Protein

MIA_01799_1

Length
136 amino acids


Browser: contig02:1704324-1704735-

Protein function

EGGNOG:0PNT7HTB1Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
SGD closest match:S000002632HTB1Histone H2B.1
CGD closest match:CAL0000196000HTB1Histone H2B.1

Protein alignments

%idAln lengthE-value
A0A0J9XAL7_GEOCN95.146%1031.15e-69Histone H2B OS=Geotrichum candidum GN=BN980_GECA07s01176g PE=3 SV=1
A0A167D9K5_9ASCO95.146%1035.58e-70Histone H2B OS=Sugiyamaella lignohabitans GN=HTB1 PE=3 SV=1
MCA_02823_195.146%1031.69e-69MCA_02823_1
A0A060T075_BLAAD95.146%1031.38e-69Histone H2B OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C14366g PE=3 SV=1
A0A1E4TCP2_9ASCO89.320%1031.22e-66Histone H2B OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4158 PE=3 SV=1
A0A1E3PP03_9ASCO89.320%1031.86e-64Histone H2B OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40149 PE=3 SV=1
H2B1_CANAL90.816%985.53e-64Histone H2B.1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HTB1 PE=3 SV=3
H2B1_YEAST87.255%1021.00e-63Histone H2B.1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HTB1 PE=1 SV=2
UniRef50_P0229387.255%1022.40e-60Histone H2B.1 n=213 Tax=cellular organisms TaxID=131567 RepID=H2B1_YEAST
H2B_YARLI86.275%1023.43e-62Histone H2B OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HTB1 PE=3 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3253

Protein family membership

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 136

Detailed signature matches

    1. SM00427 (h2b3)
    2. PS00357 (HISTONE_H2B)
    3. PR00621 (HISTONEH2B)
    1. SSF47113 (Histone-fold)
    1. PF00125 (Histone)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_01799_1
MAPPKTAGKAPASKAPAKAPAEKKEAGKKTTSSVSGDKKKRTKARKQTYSSYIYKVLKQTHPDTGISTRAMSIMNSFVND
IFERVATEASKLAAYNKRSTISSREIQTAVRLILPGELAKHAISEGTRAVTKYTSS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003677 DNA binding
GO:0046982 protein heterodimerization activity

Cellular Component

GO:0000786 nucleosome