Protein
MCA_02835_1
Length
401 amino acids
Gene name: TAF4
Description: Transcription initiation factor TFIID subunit 4
Browser: contigB:2481874-2483080-
RNA-seq: read pairs 1026, FPKM 31.5, percentile rank 54.1% (100% = highest expression)
Protein function
| Annotation: | TAF4 | Transcription initiation factor TFIID subunit 4 | |
|---|---|---|---|
| EGGNOG: | 0PGPC | TAF4 | Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre- initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by taf1), facilitation of DNA opening and initiation of transcription (By similarity) |
| SGD closest match: | S000004607 | TAF4 | Transcription initiation factor TFIID subunit 4 |
| CGD closest match: | CAL0000193600 | TAF4 | Transcription initiation factor TFIID subunit 4 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01749_1 | 50.70% | 359 | 8e-84 | MIA_01749_1 |
| UniRef50_A0A061AUC6 | 34.04% | 235 | 3e-28 | CYFA0S06e04698g1_1 n=1 Tax=Cyberlindnera fabianii TaxID=36022 RepID=A0A061AUC6_CYBFA |
| A0A0J9XK27_GEOCN | 37.08% | 267 | 9e-30 | Similar to Saccharomyces cerevisiae YMR005W TAF4 TFIID subunit (48 kDa) OS=Geotrichum candidum GN=BN980_GECA25s00065g PE=4 SV=1 |
| A0A1E3PSW2_9ASCO | 36.60% | 235 | 4e-28 | TAF4-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81112 PE=4 SV=1 |
| A0A060T0M6_BLAAD | 37.71% | 236 | 7e-28 | ARAD1C09460p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09460g PE=4 SV=1 |
| A0A161HMI7_9ASCO | 35.90% | 234 | 2e-25 | Taf4p OS=Sugiyamaella lignohabitans GN=TAF4 PE=4 SV=1 |
| Q6C2N6_YARLI | 35.19% | 233 | 6e-24 | YALI0F06372p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F06372g PE=4 SV=2 |
| TAF4_YEAST | 31.97% | 244 | 1e-21 | Transcription initiation factor TFIID subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAF4 PE=1 SV=1 |
| TAF4_CANAL | 28.79% | 257 | 1e-16 | Transcription initiation factor TFIID subunit 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TAF4 PE=3 SV=2 |
| A0A1E4TK48_9ASCO | 30.81% | 198 | 8e-13 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17165 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0311
Predicted cleavage: 30
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
401
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MCA_02835_1 MVDSTQSSRKSSPAPPNPSASYQHATKRFKTGNEVSTPTSSSTTASKPGNAPPNATGSSALDPDTLSDVLLSAGVDLKEE ESFLSRSIYGGSSALNRSATSGTGTSGQGGSHLSNDSSSGQRGSISSSVTVSGPSKTSGSGDVDDGTLPPILERIYKYQE QNRAAPFLDPGRLQLILSNHAKDSGVTLPTDVKELEAMLYLVSYSCKEWVSDILTNALVLSRHRRRARTGVYSDVSRALR KIANQEKTEEDKRAEKKAQLLAQGEENGLNGENKGSGEGKAKGDNASAGDDHKDGSSKRGKNASAVDEINYSVTNATVNM MTLGGSKRKYSWLTEGASGGGNAGGSGGNRGLGTGLRSDGTARFREVREEQTLVVRDLLGALEHQRAGVHKTLLKGYTKR Y
GO term prediction
Biological Process
GO:0006352 DNA-templated transcription, initiation
Molecular Function
None predicted.
Cellular Component
GO:0005669 transcription factor TFIID complex