Protein

MCA_02394_1

Length
294 amino acids

Gene name: AYR1

Description: NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

Browser: contigB:1156094-1156979+

RNA-seq: read pairs 440, FPKM 18.4, percentile rank 39.2% (100% = highest expression)

Protein function

Annotation:AYR1NADPH-dependent 1-acyldihydroxyacetone phosphate reductase
KEGG:K06123AYR1 1-acylglycerone phosphate reductase [EC:1.1.1.101]
EGGNOG:0PJ47AYR1)-reductase
SGD closest match:S000001386AYR1NADPH-dependent 1-acyldihydroxyacetone phosphate reductase
CGD closest match:CAL0000181438AYR1Acylglycerone-phosphate reductase

Protein alignments

%idAln lengthE-value
MIA_01716_168.73%2756e-144MIA_01716_1
A0A0J9XKL2_GEOCN64.23%2742e-122Similar to Saccharomyces cerevisiae YIL124W AYR1 NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles OS=Geotrichum candidum GN=BN980_GECA32s00219g PE=3 SV=1
UniRef50_A0A0J9XKL264.23%2745e-119Similar to Saccharomyces cerevisiae YIL124W AYR1 NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKL2_GEOCN
A0A060T1R0_BLAAD48.21%2801e-90ARAD1C26708p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C26708g PE=3 SV=1
A0A1E3PP22_9ASCO44.20%2762e-81NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50582 PE=3 SV=1
A0A1D8PJ12_CANAL44.88%2831e-77Acylglycerone-phosphate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AYR1 PE=4 SV=1
A0A167DT70_9ASCO48.54%2391e-74Acylglycerone-phosphate reductase OS=Sugiyamaella lignohabitans GN=AYR1 PE=3 SV=1
AYR1_YEAST41.90%2844e-71NADPH-dependent 1-acyldihydroxyacetone phosphate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AYR1 PE=1 SV=1
A0A1E4TJR7_9ASCO33.51%1852e-21Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30293 PE=3 SV=1
Q6CCQ8_YARLI33.68%1936e-20YALI0C07414p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C07414g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8976
Predicted cleavage: 52

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 294

Detailed signature matches

  1. Family IPR002347
    Short-chain dehydrogenase/reductase SDR
    1. PR00080 (SDRFAMILY)
    2. PR00081 (GDHRDH)
    3. PF00106 (adh_short)
  2. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  3. SITE IPR020904
    Short-chain dehydrogenase/reductase, conserved site
    1. PS00061 (ADH_SHORT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. TRANSMEMBRANE (Tran...)
  5. cd05374 (17beta-HSD...)

Residue annotation

  1. NADP binding site ...
  2. active site cd05374
  3. steroid binding si...

Protein sequence

>MCA_02394_1
MASSSLATSSYDSISKLKTALVTGASSGIGKGIAKELFAQGYTVFAGARRVEAMDDLASLGIHTLHLDVTDDDSVNNVIS
MIEQETGRLDLLFNNAGTSCTFPGADVTVADAKQCFDVNFFGVIRMTRAAIPLLKESKGTIVQTGSVAAILPFPFGSVYS
ASKAALHQYSNVLRIELKPFDIKVVVMCVAAVDTNIADNRPLPQSSLYSHIDDGIQARRTMAKDNNPMHPTTFAKHVVPQ
VIGSRPKRTVWSGRGAWFLWILSLMPKWVIEYIFYQKFYLAKLASFVSKRKKLQ

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.