Protein

MCA_01066_1

Length
408 amino acids

Gene name: GPD1

Description: Glycerol-3-phosphate dehydrogenase [NAD(+)]

Browser: contigA:3391863-3393090+

RNA-seq: read pairs 5819, FPKM 175.8, percentile rank 86.6% (100% = highest expression)

Protein function

Annotation:GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]
KEGG:K00006GPD1 glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]
EGGNOG:0PHMPGPD1Glycerol-3-phosphate dehydrogenase
SGD closest match:S000002180GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)] 1
CGD closest match:CAL0000200026GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]

Protein alignments

%idAln lengthE-value
MIA_01681_167.57%4040.0MIA_01681_1
A0A0J9X7I2_GEOCN64.14%3960.0Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Geotrichum candidum GN=BN980_GECA03s07193g PE=3 SV=1
A0A1E3PCF3_9ASCO55.98%3935e-156Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84571 PE=3 SV=1
A0A060SX46_BLAAD55.53%3894e-150Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A10560g PE=3 SV=1
GPD1_YARLI53.57%3929e-147Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=GPD1 PE=3 SV=1
Q59XU9_CANAL55.70%3862e-146Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GPD1 PE=3 SV=1
UniRef50_G8C24254.27%3987e-143Glycerol-3-phosphate dehydrogenase [NAD(+)] n=13 Tax=Fungi TaxID=4751 RepID=G8C242_TETPH
GPD1_YEAST52.88%3992e-142Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPD1 PE=1 SV=4
A0A1E4TKR2_9ASCO52.91%3953e-135Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_85019 PE=3 SV=1
A0A167DS97_9ASCO54.44%3495e-123Glycerol-3-phosphate dehydrogenase [NAD(+)] OS=Sugiyamaella lignohabitans GN=GPD2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7594
Predicted cleavage: 16

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 408

Detailed signature matches

  1. Family IPR006168
    Glycerol-3-phosphate dehydrogenase, NAD-dependent
    1. PR00077 (GPDHDRGNASE)
    2. PS00957 (NAD_G3PDH)
    3. PIRSF000114 (Glycer...)
  2. Family IPR017751
    Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic
    1. TIGR03376
  3. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  4. Domain IPR011128
    Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
    1. PF01210 (NAD_Gly3P_...)
  5. Domain IPR008927
    6-phosphogluconate dehydrogenase C-terminal domain-like
    1. SSF48179 (6-phospho...)
  6. Domain IPR013328
    6-phosphogluconate dehydrogenase, domain 2
    1. G3DSA:1.10.10...
  7. Domain IPR006109
    Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal
    1. PF07479 (NAD_Gly3P_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MCA_01066_1
MTSFVTRASVRPFRICVIGSGNWGTTVAKIVSENTVQYPHLFDSRVTMWVHEELINGRPLTEIINTKHENVKYLPDIKLP
TNLVAVPNIVDAIRGVNLIIFNVPHQFLVPICKQLKGYIHPHTRAISCLKGINVSEKGCMTLPDYIEKTLGIHCGALSGA
NLASEIAQGKFSETTVAYRHPQEGSPFKFDKTTIESLSPEQQEELKDLSVEELEKYDLNKDDLYKLFHKPYFHVNVIEDV
TGISLAGALKNVVAIAAGFVDGKGWGENAKAAIMRRGLLEMVRFGQTFFSDSDPRTYTEESAGVADLITSCAGGRNHRVG
KEYGRLSNGPGPYKSLQELEKELLNGQSAQGILTALEVYKFLEARDALKDFPLMAYTYQIAFEGKDINDLPGILEEVEKH
HYEDSPKL

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006072 glycerol-3-phosphate metabolic process
GO:0046168 glycerol-3-phosphate catabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803 protein homodimerization activity
GO:0051287 NAD binding

Cellular Component

GO:0009331 glycerol-3-phosphate dehydrogenase complex