Protein

MIA_01681_1

Length
382 amino acids

Browser: contig02:1382137-1383286-

Protein function

EGGNOG:0PHMPGPD1Glycerol-3-phosphate dehydrogenase
SGD closest match:S000002180GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)] 1
CGD closest match:CAL0000200026GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]

Protein alignments

%idAln lengthE-value
MCA_01066_167.574%4040.0MCA_01066_1
A0A0J9X7I2_GEOCN68.717%3740.0Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Geotrichum candidum GN=BN980_GECA03s07193g PE=3 SV=1
A0A1E3PDY7_9ASCO59.341%3641.82e-160Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47988 PE=3 SV=1
A0A060SX46_BLAAD59.673%3674.86e-156Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A10560g PE=3 SV=1
GPD1_YARLI59.726%3651.91e-154Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=GPD1 PE=3 SV=1
Q59XU9_CANAL56.649%3763.75e-149Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GPD1 PE=3 SV=1
GPD1_YEAST55.676%3702.55e-148Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPD1 PE=1 SV=4
UniRef50_Q0005555.676%3706.10e-145Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 n=121 Tax=Opisthokonta TaxID=33154 RepID=GPD1_YEAST
A0A1E4TKR2_9ASCO54.301%3721.49e-137Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_85019 PE=3 SV=1
A0A167DS97_9ASCO58.462%3257.07e-128Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Sugiyamaella lignohabitans GN=GPD2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4674
Predicted cleavage: 16

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 382

Detailed signature matches

  1. Family IPR006168
    Glycerol-3-phosphate dehydrogenase, NAD-dependent
    1. PR00077 (GPDHDRGNASE)
    2. PS00957 (NAD_G3PDH)
    3. PIRSF000114 (Glycer...)
  2. Family IPR017751
    Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic
    1. TIGR03376
  3. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  4. Domain IPR011128
    Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
    1. PF01210 (NAD_Gly3P_...)
  5. Domain IPR008927
    6-phosphogluconate dehydrogenase C-terminal domain-like
    1. SSF48179 (6-phospho...)
  6. Domain IPR013328
    6-phosphogluconate dehydrogenase, domain 2
    1. G3DSA:1.10.10...
  7. Domain IPR006109
    Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal
    1. PF07479 (NAD_Gly3P_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...

Protein sequence

>MIA_01681_1
MPTFITKAASRPFRVCVVGSGNWGTTVAKIVCENTQIHSDLFEPKVNMWVHEEEIEGRKLTEIINTQHENVKYLPGIQLP
TNLQAVPSLLEAVRDSNIIVFNIPHQFLRTVCAQLKGHVHPHTRAISCLKGLDVSADKITTLPAYISQSLGIHCGALSGA
NLAPEIAQEKFSETTVAYRYPSAEEWKPADELQDVTKDDLRTLFHRPYFHVNVIDDITGVCLAGALKNVVAIAAGFVDGR
GWGENAKAAIMRRGLLEMVQFGQTFFKGGDPRTYTEESAGVADLITSCAGGRNHRVGRAYGKLTKENPDITKTLQDLERE
LLNGQSAQGILTAVEVYKFLKTQNALEQFPLMTATYRIAFEGESIDELPKILEQVEKKKYKL

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006072 glycerol-3-phosphate metabolic process
GO:0046168 glycerol-3-phosphate catabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803 protein homodimerization activity
GO:0051287 NAD binding

Cellular Component

GO:0009331 glycerol-3-phosphate dehydrogenase complex