Protein

MIA_01714_1

Length
408 amino acids

Browser: contig02:1485680-1486907-

Protein function

EGGNOG:0PIXIPGUG_03957protease
SGD closest match:S000004111YPS3Aspartic proteinase yapsin-3
CGD closest match:CAL0000189556SAP1Candidapepsin-1

Protein alignments

%idAln lengthE-value
MCA_02396_166.011%3561.48e-171MCA_02396_1
A0A161HF64_9ASCO36.712%3654.16e-74Yps1p OS=Sugiyamaella lignohabitans GN=YPS1 PE=3 SV=1
UniRef50_A0A161HF6436.712%3651.14e-70Yps1p n=3 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HF64_9ASCO
A0A060TCA1_BLAAD36.815%3831.46e-69ARAD1B22000p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22000g PE=3 SV=1
Q6C6E4_YARLI32.955%4401.15e-56YALI0E10175p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E10175g PE=3 SV=1
M1XFD0_GEOCN32.783%4242.08e-53Aspartic protease OS=Geotrichum candidum GN=YSP3 PE=3 SV=1
A0A1E3PJQ9_9ASCO32.381%4209.20e-47Acid protease OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46336 PE=3 SV=1
YPS3_YEAST31.714%3911.10e-46Aspartic proteinase yapsin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPS3 PE=1 SV=1
CARP1_CANAL35.362%3453.15e-44Candidapepsin-1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SAP1 PE=1 SV=1
A0A1E4TI13_9ASCO30.220%3642.92e-29Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_123212 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0251

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 408

Detailed signature matches

  1. Family IPR001461
    Aspartic peptidase A1 family
    1. PR00792 (PEPSIN)
  2. Domain IPR021109
    Aspartic peptidase domain
    1. G3DSA:2.40.70.10
    2. SSF50630 (Acid prot...)
  3. Domain IPR033121
    Peptidase family A1 domain
    1. PS51767 (PEPTIDASE_A1)
    2. PF00026 (Asp)
  4. Domain IPR033876
    Secreted aspartic endopeptidase
    1. cd05474 (SAP_like)
  5. SITE IPR001969
    Aspartic peptidase, active site
    1. PS00141 (ASP_PROTEASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Residue annotation

  1. inhibitor binding ...
  2. catalytic residue ...
  3. catalytic motif cd...
  4. Active site flap c...

Protein sequence

>MIA_01714_1
MKVLLFLLIIIFPLIYGAPSDSLSNSPSGVIQFETFQNFRQVDSVKELVKRSTDFHGTIDLKNYLSYYTIDFKAGTPFQN
VSTVLDTGSSDLWFYDKSSGRNTYFDSKSSSTYLYKDSTLFISYGSGPVKGDWGADVLQFGNAILNNSTIGLVTRDSLRG
APIPGILGLGRISNEATPNKYDNVPARLKNEGHIKRNSFSIYLNSLNSGVGSILFGGVDSSRYIEPLYEIPMANESHISI
ELSSVSLKLHGETQLINNTNSRAALLDTGTSFTYLPDSAFNAIVKALGATYNPFFGVYFVSNITEKTPSLSFNFSGAEIV
VPAVEYVLPVRLFTTESTPAPYILSIFRSSDIRGLTILGANFLRSSYTVFDVTGNKVALAQAKYDVSGTSVKQIISGIPG
ATSAPAIK

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004190 aspartic-type endopeptidase activity

Cellular Component

None predicted.