Protein
MIA_01849_1
Length
855 amino acids
Browser: contig02:1866928-1869496+
Protein function
EGGNOG: | 0PHG7 | AFG3 | Mitochondrial inner membrane AAA protease Yta12 |
---|---|---|---|
SGD closest match: | S000004695 | YTA12 | Mitochondrial respiratory chain complexes assembly protein YTA12 |
CGD closest match: | CAL0000178083 | orf19.2057 | M-AAA protease subunit |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MCA_02360_1 | 85.978% | 649 | 0.0 | MCA_02360_1 |
A0A0J9XFM5_GEOCN | 81.126% | 657 | 0.0 | Similar to Saccharomyces cerevisiae YER017C AFG3 Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease OS=Geotrichum candidum GN=BN980_GECA14s00736g PE=3 SV=1 |
A0A167CIR1_9ASCO | 69.159% | 642 | 0.0 | M-AAA protease subunit YTA12 OS=Sugiyamaella lignohabitans GN=YTA12 PE=3 SV=1 |
A0A1E4TLX6_9ASCO | 71.215% | 601 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30822 PE=3 SV=1 |
A0A060T0T5_BLAAD | 68.305% | 590 | 0.0 | ARAD1C17974p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C17974g PE=3 SV=1 |
UniRef50_A0A0J9X4K4 | 67.912% | 589 | 0.0 | Similar to Saccharomyces cerevisiae YER017C AFG3 Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease n=2 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9X4K4_GEOCN |
A0A1E3PEY3_9ASCO | 66.611% | 599 | 0.0 | ATP-dependent metallopeptidase Hfl OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_27809 PE=3 SV=1 |
YTA12_YEAST | 64.883% | 598 | 0.0 | Mitochondrial respiratory chain complexes assembly protein YTA12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YTA12 PE=1 SV=2 |
Q6CHB1_YARLI | 61.622% | 641 | 0.0 | YALI0A10615p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A10615g PE=3 SV=1 |
Q5AD10_CANAL | 63.921% | 607 | 0.0 | M-AAA protease subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2057 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9976
Predicted cleavage: 68
Protein family membership
- Peptidase, FtsH (IPR005936)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
600
700
800
855
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
-
-
NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SSF140990 (FtsH pro...)
-
-
TRANSMEMBRANE (Tran...)
-
cd00009 (AAA)
-
mobidb-lite (disord...)
Residue annotation
-
Walker A motif cd0...
-
ATP binding site c...
-
Walker B motif cd0...
-
arginine finger cd...
Protein sequence
>MIA_01849_1 MATTAVMLGRAIAAAPRTCASPASSSTYAIRGARSTLLALQRPVSLRTTNSNILLFRSFSASAACREAPNDNNNNNSNNN SSESEDDLTSRKRRLARMRRRLSANKNGLPNISDSTRDRLDRAKWTNVSGNSESKNNDEQLKNSEDEKSADNIGKQPEWY RAEKPAEDTQKSSSSSKSDESSKKDDNDADKNNDSDKTSKQKNGKPMPPGFDFNSQNFRVFEIKITPMHILIFFILTSFF FTLMSQGGMSNSEISWQDFKTEYLDKGSVRKLTVVNKSTVYVTTTFGSTVFFTIGSVDTFEKRMDEAQVGVPANERIPIS YIEQGSFLGALFGFLPTLLLLGALFWMTRRPSGGSGGGLGGGIFGMGQSRAKLYNKATDVNVKFADVAGMEEAKEEIMEF VKFLKEPAKYEELGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFFSVSGSEFIEMFAGVGASRVRDLFKAARAKAPSI IFIDEIDAIGKARNKSFVSGGHDEREATLNQLLVEMDGFESSDHVVVLAGTNRADVLDPALLRPGRFDRHITIDRPDIEG RISIYKVHLKKILYNKDIPELPGKLAAMTPGFSGADIANVVNEAALIAARQEAPLVELKHFEQAIERVIAGLEKKSRVLV PEKKKIVAYHEAGHAICGWYLKYADPLVKVSIIPRGSAALGYAQYLPPDQYLISEEQFKDKMAMSLGGRVSEEINFPSVT LGGSDDFKKVTQMAKAMVTQLGMSDKVGQVYYEQNQESITKPYSEHTGELIDSEIRRIVREAHERCHKLLTEKKKEVEIV AEELLKKEVISREDMIRLLGPRPFPERNDAFDKYLSQTPQKHDDNGASSAPAASA
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane