MIA_01865_1

Protein

Length

551 amino acids

Browser: contig02:1910953-1912609-

Protein function

EGGNOG:	0PJKR	PGUG_05418	transporter
SGD closest match:	S000005069	ESBP6	Uncharacterized transporter ESBP6
CGD closest match:	CAL0000197279	orf19.4337	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_01296_1	62.385%	436	0.0	MCA_01296_1
UniRef50_A2RAW8	33.544%	474	6.47e-85	Aspergillus niger contig An18c0160, genomic contig n=15 Tax=leotiomyceta TaxID=716546 RepID=A2RAW8_ASPNC
A0A1E3PRR6_9ASCO	36.318%	402	4.48e-82	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48771 PE=4 SV=1
A0A1D8PNK9_CANAL	35.766%	411	2.78e-73	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4337 PE=4 SV=1
Q6C0D7_YARLI	34.466%	412	6.02e-73	YALI0F25619p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F25619g PE=4 SV=1
A0A0J9XJQ7_GEOCN	35.071%	422	4.60e-69	Similar to Saccharomyces cerevisiae YNL125C ESBP6 Protein with similarity to monocarboxylate permeases OS=Geotrichum candidum GN=BN980_GECA20s00164g PE=4 SV=1
ESBP6_YEAST	29.111%	450	1.30e-63	Uncharacterized transporter ESBP6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ESBP6 PE=1 SV=1
A0A1E4TCK1_9ASCO	27.603%	413	1.22e-55	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32724 PE=4 SV=1
A0A060TFW4_BLAAD	26.733%	404	3.11e-35	ARAD1D17842p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17842g PE=4 SV=1
A0A167FRE1_9ASCO	28.250%	400	4.11e-28	Mch5p OS=Sugiyamaella lignohabitans GN=MCH5 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0263

Protein family membership

None predicted.

Domains and repeats

Domain
105 - 502
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 551

Detailed signature matches

IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  105 - 502
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  122 - 501
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

183 - 188

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

380 - 390

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

245 - 250

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

302 - 325

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

443 - 453

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

501 - 551

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 119

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

318 - 517

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

100 - 312

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

212 - 222

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

410 - 414

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

271 - 281

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

144 - 162

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

349 - 359

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

474 - 478

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

252 - 274

TMHMM
TMhelix (TMhelix)

326 - 348

TMHMM
TMhelix (TMhelix)

160 - 182

TMHMM
TMhelix (TMhelix)

413 - 435

TMHMM
TMhelix (TMhelix)

123 - 145

TMHMM
TMhelix (TMhelix)

189 - 208

TMHMM
TMhelix (TMhelix)

479 - 501

TMHMM
TMhelix (TMhelix)

386 - 408

TMHMM
TMhelix (TMhelix)

450 - 472

TMHMM
TMhelix (TMhelix)

279 - 301

TMHMM
TMhelix (TMhelix)

223 - 245

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

479 - 500

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

251 - 270

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

415 - 442

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

454 - 473

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

189 - 211

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

360 - 379

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

326 - 348

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

282 - 301

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

120 - 143

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

223 - 244

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

391 - 409

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

163 - 182

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

92 - 112

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 27

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

136W

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

139S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

140G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

141A

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

143G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

144V

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

167G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

170Q

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

171F

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

174G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

178S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

179P

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

181V

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

182V

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

229I

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

230G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

233F

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

234V

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

237N

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

238A

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

241P

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

252Y

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

253G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

256T

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

257C

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

263S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

336T

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

339C

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

340Y

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

343V

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

344L

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

347M

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

361G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

365S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

369S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

372I

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

376R

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

424G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

427V

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

428S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

431S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

435P

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

436P

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

439A

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

450M

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

451M

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

454S

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

455W

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

458I

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

459G

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

462N

putative substrate translocation pore
136W, 139S, 140G, 141A, 143G, 144V, 167G, 170Q, 171F, 174G, 178S, 179P, 181V, 182V, 229I, 230G, 233F, 234V, 237N, 238A, 241P, 252Y, 253G, 256T, 257C, 263S, 336T, 339C, 340Y, 343V, 344L, 347M, 361G, 365S, 369S, 372I, 376R, 424G, 427V, 428S, 431S, 435P, 436P, 439A, 450M, 451M, 454S, 455W, 458I, 459G, 462N
CDD
cd06174 (MFS)

Protein sequence

>MIA_01865_1
MSSPLKEKSIEVTINVPQPTSSQEKEGHMSDTFYCGETGSNLNLSVTATHRHHHLHNTISNVDYGAAETMLMEGQDLSGH
ISPTASNIRCSREDTEAGGATVANSTEEDEEPELEFDHGYAWVVLIAGTLINAFSWGASGAFGVFLATFLDTNKYPGATR
MDFAFVGGLQFGLGLMVSPFVVQAIQKVSFTVFIIAGSFVLAGGNIAASFATRIWHLYLTQGLLSGVGIGMVFVTANAAV
PMWFVQRRGVAYGIFTCGAGLGSIIFSLSVQSLIDRVGLAWAQRYVGFMTFGFCVFSGIFIKERRSVYKSRGANAYNFAL
LKRPDLLLAIFWGIITMLCYGIVLYTMAPYAVSVGLTHHQGSVLSSVVSAGIVVGRPVMGYCADKIGSLNIALVTTVLST
IFILAWWIPSKSYGSLIALSFCLGSVVSSFSAGFPPICASLVDLEDLSAMMSMSWTVIGALNVFSTPVAIGLTTVNDTYL
YSQIFTGLLFFVSSVILIVIRGIEFRIQERENQMAEKSICTSTSCTDEGCNEIKEVKQASFISLMFKIAKV

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

MIA_01865_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component