Protein
MIA_01612_1
Length
436 amino acids
Browser: contig02:1197665-1198976+
Protein function
| EGGNOG: | 0PIFK | transporter | |
|---|---|---|---|
| SGD closest match: | S000002286 | VCX1 | Vacuolar calcium ion transporter |
| CGD closest match: | CAL0000184577 | VCX1 | Vcx1p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_02404_1 | 74.19% | 434 | 0.0 | MCA_02404_1 |
| A0A0J9X8Q6_GEOCN | 69.57% | 391 | 3e-170 | Similar to Saccharomyces cerevisiae YDL128W VCX1 Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity OS=Geotrichum candidum GN=BN980_GECA06s00263g PE=3 SV=1 |
| A0A167DAV8_9ASCO | 63.25% | 400 | 5e-159 | Vcx1p OS=Sugiyamaella lignohabitans GN=VCX1 PE=3 SV=1 |
| Q6CF88_YARLI | 62.34% | 401 | 3e-158 | YALI0B09273p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B09273g PE=3 SV=2 |
| A0A060T6V6_BLAAD | 61.36% | 396 | 1e-145 | ARAD1B22440p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22440g PE=3 SV=1 |
| A0A1E3PED4_9ASCO | 61.96% | 397 | 6e-144 | Calcium/proton exchanger OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84343 PE=3 SV=1 |
| Q59QB4_CANAL | 62.11% | 388 | 7e-141 | Vcx1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VCX1 PE=3 SV=1 |
| UniRef50_A0A0E9NMD8 | 57.54% | 398 | 6e-127 | Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) n=1 Tax=Saitoella complicata NRRL Y-17804 TaxID=698492 RepID=A0A0E9NMD8_9ASCO |
| VCX1_YEAST | 52.28% | 417 | 9e-119 | Vacuolar calcium ion transporter OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VCX1 PE=1 SV=1 |
| A0A1E4TBM6_9ASCO | 54.48% | 391 | 9e-117 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_134275 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2178
Protein family membership
- Calcium/proton exchanger (IPR004713)
- Calcium/proton exchanger CAX (IPR004798)
Domains and repeats
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Domain
1
50
100
150
200
250
300
350
400
436
Detailed signature matches
-
-
PF01699 (Na_Ca_ex)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
Protein sequence
>MIA_01612_1 MNSTRRSSAASSNFGDDRDTSFLMKRFQAFKASRPTWTRLNSRPWVHKINNIFTSSYVNVLLIFVPLGILAYQLGWGAKA IFLLNFLAIIPLAALMGYATEEISSHVGETVGGLLNATFGNAVELIVAIVALARGEIRIVQTSMLGSILSNTLLVLGCSF IAGGYNRIQQTFNATVAQTMSSLMALAVTSLLIPAAFNSSFPHPSEPGQNTNQAVLNVSHGTAIILLVIYIFYLVFQLKT HAAYFEGMSEEGDIESAPQAISNGNETTPLLAGGSDVEDEQESTLSTWEALGLLGLITIVVSYCADYLVDSIDEIVTETG ISKTFIGVVLIPIVGNAAEHVTAIVVATKDKMDLAVGVAIGSSMQIALFLTPFCVIVGWIINQPMSLLFTTFETCVLFVS VLMLNYIVQDGESNWLEGAMLFGTYMVIAIAFWNYP
GO term prediction
Biological Process
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0055085 transmembrane transport
Molecular Function
GO:0008324 cation transmembrane transporter activity
GO:0015369 calcium:proton antiporter activity
Cellular Component
GO:0016021 integral component of membrane