Protein
MIA_01799_1
Length
136 amino acids
Browser: contig02:1704324-1704735-
Protein function
EGGNOG: | 0PNT7 | HTB1 | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling |
---|---|---|---|
SGD closest match: | S000002632 | HTB1 | Histone H2B.1 |
CGD closest match: | CAL0000196000 | HTB1 | Histone H2B.1 |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
A0A0J9XAL7_GEOCN | 95.146% | 103 | 1.15e-69 | Histone H2B OS=Geotrichum candidum GN=BN980_GECA07s01176g PE=3 SV=1 |
A0A167D9K5_9ASCO | 95.146% | 103 | 5.58e-70 | Histone H2B OS=Sugiyamaella lignohabitans GN=HTB1 PE=3 SV=1 |
MCA_02823_1 | 95.146% | 103 | 1.69e-69 | MCA_02823_1 |
A0A060T075_BLAAD | 95.146% | 103 | 1.38e-69 | Histone H2B OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C14366g PE=3 SV=1 |
A0A1E4TCP2_9ASCO | 89.320% | 103 | 1.22e-66 | Histone H2B OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4158 PE=3 SV=1 |
A0A1E3PP03_9ASCO | 89.320% | 103 | 1.86e-64 | Histone H2B OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40149 PE=3 SV=1 |
H2B1_CANAL | 90.816% | 98 | 5.53e-64 | Histone H2B.1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HTB1 PE=3 SV=3 |
H2B1_YEAST | 87.255% | 102 | 1.00e-63 | Histone H2B.1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HTB1 PE=1 SV=2 |
UniRef50_P02293 | 87.255% | 102 | 2.40e-60 | Histone H2B.1 n=213 Tax=cellular organisms TaxID=131567 RepID=H2B1_YEAST |
H2B_YARLI | 86.275% | 102 | 3.43e-62 | Histone H2B OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HTB1 PE=3 SV=3 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3253
Protein family membership
- Histone H2B (IPR000558)
Domains and repeats
-
Domain
1
20
40
60
80
100
120
136
Detailed signature matches
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Protein sequence
>MIA_01799_1 MAPPKTAGKAPASKAPAKAPAEKKEAGKKTTSSVSGDKKKRTKARKQTYSSYIYKVLKQTHPDTGISTRAMSIMNSFVND IFERVATEASKLAAYNKRSTISSREIQTAVRLILPGELAKHAISEGTRAVTKYTSS
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003677 DNA binding
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome