Protein
MIA_01736_1
Length
361 amino acids
Browser: contig02:1540414-1541500+
Protein function
| EGGNOG: | 0PIMK | DRE2 | Component of the cytosolic iron-sulfur (Fe S) protein assembly machinery. Required for the maturation of extramitochondrial Fe S proteins (By similarity). Has anti- apoptotic effects in the cell. Involved in negative control of H(2)O(2)-induced cell death, probably by tethering the pro- apoptotic factor tah18 in the cytoplasm in the absence of oxidative stress (By similarity) |
|---|---|---|---|
| SGD closest match: | S000001779 | DRE2 | Fe-S cluster assembly protein DRE2 |
| CGD closest match: | CAL0000199333 | DRE2 | Fe-S cluster assembly protein DRE2 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01466_1 | 52.910% | 378 | 6.43e-96 | MCA_01466_1 |
| A0A0J9XKJ8_GEOCN | 41.210% | 347 | 4.57e-46 | Fe-S cluster assembly protein DRE2 OS=Geotrichum candidum GN=DRE2 PE=3 SV=1 |
| UniRef50_A0A0J9XKJ8 | 41.210% | 347 | 9.35e-43 | Fe-S cluster assembly protein DRE2 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKJ8_GEOCN |
| A0A060TI70_BLAAD | 34.706% | 340 | 2.86e-39 | Fe-S cluster assembly protein DRE2 OS=Blastobotrys adeninivorans GN=DRE2 PE=3 SV=1 |
| A0A167G0E1_9ASCO | 37.069% | 348 | 2.28e-36 | Fe-S cluster assembly protein DRE2 OS=Sugiyamaella lignohabitans GN=DRE2 PE=3 SV=1 |
| DRE2_YARLI | 64.486% | 107 | 1.52e-35 | Fe-S cluster assembly protein DRE2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DRE2 PE=3 SV=1 |
| A0A1E3PPC7_9ASCO | 32.029% | 409 | 1.12e-33 | Fe-S cluster assembly protein DRE2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=DRE2 PE=3 SV=1 |
| A0A1E4TDF5_9ASCO | 59.055% | 127 | 3.63e-30 | Fe-S cluster assembly protein DRE2 OS=Tortispora caseinolytica NRRL Y-17796 GN=DRE2 PE=3 SV=1 |
| DRE2_CANAL | 42.857% | 140 | 8.15e-24 | Fe-S cluster assembly protein DRE2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DRE2 PE=3 SV=1 |
| DRE2_YEAST | 68.627% | 51 | 2.26e-17 | Fe-S cluster assembly protein DRE2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DRE2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0965
Protein family membership
- Anamorsin (IPR007785)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
361
Detailed signature matches
-
-
PF16803 (DRE2_N)
-
no IPR
Unintegrated signatures
Protein sequence
>MIA_01736_1 MPEPTSNILTTPINRILLLLTADAVKSPQFVESITNKFKHNVSTNEIHRHVLDRVLSGAAKLPSCYFSTVYYLPSSSEEQ EELFTTPGALESLFDSIEYNGTLQTLLLSSASSPDIPVITPKMITTAIIAGFLQSDDKLSFKKPHQLVESTAPATLLNRR SKVQSDKTTENTTITTKKKLPIFKRKQTDATTENDSVSLKTTNLPQNSDNLSSGVVKLTLSDDFNDNDDSMDDGLIDENT LLMEAAKNLSKPIVLPAKCDPGPGKRRRKACKDCTCGLRELEIQEEEEQRKKQDAVILNLDGDGGDDDYAIDFTVTVGKP VGSCGSCALGDAFRCDSCPYLGLPPFKPGEIIDITSIKNDL
GO term prediction
Biological Process
GO:0016226 iron-sulfur cluster assembly
Molecular Function
GO:0051536 iron-sulfur cluster binding
Cellular Component
GO:0005737 cytoplasm