Protein

MIA_01662_1

Length
329 amino acids

Browser: contig02:1333474-1334464-

Protein function

EGGNOG:0PKTCTSC13steroid alpha reductase family protein
SGD closest match:S000002173TSC13Very-long-chain enoyl-CoA reductase
CGD closest match:CAL0000194246orf19.3293Trans-2-enoyl-CoA reductase (NADPH)

Protein alignments

%idAln lengthE-value
MCA_04458_174.242%3300.0MCA_04458_1
A0A1E3PMG6_9ASCO58.075%3223.93e-132Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46039 PE=4 SV=1
A0A167DYD4_9ASCO55.891%3316.80e-128Trans-2-enoyl-CoA reductase (NADPH) TSC13 OS=Sugiyamaella lignohabitans GN=TSC13 PE=4 SV=1
UniRef50_A0A167DYD455.891%3311.87e-124Trans-2-enoyl-CoA reductase (NADPH) TSC13 n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167DYD4_9ASCO
A0A060TGG3_BLAAD56.535%3292.30e-127ARAD1D30294p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30294g PE=4 SV=1
Q6CHU1_YARLI49.226%3236.11e-114YALI0A04983p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A04983g PE=4 SV=1
A0A1D8PCD8_CANAL48.640%3313.47e-101Trans-2-enoyl-CoA reductase (NADPH) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3293 PE=4 SV=1
A0A1E4TG87_9ASCO47.077%3255.37e-100Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148049 PE=4 SV=1
TECR_YEAST33.544%3163.80e-38Very-long-chain enoyl-CoA reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSC13 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0607

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 329

Detailed signature matches

  1. Domain IPR001104
    3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
    1. PS50244 (S5A_REDUCTASE)
    2. PF02544 (Steroid_dh)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_01662_1
MSEIAIKPKRGKISNCPTAFTGPLTEPVQAVVKSISDKTGLSIHRIRLTIPTAADDKPQEPNQKKRDTVLDPALPLSTYF
SASSSSPTIYVKDLGPQIQWRTVFFIEYFGPLLIHPIFYFGQKAIYGSTFEHSRVQQFAFIFTMLHFIKREFETAFVHHF
SLDTMPVFNVFKNSSHYWFLSGINLAYFIYAPDSYSAPEKSIISRFLFGRNIVPLGATALYVLSALWLFAELSNGWTHLI
LSSLRSDGSKTRKIPYGYGFNLVSVPNYFFESLGWFALLLITQNWTSLLFFAVSTTQMWFWGVKKHRRYRKEFGDKYPKN
RKIYVPFVI

GO term prediction

Biological Process

GO:0006629 lipid metabolic process

Molecular Function

GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors

Cellular Component

GO:0005737 cytoplasm
GO:0016021 integral component of membrane