Protein
MIA_01869_1
Length
456 amino acids
Browser: contig02:1926419-1927790-
Protein function
| EGGNOG: | 0PIJD | FG03993.1 | homocitrate synthase |
|---|---|---|---|
| SGD closest match: | S000002289 | LYS21 | Homocitrate synthase, mitochondrial |
| CGD closest match: | CAL0000201759 | LYS22 | Lys22p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01294_1 | 93.674% | 411 | 0.0 | MCA_01294_1 |
| A0A060T9Z1_BLAAD | 90.476% | 420 | 0.0 | ARAD1D18854p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D18854g PE=3 SV=1 |
| A0A167CWA7_9ASCO | 89.362% | 423 | 0.0 | Homocitrate synthase LYS21 OS=Sugiyamaella lignohabitans GN=LYS21 PE=3 SV=1 |
| A0A0J9XBB5_GEOCN | 90.511% | 411 | 0.0 | Similar to Saccharomyces cerevisiae YDL131W LYS21 Homocitrate synthase isozyme OS=Geotrichum candidum GN=BN980_GECA08s01176g PE=3 SV=1 |
| HOSM_YARLI | 89.663% | 416 | 0.0 | Homocitrate synthase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=LYS1 PE=3 SV=1 |
| A0A1E3PL79_9ASCO | 85.450% | 433 | 0.0 | Homocitrate synthase mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82951 PE=3 SV=1 |
| Q59TC4_CANAL | 88.780% | 410 | 0.0 | Lys22p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LYS22 PE=3 SV=1 |
| UniRef50_G3ALA2 | 88.537% | 410 | 0.0 | Homocitrate synthase n=33 Tax=Dikarya TaxID=451864 RepID=G3ALA2_SPAPN |
| A0A1E4TA63_9ASCO | 87.805% | 410 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_127326 PE=3 SV=1 |
| HOSM_YEAST | 88.413% | 397 | 0.0 | Homocitrate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYS21 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0060
Protein family membership
- Homocitrate synthase, fungi/archaea (IPR011872)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
456
Detailed signature matches
no IPR
Unintegrated signatures
-
SSF51569 (Aldolase)
-
cd07948 (DRE_TIM_HCS)
-
mobidb-lite (disord...)
Residue annotation
-
catalytic residues...
-
active site cd07948
-
metal binding site...
Protein sequence
>MIA_01869_1 MTEPTTTKPEAPAASTNGTESLLPKSNPYGPNPSDFLSNVSSFKLIESTLREGEQFANAFFDTEKKIEIAKALDDFGVDY IELTSPAASEQSRKDCEAICKLGLKAKILTHIRCHMDDARLAVATGVDGVDVVIGTSQFLRQFSHGKDMSYIAQSAIEVI EFVKSHNIEIRFSSEDSFRSDLVDLLNIYRTVDKIGVNRVGIADTVGCANPRQVYDLVRTLRSIVSCEIECHFHNDTGCA IANAYSALEAGATLIDVSVLGIGERNGITPLGGLMARMIAADRDYVLSKYKLHKLRDLENLVAEAVHVNIPFNNPITGFC AFTHKAGIHAKAILANPSTYEILNPSDFGLSRYIHFANRLTGWNAIKSRVDQLNLHLTDDQCKEVTAKIKKLGDIRPLNI DDVDSIIRDFHAEVNTPRLGPVGDEPAPKRAKTEASSLSNEVTQVEETKAEEAPSA
GO term prediction
Biological Process
GO:0019752 carboxylic acid metabolic process
GO:0019878 lysine biosynthetic process via aminoadipic acid
Molecular Function
GO:0003824 catalytic activity
GO:0004410 homocitrate synthase activity
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Cellular Component
None predicted.