MCA_02360_1
Gene name: YTA12
Description: Mitochondrial respiratory chain complexes assembly protein YTA12; Mitochondrial inner membrane m-AAA protease component
Browser: contigB:1053531-1056048+
RNA-seq: read pairs 16911, FPKM 249.1, percentile rank 90.4% (100% = highest expression)
Protein function
| Annotation: | YTA12 | Mitochondrial respiratory chain complexes assembly protein YTA12; Mitochondrial inner membrane m-AAA protease component | |
|---|---|---|---|
| KEGG: | K08956 | AFG3 | AFG3 family protein [EC:3.4.24.-] |
| EGGNOG: | 0PHG7 | AFG3 | Mitochondrial inner membrane AAA protease Yta12 |
| SGD closest match: | S000004695 | YTA12 | Mitochondrial respiratory chain complexes assembly protein YTA12 |
| CGD closest match: | CAL0000178083 | orf19.2057 | M-AAA protease subunit |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01849_1 | 81.75% | 696 | 0.0 | MIA_01849_1 |
| A0A0J9XFM5_GEOCN | 81.54% | 661 | 0.0 | Similar to Saccharomyces cerevisiae YER017C AFG3 Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease OS=Geotrichum candidum GN=BN980_GECA14s00736g PE=3 SV=1 |
| A0A167CIR1_9ASCO | 68.12% | 643 | 0.0 | M-AAA protease subunit YTA12 OS=Sugiyamaella lignohabitans GN=YTA12 PE=3 SV=1 |
| A0A1E4TLX6_9ASCO | 68.56% | 633 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30822 PE=3 SV=1 |
| A0A1E3PCQ3_9ASCO | 64.64% | 642 | 0.0 | ATP-dependent metallopeptidase Hfl OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84386 PE=3 SV=1 |
| A0A060T0T5_BLAAD | 61.20% | 665 | 0.0 | ARAD1C17974p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C17974g PE=3 SV=1 |
| Q6CHB1_YARLI | 63.14% | 643 | 0.0 | YALI0A10615p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A10615g PE=3 SV=1 |
| YTA12_YEAST | 65.22% | 598 | 0.0 | Mitochondrial respiratory chain complexes assembly protein YTA12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YTA12 PE=1 SV=2 |
| Q5AD10_CANAL | 60.95% | 671 | 0.0 | M-AAA protease subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2057 PE=3 SV=1 |
| UniRef50_A0A0J9X4K4 | 64.33% | 614 | 0.0 | Similar to Saccharomyces cerevisiae YER017C AFG3 Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease n=2 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9X4K4_GEOCN |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7862
Predicted cleavage: 60
Protein family membership
- Peptidase, FtsH (IPR005936)
Domains and repeats
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Domain
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Domain
Detailed signature matches
no IPR
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CYTOPLASMIC_D... (C...)
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-
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NON_CYTOPLASM... (N...)
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SSF140990 (FtsH pro...)
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TRANSMEMBRANE (Tran...)
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cd00009 (AAA)
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mobidb-lite (disord...)
Residue annotation
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Walker A motif cd0...
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ATP binding site c...
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Walker B motif cd0...
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arginine finger cd...
Protein sequence
>MCA_02360_1 MTAVLPGRTAMATRTVGMNGRASALLSSQLVKSPANIRLISSFNKQVAILSKPVTTQRHESNPLLNLSYSITSYSSISRI SDSKRTFSTFRALQDEHNTGEDLRKKRLARLRKRMLQASSKSDVNKRAPREEEVHSSNKENKIFDEDDADVQQPKWYQER QSSSDTNQNKSRSDENKENEEDTQKKNKGQPMPPGFDFNSKNFRVFEIKITPQHILIGLLVTFIFMSLASQGSMNTNEIS WQEFQREYLDKGAVRKLTVVNKSTVYVNTGFGSSVYFTIGSIDLFEKRMEEAQKGVPPNERIPINYIEQGSLLSTLFSFL PTLLLLGAMFWMTRKPSGGQGGFGGGLFGMGQSKAKLYNKATDVNVKFADVAGMDEAKEEIMEFVKFLKEPAKYEELGAK IPRGAILSGPPGTGKTLLAKATAGEANVPFFTVSGSEFIEMFAGVGASRVRDLFKAARAKAPSIIFIDEIDAIGKARNKG FVSGGHDEREATLNQLLVEMDGFESSDHVVVLAGTNRADVLDAALLRPGRFDRHITIDRPDIEGRISIYNVHLKKIKYNK DIPQLSGKLAAMTPGFSGADIANVVNEAALIAARQESDVVELVHFEQAIERVIAGLEKKTKVLVPEKKKIVAYHEAGHAV CGWFLKFADPLVKVSIIPRGSAALGYAQYLPPDQYLISEEQFKDKMAMSLGGRVSEELNFPSVTLGGSDDFNKVTQMAKA MVTQLGMSPKVGQVFYEQNQESIAKPYSENTGEIIDSEIRRIVNEAHERCRELLIEKQAEVKLVAEELLTKEVITREDMI RLLGPRPFPERNDAFDKYLSDTPDKKSPTEDSSSPSPA
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane