Protein

MCA_02812_1

Length
654 amino acids

Browser: contigB:2441332-2443297-

RNA-seq: read pairs 400, FPKM 7.5, percentile rank 21.5% (100% = highest expression)

Protein function

EGGNOG:0PG9QPGUG_03791multidrug resistance transporter
SGD closest match:S000000247QDR3Quinidine resistance protein 3
CGD closest match:CAL0000174097QDR3MFS antiporter QDR3

Protein alignments

%idAln lengthE-value
MIA_01785_154.71%6160.0MIA_01785_1
A0A060T3G1_BLAAD43.59%5851e-137ARAD1C33044p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33044g PE=4 SV=1
UniRef50_A0A060T3G143.59%5853e-134ARAD1C33044p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T3G1_BLAAD
A0A0J9X8U3_GEOCN44.10%5854e-137Similar to Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter of the major facilitator superfamily OS=Geotrichum candidum GN=BN980_GECA05s04949g PE=4 SV=1
Q6C335_YARLI38.06%5997e-121YALI0F02959p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02959g PE=4 SV=1
A0A167DUI6_9ASCO40.17%5803e-120Qdr3p OS=Sugiyamaella lignohabitans GN=QDR3 PE=4 SV=1
A0A1E3PDF4_9ASCO38.78%5889e-106MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53589 PE=4 SV=1
QDR3_YEAST36.76%6235e-104Quinidine resistance protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QDR3 PE=1 SV=2
QDR3_CANAL37.77%5936e-103MFS antiporter QDR3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=QDR3 PE=2 SV=2
A0A1E4TC15_9ASCO37.26%5858e-100Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29229 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0233
Predicted cleavage: 49

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 654

Detailed signature matches

  1. Family IPR011701
    Major facilitator superfamily
    1. PF07690 (MFS_1)
  2. Domain IPR020846
    Major facilitator superfamily domain
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.12...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Residue annotation

  1. putative substrate...
  2. putative substrate...

Protein sequence

>MCA_02812_1
MNIPQTPTSAECTSSNSANSSTSNQHSENTPHNTPPIKRSISQSHQPQQNSETQQTPTEEKEKKSQQEVKATEYCPRNER
RGILTFFLISNEAVHPYQYPKRTKSVILLVNALAGAIGPMGGAVFLPAMEEICEQFNTTKDIVNISYGTYVLSLAFFPLW
WSSLSEQFGRRSIFIISFICYIGFVIACALSQSIAMLMVFRFFSGACAAAIQALGAGTMSDIYVPTERGTAMGYFYLGPL
LGPLVGPIFGGLLVDRFTWRGTMWFLVIISGVITVAMIVLVPETLHGRLPNNNNKNNSDSNKNEKTIVQDEEEEEDTKSA
QKNLTTEKTNSSESVSNEPTLLVSATRNDTILIDNNRNEPEFPIATLTYTGEPLPSTERDIYIEQELGGAAELSKVKTTA
SEKEQRLIKFSGPVDFTTLTYSQKAYHLIIRPFYSFKFLAYPPVTLAIINGAICFMNLYFFNVGLETLYTSSPYNFSPIL
VGLTYIPNSVGYVISSIAAGKYSDHVVRKVKAKHGSFPAESRFAIHVYIAMVGYTISIFFFGWTAYYQLHWVIPLIGSFL
FGLTSMVLLASTATYLVDALPGKGSSGIALNNFIRFLLAAVSTFVAEPWKEGMGFGWMYTILGFIAALSSITIIMIRKWG
NKWRSQADFEKMYA

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane