Protein

MIA_01785_1

Length
695 amino acids

Browser: contig02:1678675-1680763-

Protein function

EGGNOG:0PG9QPGUG_03791multidrug resistance transporter
SGD closest match:S000000247QDR3Quinidine resistance protein 3
CGD closest match:CAL0000174097QDR3MFS antiporter QDR3

Protein alignments

%idAln lengthE-value
MCA_02812_152.816%6570.0MCA_02812_1
A0A060T3G1_BLAAD44.608%6120.0ARAD1C33044p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33044g PE=4 SV=1
UniRef50_A0A060T3G144.608%6120.0ARAD1C33044p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T3G1_BLAAD
A0A167DUI6_9ASCO39.598%6972.04e-167Qdr3p OS=Sugiyamaella lignohabitans GN=QDR3 PE=4 SV=1
Q6C335_YARLI37.576%6601.61e-159YALI0F02959p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02959g PE=4 SV=1
A0A1E3PDF4_9ASCO38.769%6506.90e-153MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53589 PE=4 SV=1
QDR3_CANAL40.717%6143.53e-154MFS antiporter QDR3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=QDR3 PE=2 SV=2
QDR3_YEAST36.443%6862.32e-150Quinidine resistance protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QDR3 PE=1 SV=2
A0A1E4TC15_9ASCO37.559%6393.13e-145Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29229 PE=4 SV=1
A0A0J9X8U3_GEOCN45.936%2835.71e-86Similar to Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter of the major facilitator superfamily OS=Geotrichum candidum GN=BN980_GECA05s04949g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0248

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 695

Detailed signature matches

  1. Family IPR011701
    Major facilitator superfamily
    1. PF07690 (MFS_1)
  2. Domain IPR020846
    Major facilitator superfamily domain
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.12...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Residue annotation

  1. putative substrate...
  2. putative substrate...

Protein sequence

>MIA_01785_1
MDEDITTYKNQARLSINNLDTRATPNTSSDSCPRISITSDNSFTVQNIYQETPANTETRTDCAPDISTEKSNFQEETKNC
SGIIPRHDRRGLFSNLILIDELSNPIEYGSFKKTFILILIAYAAIVGPMGGSVFLPAIEDICAEMNVGKDVVNISYGIYV
LSLAFFPLWWSSFSEQFGRRNIYIVSFGAYFCFLIGCALVKNIGSLMVLRFLAGGCAASVQAVGAGTLADIYIPTERGSA
MGYFYLGPLLGPMIGPIFGGLIVERWGWRGTQWFLVIISGSIILTIVFFLPETLHRRSRSTSEPVTHTNQLEKKSSHNEN
AVKAQKDKSDSTSFSNNILNNELVSSDVENGLDSSSQRGNTSGNRRMSLSSLASQLPVDDLDNSNVGDTFLPMIPSPSRV
LEMESEGKIHDHQKPRNPDIDTDLEYQVSELEKAQKIKTTASEKERRLINSSGQVDFQSLTFGEKLEWLIIRPLFTFKFL
QYPPVTLTIVYGSICFMVLYFLNVGIETLYSGSPYEFNSIYVGLCYIPNSIGYIISSIVAGRYSDFVVRREKKKLGYFNA
ESRFAEHVLFAMVLYPISIIMFGWTANYKLHWVVPLVGSFLFGLSSMVVLGNSATYLVDALPGKGSSGIALNNFIRFILA
AIATFVAEPMKTGMGFGWMYTFLGLLAVVSSIAVFSIRRWGNKWRNEADFEKMYR

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane