Protein

MIA_01749_1

Length
397 amino acids


Browser: contig02:1575699-1576893+

Protein function

EGGNOG:0PGPCTAF4Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre- initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by taf1), facilitation of DNA opening and initiation of transcription (By similarity)
SGD closest match:S000004607TAF4Transcription initiation factor TFIID subunit 4
CGD closest match:CAL0000193600TAF4Transcription initiation factor TFIID subunit 4

Protein alignments

%idAln lengthE-value
MCA_02835_145.093%4281.95e-74MCA_02835_1
A0A161HMI7_9ASCO34.682%3466.34e-30Taf4p OS=Sugiyamaella lignohabitans GN=TAF4 PE=4 SV=1
UniRef50_A0A161HMI734.682%3461.74e-26Taf4p n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HMI7_9ASCO
A0A1E3PSW2_9ASCO35.279%3943.13e-25TAF4-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81112 PE=4 SV=1
A0A0J9XK27_GEOCN35.926%2701.20e-23Similar to Saccharomyces cerevisiae YMR005W TAF4 TFIID subunit (48 kDa) OS=Geotrichum candidum GN=BN980_GECA25s00065g PE=4 SV=1
Q6C2N6_YARLI35.802%2431.35e-18YALI0F06372p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F06372g PE=4 SV=2
A0A060T0M6_BLAAD36.982%3384.97e-16ARAD1C09460p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09460g PE=4 SV=1
TAF4_YEAST27.451%2556.56e-11Transcription initiation factor TFIID subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAF4 PE=1 SV=1
TAF4_CANAL24.151%2658.80e-09Transcription initiation factor TFIID subunit 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TAF4 PE=3 SV=2
A0A1E4TK48_9ASCO28.230%2093.58e-08Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17165 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1152
Predicted cleavage: 29

Protein family membership

None predicted.

Domains and repeats

1 50 100 150 200 250 300 350 397

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_01749_1
MSDNQAISAYSSKRTSPAPASQPVAKRVKVLNDSSTPSVINSSHGPIVPMTSNTASSSSLDPEMLSDALLSAGVDIKEEE
SLLSRSLYGSGSNSGSKYSTNLAPGVGSGSISLNESGNNGHVSKESYGVGAPALPPLLERIYEYQQRRNQTPFLDPGRLQ
YIFNSHAHDMGLALSKDMREVDAMLTLISYSCQEWISDIVTSSLVISRHRRRSRNNVHSEVSRALRNIAQKEKEDEEKRL
VRKAQKLGENEENGEGKGVSGTGNGSGLSKKERSNADDSNTNEEGSKVRGRGRGAQSDEINYSAANATVQMMTLGSKRKY
SWLTEGTNTGGAGNATNAPNSVLNIRGSGAGLRSDGTVRYREVREEQGLVVRDLMLALEHQRAGVLNAIMKGYSKKS

GO term prediction

Biological Process

GO:0006352 DNA-templated transcription, initiation

Molecular Function

None predicted.

Cellular Component

GO:0005669 transcription factor TFIID complex