Protein

MIA_01716_1

Length
291 amino acids

Browser: contig02:1490795-1491727-

Protein function

EGGNOG:0PJ47AYR1)-reductase
SGD closest match:S000001386AYR1NADPH-dependent 1-acyldihydroxyacetone phosphate reductase
CGD closest match:CAL0000181438AYR1Acylglycerone-phosphate reductase

Protein alignments

%idAln lengthE-value
MCA_02394_166.667%2916.90e-147MCA_02394_1
A0A0J9XKL2_GEOCN62.963%2708.90e-120Similar to Saccharomyces cerevisiae YIL124W AYR1 NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles OS=Geotrichum candidum GN=BN980_GECA32s00219g PE=3 SV=1
UniRef50_A0A0J9XKL262.963%2701.82e-116Similar to Saccharomyces cerevisiae YIL124W AYR1 NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKL2_GEOCN
A0A1E3PM71_9ASCO48.496%2669.14e-89NAD(P)-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45982 PE=3 SV=1
A0A060T1R0_BLAAD46.520%2731.54e-83ARAD1C26708p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C26708g PE=3 SV=1
A0A1D8PJ12_CANAL44.128%2817.72e-75Acylglycerone-phosphate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AYR1 PE=4 SV=1
A0A167DT70_9ASCO45.299%2342.10e-69Acylglycerone-phosphate reductase OS=Sugiyamaella lignohabitans GN=AYR1 PE=3 SV=1
AYR1_YEAST40.909%2864.02e-68NADPH-dependent 1-acyldihydroxyacetone phosphate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AYR1 PE=1 SV=1
A0A1E4TJR7_9ASCO33.668%1992.61e-23Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30293 PE=3 SV=1
Q6CCQ8_YARLI35.714%1961.31e-22YALI0C07414p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C07414g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8491

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 291

Detailed signature matches

  1. Family IPR002347
    Short-chain dehydrogenase/reductase SDR
    1. PR00080 (SDRFAMILY)
    2. PR00081 (GDHRDH)
    3. PF00106 (adh_short)
  2. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  3. SITE IPR020904
    Short-chain dehydrogenase/reductase, conserved site
    1. PS00061 (ADH_SHORT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. SM00822 (PKS_KR)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd05374 (17beta-HSD...)

Residue annotation

  1. NADP binding site ...
  2. active site cd05374
  3. steroid binding si...

Protein sequence

>MIA_01716_1
MSKSHLSESTPSSLKTALVTGASSGIGKALARELFVKGYAVFAGARRVDEMADLADLGITTVSLDVTSKESIDKIISLIR
EQTGRLDILFNNAGTSCTFPVTDLKLEDAKSCFDVNFFGVIQVTQAAIPLLKETKGTIVQTGSVASILPFPFGSVYAASK
AALHQFSNVLRVELKPFDIRVVVLTVAAVNTSIADTRALPQDSWYYEIEEGIQSRRSMAKDNTPMEPDVFAKKIIPQVIC
ANPKRTIWGGGHAWLLWFLSLFPRFLVELIFYYKFQLAKLHSYKNQKRLTG

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.