Protein
MIA_01727_1
Length
615 amino acids
Browser: contig02:1512506-1514405+
Protein function
| EGGNOG: | 0PFS9 | FCJ1 | Multifunctional regulator of mitochondrial architecture and protein biogenesis. May act in concert with ATP synthase dimers to generate inner membrane structure and consequently normal mitochondrial morphology. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity) |
|---|---|---|---|
| SGD closest match: | S000001724 | MIC60 | MICOS complex subunit MIC60 |
| CGD closest match: | CAL0000200955 | MIC60 | MICOS complex subunit MIC60 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_00572_1 | 54.120% | 619 | 0.0 | MCA_00572_1 |
| A0A0J9X2J5_GEOCN | 45.541% | 527 | 6.35e-131 | MICOS complex subunit MIC60 OS=Geotrichum candidum GN=BN980_GECA01s02540g PE=3 SV=1 |
| UniRef50_A0A0J9X2J5 | 45.541% | 527 | 1.30e-127 | MICOS complex subunit MIC60 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2J5_GEOCN |
| A0A167EZW3_9ASCO | 49.864% | 367 | 8.04e-105 | MICOS complex subunit MIC60 OS=Sugiyamaella lignohabitans GN=MIC60 PE=3 SV=1 |
| A0A1E3PFA7_9ASCO | 36.295% | 529 | 1.80e-104 | MICOS complex subunit MIC60 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53063 PE=3 SV=1 |
| A0A060THT5_BLAAD | 41.321% | 530 | 4.50e-97 | MICOS complex subunit MIC60 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D33990g PE=3 SV=1 |
| MIC60_YARLI | 44.054% | 370 | 5.48e-84 | MICOS complex subunit MIC60 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MIC60 PE=3 SV=1 |
| A0A1E4TBE1_9ASCO | 43.262% | 282 | 2.97e-62 | MICOS complex subunit MIC60 (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20184 PE=3 SV=1 |
| MIC60_CANAL | 32.275% | 378 | 3.55e-41 | MICOS complex subunit MIC60 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MIC60 PE=3 SV=2 |
| MIC60_YEAST | 40.000% | 110 | 3.58e-20 | MICOS complex subunit MIC60 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MIC60 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9902
Predicted cleavage: 37
Protein family membership
- Mitochondrial inner membrane protein Mitofilin (IPR019133)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
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-
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MIA_01727_1 MLGSIATVARSGAVAKQLAAKSFTSTRALSGSAARYVSKPPGAGDLPPMVFEGRPIKEPKQPEKQEKSDSSTPPPPPPPP APQAKPIKKTHRFRNFILYTLGLTTIAYGGAVYYSLDDDAFRDLFTENVPFAEDVIYFLEEQRFKRRFAKDLPTIASLPF SSDSSPSSITSSKTTVTQSRASGASTTLKPPVDGHDVDPAAANILKNANNKQQPKSVSPETPSIATTPKEATSASASSSS STSAIKPSLPLISVPAGADPAVTKSIERLNAFIEVVNQSKASSADVEAISNELHALSISIDAIKATTAAEAKKLAANNIA KSEHRLESSINELKTAVSAQEEKWAREFHDETKRLAQAYNERLQNEVNAANRVIFAHANNQLLAVHAAREREFAKHVVER VEAEREGRLSNLKELADEVSNVQELVVKTDKAVYDADRAAKLQFAITKLRLALAQDEPVPLSPYFAAVEKLTTDEKDTKD ALLGSIIAAVPQEALEQGVLSPAQLAARFHLLEPEIRKASLLPPNAGIAGHIGSLVFSKLLWKKEGNPTGDDVEAILARA NTALSEGRTTDAVAEVNTLKGWPKRLASDWLAEGRKRSEVEFLTDLLIEEGKLWL
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.