRTDLYKSGVVHVA PGCPPNSVSDPTPRKNPRVAGAQAARRPPPARTAAPVAKRNPPPAAPLPTSNARRNPPPPPPATRQQKSPSLHMPASPFQ KQPVRMPEPFGHNNKNAAVAAASAAYNPSVAASAASSPSSPTPTATKRMSSVNRKPVAPTSRPTHHATPQPKPAPAPVAA TPVAAPAPPPPPPPPAAPPAAPTDPLYKALYDFPSSAANQLSVSKDEVLIMKQKGSEGWCLVQRRDGSAEGWAPLSYLEE LRQALPSLSSNGTSTPASGYSQASAASTLASAPQQQQQQQPQLAMGLADALKQKTQQSNQLAGGLAEALKARSGRQDSDD EDDDDW
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003774 motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex