Protein

MCA_02396_1

Length
403 amino acids


Description: aspartic protease

Browser: contigB:1160518-1161730+

RNA-seq: read pairs 18, FPKM 0.6, percentile rank 7.2% (100% = highest expression)

Protein function

Annotation:aspartic protease
EGGNOG:0PIXIOPSBprotease
SGD closest match:S000004111YPS3Aspartic proteinase yapsin-3
CGD closest match:CAL0000196689SAP2Candidapepsin-2

Protein alignments

%idAln lengthE-value
MIA_01714_166.02%3597e-155MIA_01714_1
A0A060TCA1_BLAAD35.26%3464e-54ARAD1B22000p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22000g PE=3 SV=1
UniRef50_A0A060TCA135.26%3461e-50ARAD1B22000p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060TCA1_BLAAD
A0A161HF64_9ASCO35.63%3482e-53Yps1p OS=Sugiyamaella lignohabitans GN=YPS1 PE=3 SV=1
Q6CI40_YARLI32.52%3696e-40YALI0A02002p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A02002g PE=3 SV=1
M1XFD0_GEOCN33.33%3994e-37Aspartic protease OS=Geotrichum candidum GN=YSP3 PE=3 SV=1
CARP2_CANAL32.24%3354e-34Candidapepsin-2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SAP2 PE=1 SV=1
YPS3_YEAST30.57%3866e-34Aspartic proteinase yapsin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPS3 PE=1 SV=1
A0A1E3PQ20_9ASCO30.99%3846e-31Acid protease (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_9777 PE=3 SV=1
A0A1E4TI13_9ASCO28.78%3449e-23Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_123212 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0262

Protein family membership

Domains and repeats

1 50 100 150 200 250 300 350 403

Detailed signature matches

    1. PR00792 (PEPSIN)
    1. SSF50630 (Acid prot...)
    1. PS51767 (PEPTIDASE_A1)
    2. PF00026 (Asp)
    1. cd05474 (SAP_like)
    1. PS00141 (ASP_PROTEASE)

Residue annotation

  1. inhibitor binding ...
  2. catalytic residue ...
  3. catalytic motif cd...
  4. Active site flap c...

Protein sequence

>MCA_02396_1
MAIAKRDDTKFNGSIDVKNYLSFYTVDFHAGTPLQPVTAVLDTGSSDMWFYDKISGRRPFFDSSASSTYVKKDSSLYISY
GSGPVRGNWGTDTIRFGNVKLENTMFGLVTNDLLRGAAIPGILGLGRISNEARTEKYDNLPARLYKEGHINRMAYSVYLN
NLNSGVGNVLFGGVDSARYIEPLYEIPMANDSHLAVELTGVATRSKEGKIDFIPASSARFALLDTGTSFTYLPDAVYSQI
YRRLNATYSNEFGISFVQNITDDTPDLVFNIKGIRITVSASEYVLPVKLFTTQPTPAPYILSIFRSSDIRGMTILGANFM
RSAYTVFDITGNKVALAQARHDVYNVSSIKPIVDGIPGAISPHIYQPNYNGSRQRAVSGSGFYPFESLPRRSNILGSLQN
LLW

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004190 aspartic-type endopeptidase activity

Cellular Component

None predicted.