Protein

MCA_04458_1

Length
326 amino acids

Gene name: TSC13

Description: Very-long-chain enoyl-CoA reductase

Browser: contigC:3105578-3106559+

RNA-seq: read pairs 5441, FPKM 205.6, percentile rank 88.4% (100% = highest expression)

Protein function

Annotation:TSC13Very-long-chain enoyl-CoA reductase
KEGG:K10258TER very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
EGGNOG:0PKTCTSC13steroid alpha reductase family protein
SGD closest match:S000002173TSC13Very-long-chain enoyl-CoA reductase
CGD closest match:CAL0000194246orf19.3293Trans-2-enoyl-CoA reductase (NADPH)

Protein alignments

%idAln lengthE-value
MIA_01662_174.24%3302e-180MIA_01662_1
A0A1E3PMG6_9ASCO59.09%3304e-138Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46039 PE=4 SV=1
A0A167DYD4_9ASCO57.45%3291e-133Trans-2-enoyl-CoA reductase (NADPH) TSC13 OS=Sugiyamaella lignohabitans GN=TSC13 PE=4 SV=1
UniRef50_A0A167DYD457.45%3293e-130Trans-2-enoyl-CoA reductase (NADPH) TSC13 n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167DYD4_9ASCO
A0A060TGG3_BLAAD54.43%3273e-123ARAD1D30294p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30294g PE=4 SV=1
Q6CHU1_YARLI48.33%3293e-114YALI0A04983p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A04983g PE=4 SV=1
A0A1E4TG87_9ASCO48.46%3241e-103Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148049 PE=4 SV=1
A0A1D8PCD8_CANAL48.48%3283e-101Trans-2-enoyl-CoA reductase (NADPH) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3293 PE=4 SV=1
TECR_YEAST34.26%3242e-45Very-long-chain enoyl-CoA reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSC13 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1308

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 326

Detailed signature matches

  1. Domain IPR001104
    3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
    1. PS50244 (S5A_REDUCTASE)
    2. PF02544 (Steroid_dh)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_04458_1
MVAIDIKPKRGKISKLPTSLDLAPTDKVQDITSAVAKATGLSIHRIRLTIPNTDDKPDDSTKRKKRDIVLESDSPISSFL
NQSTTVYVKDLGPQIGWRTVFFIEYFGPLFIHPIFYFLQQPIYGKTFDHSRVQQLAFILTMLHFLKREFETAYVHHFSLA
TMPLFNVFKNSSHYWFLSGINLAYFIYAPDSYAAEDKSIVSRVLFGRNLVPLNATQLWILTGIWLFAELSNGYTHLILSS
LRADGSKARKIPYGYGFNLVSVPNYFFESLGWFAVLLITQNWSSLLFFTVSTAQMWVWGVKKHRRYIKEFGDKYPKNRKI
YIPFIL

GO term prediction

Biological Process

GO:0006629 lipid metabolic process

Molecular Function

GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors

Cellular Component

GO:0005737 cytoplasm
GO:0016021 integral component of membrane